Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Most Americans rate medical research as a high national priority

...and strongly support greater public and private funding, according to an article in the Journal of the American Medical Association (JAMA), a theme issue on medical research.

26 Sep 2005

Adult human neural stem cells used to successfully regenerate spinal cord tissue

Researchers at the UC Irvine Reeve-Irvine Research Center have used adult human neural stem cells to successfully regenerate damaged spinal cord tissue and improve mobility in mice.

26 Sep 2005

Study reveals critical molecular events in the origin of fat cells

A new study reveals critical molecular events in the origin of fat cells. The findings are central to understanding chronic diseases, such as obesity and diabetes, as fat cells produce hormones critical for metabolic control, the researchers said.

21 Sep 2005

Drug AMD-3100 may help cancer patients who need stem cell transplants

A new drug may help cancer patients mobilize the cells necessary to restore their blood-forming system after high-dose chemotherapy, according to results from a clinical trial at the Kimmel Cancer Center at Thomas Jefferson University Hospital in Philadelphia and at other centers across the nation.

19 Sep 2005

Workshop - stem cells in reproduction and in the brain

"Once we have found the factors by which body cells can be re-programmed into stem cells, then therapeutic cloning might become superfluous," said Hans R. Scholer, director of the Max Planck Institute for Molecular Biomedicine in Munster, Germany, at an international scientific symposium on stem cell research in Kobe, Japan.

10 Sep 2005

Sugar-coated markers of brain cell development may help success of stem cell transplants

Four sugar-coated faces made by stem cells as they differentiate into brain cells during development have been identified by scientists.

10 Sep 2005

Key to stem cell transplant success is tricking immune system

Tricking the body's immune system into ignoring stem cells will be the key to successful stem cell transplants, according to Professor Maggie Dallman, Imperial College London, speaking this week at the BA Festival of Science.

10 Sep 2005

Human embryonic stem cell lines accumulate changes in their genetic material over time

The findings do not limit the utility of the cells for some types of research or for some future clinical applications, the researchers say, but draw attention to the need to closely monitor stem cell lines for genetic changes and to study how these alterations affect the cells' behavior.

6 Sep 2005

Human tissue grown from stem cells, available for transplant in the next four years

A team of researchers from the University of Liverpool in the UK have embarked on an ambitious project which could see human tissue grown from stem cells, available for transplant in the next four years.

5 Sep 2005

Human embryonic stem cell lines accumulate changes in their genetic material over time

5 Sep 2005

UK fertility specialist and broadcaster says embryonic stem cell research promises are hyped up

According to a well known fertility specialist and broadcaster in the UK, the promise of embryonic stem cell research has been oversold by scientists.

5 Sep 2005

New key evidence supports claims that some types of cancer originate with defects in stem cells

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Institute of Biomedical Research of the Parc Científic de Barcelona (IRB-PCB) have now added key evidence to claims that some types of cancer originate with defects in stem cells.

4 Sep 2005

Release of the neurotransmitter GABA halts stem cell production in the brain

Release of the neurotransmitter GABA by adult neuronal precursor cells that develop into neurons limits stem cell proliferation, according to a study at Yale School of Medicine in the September issue of Nature Neuroscience.

1 Sep 2005

Rev/Dex combo looks like a breakthrough treatment for multiple myeloma

Mayo Clinic Cancer Center investigators report that combination therapy with lenalidomide (Revlimid) and dexamethasone (combination is called Rev/Dex) looks like a breakthrough treatment for multiple myeloma. Results of a Phase II clinical trial were published online Aug. 23 in Blood.

1 Sep 2005

First human trials start in Canada for muscle-derived stem cells as a treatment for urinary incontinence

Human muscle-derived cells, pluripotent stem cells found in muscle, have been used to cure stress urinary incontinence in animal models, a finding which signals that these cells are prime candidates to treat the condition in adults.

31 Aug 2005

Anti-cancer antibodies produced in chickens

A team of researchers have produced the first fully functional, human sequence monoclonal antibodies (mAbs) in chickens.

29 Aug 2005

High-dose anticancer chemotherapy and total body irradiation during childhood can damage developing teeth

Research published by the University of Helsinki, Finland, indicates that cytostatic and radiation therapies administered before stem cell transplantation often damage children's permanent teeth.

29 Aug 2005

Making human lungs in the lab a future possibility

Scientists in the UK say they have made a significant step towards making human lungs for transplantation.

25 Aug 2005

Stem cells with heart bypass surgery trial to begin

The University of Pittsburgh Medical Center (UPMC) has been granted approval by the U.S. Food and Drug Administration (FDA) to conduct a clinical trial to determine the safety and feasibility of injecting a patient's own bone marrow-derived stem cells directly into the heart during conventional heart bypass surgery.

25 Aug 2005

Scientists convert human embryonic stem cells into lung cells

According to research to be published in the journal Tissue Engineering, the team from Imperial College London, took human embryonic stem cells and 'directed' them to convert into the type of cells needed for gas exchange in the lung, known as mature small airway epithelium.

24 Aug 2005

Stem Cells News and Research

Further Reading

Most Americans rate medical research as a high national priority

Adult human neural stem cells used to successfully regenerate spinal cord tissue

Study reveals critical molecular events in the origin of fat cells

Drug AMD-3100 may help cancer patients who need stem cell transplants

Workshop - stem cells in reproduction and in the brain

Sugar-coated markers of brain cell development may help success of stem cell transplants

Key to stem cell transplant success is tricking immune system

Human embryonic stem cell lines accumulate changes in their genetic material over time

Human tissue grown from stem cells, available for transplant in the next four years

Human embryonic stem cell lines accumulate changes in their genetic material over time

UK fertility specialist and broadcaster says embryonic stem cell research promises are hyped up

New key evidence supports claims that some types of cancer originate with defects in stem cells

Release of the neurotransmitter GABA halts stem cell production in the brain

Rev/Dex combo looks like a breakthrough treatment for multiple myeloma

First human trials start in Canada for muscle-derived stem cells as a treatment for urinary incontinence

Anti-cancer antibodies produced in chickens

High-dose anticancer chemotherapy and total body irradiation during childhood can damage developing teeth

Making human lungs in the lab a future possibility

Stem cells with heart bypass surgery trial to begin

Scientists convert human embryonic stem cells into lung cells

Stem Cells eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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