Structural Biology News and Research

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Platforms for NMR software for spectrometer control and data analysis announced by Bruker

New Magnetic Resonance Technologies and Applications Open New Frontiers for Biological, Chemical and Materials Research and Routine Analysis in Pharmaceutical and Chemical Industries.

28 Mar 2017

Researchers unravel how drug interacts with ribosome to halt protein production

The discovery of a chemical compound that halts the production of a small set of proteins while leaving general protein production untouched suggests a new drug search strategy: Find compounds that target undesired proteins before they are even made.

23 Mar 2017

High-resolution images of protein complex performing first step in genome-replication dance captured

It's a good thing we don't have to think about putting all the necessary pieces in place when one of our trillions of cells needs to duplicate its DNA and then divide to produce identical daughter cells.

17 Mar 2017

Scientists identify new toxic pathway for protein aggregates in ALS and FTLD

Led by professor Ludo Van Den Bosch, scientists from Belgium, the UK and the US have identified new processes that form protein "clumps" that are characteristic of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD).

17 Mar 2017

Investigational RSV vaccine protects cattle from respiratory diseases

A novel vaccine developed by scientists at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, protected cattle from respiratory syncytial virus (RSV) infection, according to research published online in npj Vaccines on March 8.

10 Mar 2017

Hypoxia in primary tumors influences dormant DTCs that evade cancer therapy, study shows

In a first of its kind study, Mount Sinai researchers have discovered the conditions by which specific signals in primary tumors of head and neck and breast cancers, pre-program cancer cells to become dormant and evade chemotherapy after spreading.

28 Jan 2017

Scientists reveal chemical process behind anti-cancer properties of spicy pepper plant

UT Southwestern Medical Center scientists have uncovered the chemical process behind anti-cancer properties of a spicy Indian pepper plant called the long pepper, whose suspected medicinal properties date back thousands of years.

4 Jan 2017

Massive sequencing and coevolution unveils secrets of human protein interactions

Cells operate like an incredibly well-synchronized orchestra of molecular interactions among proteins. Understanding this molecular network is essential not only to understand how an organism works but also to determine the molecular mechanisms responsible for a multitude of diseases.

30 Dec 2016

TSRI scientists shed light on how antiviral drug stops influenza infections

A new study led by scientists at The Scripps Research Institute (TSRI) is the first to show exactly how the drug Arbidol stops influenza infections. The research reveals that Arbidol stops the virus from entering host cells by binding within a recessed pocket on the virus.

22 Dec 2016

Mount Sinai researchers laying groundwork to find effective treatment for Zika virus

Researchers at the Icahn School of Medicine at Mount Sinai are working on the basic science that lays the groundwork to finding a way to treat and prevent the Zika virus, a global health risk.

22 Dec 2016

Scientists detail structure of molecule implicated in Alzheimer's disease

Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer's disease.

21 Dec 2016

UT Southwestern researchers develop new imaging method to see proteins in action

UT Southwestern Medical Center researchers developed a new imaging technique that makes X-ray images of proteins as they move in response to electric field pulses.

16 Dec 2016

Scientists develop easy-to-use software tool to detect important genetic mutations

Scientists have developed an easy-to-use software tool that can detect important genetic mutations that previously needed to be identified by a separate test.

29 Nov 2016

Elucidating IDP behaviour on crowded membranes

IDPs are proteins that contain stretches of amino-acid sequence that are flexible and do not comprise stable structure in isolation. This is in contrast with a more traditional view of proteins as largely occupying a stable native structure that correlates with functions such as enzyme activity or binding.

10 Nov 2016

Scientists unravel viral molecular strategies to counter mammalian immune system

As mammals evolve, so do mammalian viruses. In doing so, they develop creative and effective ways to counter and evade the antiviral responses of their mammal hosts' immune systems.

7 Nov 2016

TSRI scientists discover reason for lack of successful HCV vaccine design

Researchers have been trying for decades to develop a vaccine against the globally endemic hepatitis C virus (HCV). Now scientists at The Scripps Research Institute have discovered one reason why success has so far been elusive.

24 Oct 2016

Researchers discover how toxic proteins linked to neurological diseases impair membrane-less organelles

Researchers at St. Jude Children's Research Hospital have discovered the way toxic proteins linked to the most common forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) incapacitate membrane-less organelles inside cells.

21 Oct 2016

UCLA scientists take promising step towards killing mosquitoes that carry Zika virus and dengue fever

Five UCLA researchers were part of an international team that has used X-rays to reveal the structure of a molecule that is toxic to disease-carrying mosquitoes.

18 Oct 2016

Diamond publishes milestone paper that reveals discovery of genetic triggers behind birth defects

Researchers at the UK's national synchrotron facility, Diamond Light Source, have just published the 5000th scientific paper using data from the facility. This milestone marks a significant step for the synchrotron that is used by over 8,000 scientists each year.

7 Oct 2016

Research uncovers new clues to combat dengue and Zika virus

Structural biology research conducted at the U.S. Department of Energy's SLAC National Accelerator Laboratory has uncovered how small insecticidal protein crystals that are naturally produced by bacteria might be tailored to combat dengue fever and the Zika virus.

28 Sep 2016