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Review: Biomimetic strategies for bone healing need to emulate natural regenerative mechanisms

The range of biomimetic approaches to promote bone growth that are at the core of current bone healing therapies need to more closely emulate natural regenerative mechanisms.

15 Feb 2017

Scientists develop safe, effective vaccine for chikungunya fever from insect-specific virus

Researchers from The University of Texas Medical Branch at Galveston have developed the first vaccine for chikungunya fever made from an insect-specific virus that doesn't have any effect on people, making the vaccine safe and effective.

20 Dec 2016

UC Riverside scientists identify mechanism that creates immunity to influenza A virus

A team of researchers, co-led by a University of California, Riverside professor, has found a long-sought-after mechanism in human cells that creates immunity to influenza A virus, which causes annual seasonal epidemics and occasional pandemics.

5 Dec 2016

Neurons appear to retain partial communication despite serious structural aberrations, study finds

Neuroscientists have long known that brain cells communicate with each other through the release of tiny bubbles packed with neurotransmitters—a fleet of vessels docked along neuronal ends ready to launch when a trigger arrives.

24 Nov 2016

Rearrangement of collagen linked to poor outcomes in pancreatic cancer patients

A study in the current journal Oncotarget provides the first evidence linking a disturbance of the most common protein in the body with a poor outcome in pancreatic cancer.

21 Oct 2016

Novel method can quantify progression of NAFLD to more advanced fibrosis and cirrhosis

Combining multiple non-invasive measures, researchers at University of California San Diego School of Medicine describe a novel method to quantify the progression of nonalcoholic fatty liver disease (NAFLD) to its more dangerous and deadly states — advanced fibrosis and cirrhosis.

12 Oct 2016

NIH funds collaborative project to develop better vaccine adjuvants for many diseases

Dr. Qizhi Cathy Yao, professor of surgery, molecular virology and microbiology, and pathology & immunology at Baylor College of Medicine, has been awarded a National Institutes of Health grant to fund a collaborative project with Molecular Express, Inc.

12 Aug 2016

Penn researchers develop plant-based oral vaccine booster

Jonas Salk created a vaccine against polio that has been used since 1955; Albert Sabin created another version that has been on the market since 1961. Together, these two vaccines have nearly eliminated polio from the face of the earth.

20 Jul 2016

Scientists discover X-chromosome-inherited type of osteogenesis imperfecta

Researchers from the University of Zurich and University Children's Hospital Zurich have discovered the first X-chromosome-inherited type of the congenital disease osteogenesis imperfecta, also known as brittle-bone disease.

6 Jul 2016

Lack of Alix protein leads to occurrence of hydrocephalus in the brain

A team led by researchers at St. Jude Children's Research Hospital report that mice lacking the protein Alix develop hydrocephalus or "water on the brain." Alix ensures that epithelial cells of the choroid plexus are oriented correctly with respect to one another to prevent compromise of the epithelial barrier.

23 Jun 2016

Blend of pulverized natural bone and man-made plastic can create 3D printed replacement bones

To make a good framework for filling in missing bone, mix at least 30 percent pulverized natural bone with some special man-made plastic and create the needed shape with a 3-D printer. That's the recipe for success reported by researchers at The Johns Hopkins University in a paper published April 18 online in ACS Biomaterials Science & Engineering.

5 May 2016

Healthy cells actively collaborate with tumours to promote growth of new blood vessels

Healthy cells actively collaborate with tumours by creating a mesh of collagen that encourages cancer cells to build new blood vessels, a new study shows.

4 Mar 2016

SBP researchers identify molecular switch that controls genes needed to repair skeletal muscle

Researchers at Sanford Burnham Prebys Medical Research Institute (SBP) have conclusively identified the protein complex that controls the genes needed to repair skeletal muscle.

11 Feb 2016

Dynamic light scattering technique may help detect people at risk of cataracts and presbyopia

As we age, proteins in the lenses of our eyes start misbehaving: They unfold and congregate in clusters that block, scatter and distort light as it passes through the lens. A cloudy area, or cataract, forms. In a new study, scientists found that throughout our lifetime, levels of a key protein decline, and may be an early warning sign of a developing cataract.

23 Dec 2015

Duchenne muscular dystrophy could directly affect muscle stem cells

A new study from The Ottawa Hospital and the University of Ottawa is poised to completely change our understanding of Duchenne muscular dystrophy and pave the way for far more effective treatments.

18 Nov 2015

CK5 protein marks ovarian cancer likely to be resistant to cisplatin

A University of Colorado Cancer Center study recently published in the International Journal of Gynecological Cancer shows that protein cytokeratin 5 (CK5), known to be a marker of poor prognosis in breast cancer, also marks ovarian cancers likely to be resistant to the common chemotherapy cisplatin.

5 Nov 2015

Researchers discover two new structures in cornea of human eye

"It's not everyday that one newly discovers parts of the human body," says Roy S. Chuck, MD, PhD, Chairman Department of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine.

31 Oct 2015

UTMB scientists work with InBios International to develop novel diagnostic test for chikungunya

A novel and affordable diagnostic test for chikungunya will soon be available thanks to the work of researchers at the University of Texas Medical Branch at Galveston in partnership with a commercial lab.

30 Oct 2015

Novogen’s chemotherapy drug Anisina proves as effective anti-cancer agent in animals

US-Australian drug discovery company, Novogen Limited announced today that its candidate cytotoxic chemotherapy drug, Anisina, has proved an effective anti-cancer agent in animals, the result of which it now has been fast-tracked by the Company to come into the clinic.

24 Jun 2015

LMU cardiologists study new approach to inhibit atherosclerotic plaque-induced platelet activation

Blood clots often form when lipid-rich plaques on the inner surface of arteries rupture and platelets aggregate at the site of injury. Cardiologists from Ludwig-Maximilians-Universitaet in Munich have now compared the effects of two new platelet aggregation inhibitors.

4 Jun 2015