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Study finds SARS-CoV-2 E protein antagonizes BET protein-mediated antiviral responses during infection

Researchers assessed the impact of SARS-CoV-2 envelope protein on the bromodomain and extraterminal domain (BET) proteins.

29 Jun 2022

The risk of SARS-CoV-2 infection and disease severity in a cohort of severe asthmatics treated with biologics

Researchers assessed the risk of SARS-CoV-2 infection in asthma patients taking biologics.

29 Jun 2022

Complex molecular dance could inform the development of future treatments for fragile X syndrome

Like many neurological diseases, there's a lot we don't understand about fragile X syndrome. But, after studying the disorder for several years, Lynne Maquat's lab knew two important things: the enzyme AKT, which plays a key role in cell growth and survival, and the quality control pathway known as NMD (nonsense-mediated mRNA decay), are both in overdrive in fragile X.

29 Jun 2022

How has COVID-19 affected the mental health of prison staff in England?

In a recent study posted to the medRxiv* preprint server, researchers at the University of Southampton, University of Manchester, and the UK Health Security Agency analyzed the impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic on the mental well-being of prison staff in England.

29 Jun 2022

Neural effects of COVID-19 on depressive symptoms

A new study identifies brain abnormalities in patients who recovered from COVID-19.

28 Jun 2022

Study explores antibody responses following three COVID vaccine doses in kidney transplant recipients

In a recent study posted to the medRxiv* pre-print server, Canadian researchers evaluated antibody responses in kidney transplant recipients (KTRs) before and one and three months after receiving the third dose of a messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine.

28 Jun 2022

Study compares protection induced by Delta breakthrough infections vs. COVID boosters against Omicron

Researchers compare the neutralizing ability of antibodies induced by Delta breakthrough infections and a third COVID-19 vaccine against Omicron.

28 Jun 2022

BNT162b2 COVID vaccine stimulates significant antibody response in lung cancer patients

In a recent article posted to the medRxiv* preprint server, scientists from Japan assessed the safety and immunogenicity of coronavirus disease 2019 (COVID-19) BNT162b2 vaccine among lung cancer patients under treatment.

28 Jun 2022

Acute COVID-19 and vaccination induce cross-reactive antibody responses in breast milk

IgA and IgG in human breast milk and blood were assessed for their activity against SARS-CoV-2 and SARS-CoV-1, as well as four other prevalent HCoVs.

28 Jun 2022

Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States described a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal antibody (mAb) SP1-77 that broadly neutralized its multiple variants of concern (VOCs).

28 Jun 2022

Duke researchers identify role for key gene in developmental disability syndrome

A single gene that was previously found to be the driving force in a rare syndrome linked to epilepsy, autism and developmental disability has been identified as a linchpin in the formation of healthy neurons.

28 Jun 2022

Study identifies a new mechanism that explains how immune cells learn to discern friend from foe

The human immune system is a nearly perfect defense mechanism. It protects the body from disease-causing bacteria, viruses, and other pathogens. It detects nascent tumors and eradicates them. It cleans up cellular debris at the site of injury or infection.

28 Jun 2022

Study identifies critical genes and biological pathways related to COVID-19 myocarditis

Scientists from China have recently deciphered the genetic network and biological mechanisms associated with COVID-19 myocarditis using bioinformatic methods.

28 Jun 2022

Antiretroviral drug used to treat HIV ameliorates cognitive deficits in mouse model of Down syndrome

Lamivudine, a commonly-used antiretroviral drug for treating HIV, improves cognition in a mouse model of Down syndrome, according to the findings of a joint new study by researchers at the Centre for Genomic Regulation (CRG) and the IrsiCaixa AIDS Research Institute, a center jointly promoted by the "la Caixa" Foundation and the Department of Health of the Generalitat de Catalunya.

28 Jun 2022

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

Researchers performed genomic comparisons between alphacoronaviruses (αCoVs) and betacoronaviruses (βCoVs) originating from South Korean Bats.

28 Jun 2022

Evolution of SARS-CoV-2 genomes based on continuing positive selection

Researchers hypothesized that ongoing positive selection strongly influences SARS-CoV-2 genomes, which plays an important role in shaping the dynamics of the COVID-19 pandemic.

28 Jun 2022

Effectiveness of monoclonal antibodies and directly acting antivirals against SARS-CoV-2 Omicron BA.1 and BA.2 sublineages

Researchers assessed the in vivo effectiveness of monoclonal antibodies and directly acting antiviral agents against the SARS-CoV-2 Omicron BA.1 and BA.2 sublineages.

28 Jun 2022

The potential of DNA-based SARS-CoV-2 vaccine candidates

Researchers evaluated the immunogenicity of DNA-based candidate vaccines against SARS-CoV-2 in mice.

28 Jun 2022

A data commons to accelerate research in COVID and long-COVID

In a recent study posted to the medRxiv* pre-print server, researchers in the United States developed a pandemic response commons (PRC) called the Chicagoland coronavirus disease 2019 (COVID-19) commons (CCC). The CCC served Chicago, the state of Illinois, and surrounding regions in the United States (US).

28 Jun 2022

Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

A recent study by scientists at Celentyx Ltd, the University of Birmingham, and the University of Warwick and posted to the bioRxiv* preprint server illustrated a cell-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein attachment assay.

28 Jun 2022

Syndrome News and Research

Study finds SARS-CoV-2 E protein antagonizes BET protein-mediated antiviral responses during infection

The risk of SARS-CoV-2 infection and disease severity in a cohort of severe asthmatics treated with biologics

Complex molecular dance could inform the development of future treatments for fragile X syndrome

How has COVID-19 affected the mental health of prison staff in England?

Neural effects of COVID-19 on depressive symptoms

Study explores antibody responses following three COVID vaccine doses in kidney transplant recipients

Study compares protection induced by Delta breakthrough infections vs. COVID boosters against Omicron

BNT162b2 COVID vaccine stimulates significant antibody response in lung cancer patients

Acute COVID-19 and vaccination induce cross-reactive antibody responses in breast milk

Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

Duke researchers identify role for key gene in developmental disability syndrome

Study identifies a new mechanism that explains how immune cells learn to discern friend from foe

Study identifies critical genes and biological pathways related to COVID-19 myocarditis

Antiretroviral drug used to treat HIV ameliorates cognitive deficits in mouse model of Down syndrome

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

Evolution of SARS-CoV-2 genomes based on continuing positive selection

Effectiveness of monoclonal antibodies and directly acting antivirals against SARS-CoV-2 Omicron BA.1 and BA.2 sublineages

The potential of DNA-based SARS-CoV-2 vaccine candidates

A data commons to accelerate research in COVID and long-COVID

Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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