Syndrome News and Research

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Decoding long COVID, pathophysiology, epidemiology, diagnosis, and management

Comprehensive review unravels the complexities of long COVID, spanning pathophysiology to management strategies, and underscores the need for targeted therapies and early diagnosis.

5 Nov 2023

High-impact clinical trial results to be presented at ASN Kidney Week 2023

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented in-person at ASN Kidney Week 2023 November 1–November 5.

3 Nov 2023

States reconsider religious exemptions for vaccinations in child care

More than half the children who attend Munchkin Land Daycare near Billings, Montana, have special needs or compromised immune systems.

3 Nov 2023

Gene discovery sheds light on ovary development

Researchers at the Francis Crick Institute and the Université Cote d'Azur, together with other labs in France and Switzerland, have identified a gene which is an early determining factor of ovary development in mice.

2 Nov 2023

Citrus compounds show zesty promise in type 2 diabetes management

Citrus compounds show promise in type 2 diabetes management, reducing blood glucose and mitigating metabolic complications without a clear threshold in humans for bioflavonoid efficacy.

2 Nov 2023

New "Core Outcome Measure Set" developed to assess the severity and impact of Long COVID

Researchers have reached an agreement on how best to measure the severity and impact of Long COVID by identifying a "Core Outcome Measure Set" (COMS).

2 Nov 2023

Scientists determine structure of key protein in neuronal communication

Neurons talk to each other using chemical signals called neurotransmitters. Scientists at St. Jude Children's Research Hospital have drawn on structural biology expertise to determine structures of vesicular monoamine transporter 2 (VMAT2), a key component of neuronal communication.

2 Nov 2023

UH researcher awarded $1.2 million grant to unravel mystery of Z-RNA

University of Houston Assistant Professor of Biology and Biochemistry Quentin Vicens has been awarded a $1.2 million grant from the National Institute of General Medical Sciences to unravel the mystery of Z-RNA – an enigmatic RNA structure within our cells that plays a critical role in immune response.

2 Nov 2023

Biomarker discovery boosts long-COVID prediction accuracy to 78.5%

Researchers identify four critical biomarkers associated with long-COVID, offering a 78.5% accuracy in predicting the condition. This discovery paves the way for diagnostic tests and offers insights into the mechanisms of persistent post-COVID symptoms.

1 Nov 2023

Masking up matters: High-quality studies confirm face masks significantly curb COVID-19 spread

This 'Special Communication' article in JAMA Network Open compiles high-quality studies to underline the effectiveness of face masks in curbing community-level transmission of SARS-CoV-2. The article emphasizes that surgical masks are more effective than cloth masks, and that mask-wearing is a vital public health tool, both in conjunction with and independent of other measures like vaccination and social distancing.

1 Nov 2023

Microscopic inflammation in IBD linked to higher risk of serious infections

Inflammatory bowel disease (IBD) is an independent risk factor for serious infection, even at very low levels of gastrointestinal inflammation.

1 Nov 2023

New insights into role of cholinergic centro-cingulate network in Parkinson's disease and normal aging

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, "Cholinergic centro-cingulate network in Parkinson disease and normal aging."

1 Nov 2023

Hospitalization and mortality risks from COVID-19 by age during SARS-CoV-2 Delta and Omicron variants’ predominance

Age-stratified hospitalization and mortality risks from incident SARS-CoV-2 infections.

1 Nov 2023

Influence of employment during COVID-19 on cognitive and motor functions among elders

The effects of employment on geriatric health during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak.

1 Nov 2023

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

The study reveals that introducing progerin, a protein associated with accelerated aging, into cellular models of Alzheimer's Disease (AD) can hasten the development of AD-related traits. This innovative approach offers a more efficient method for studying AD mechanisms, potentially accelerating the discovery of new treatments.

31 Oct 2023

How next-gen sequencing is changing antibody drug discovery

New study outlines how next-generation sequencing (NGS) and machine-learning methods can revolutionize antibody discovery, particularly against SARS-CoV-2. The research demonstrates that NGS provides greater epitopic and paratopic diversity, enabling more effective identification and prioritization of therapeutic antibodies.

31 Oct 2023

Unbiased proteomic analysis reveals fibroinflammatory landscape of the aging ovary

A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, "Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature."

31 Oct 2023

Understanding COVID-19 mortality in people with severe mental illness and different ethnicities

In a recent study published in the British Journal of Psychiatry, researchers evaluated mortality in individuals with severe mental illness (SMI) following COVID-19.

31 Oct 2023

COVID-19’s long reach: Some physical symptoms can persist up to two years post-diagnosis

Researchers investigated the prevalence rate of physical-type symptoms by the severity of acute COVID-19 beyond two years of diagnosis.

31 Oct 2023

Late nights and skipping breakfast linked to increased heart disease risk, especially in men

Late sleepers who skip breakfast face elevated risk for metabolic syndrome and cardiovascular disease, especially in men, according to a large-scale study. The effects vary by age and gender, pointing to the complex interactions between sleep patterns, eating habits, and heart health.

30 Oct 2023

Syndrome News and Research

Decoding long COVID, pathophysiology, epidemiology, diagnosis, and management

High-impact clinical trial results to be presented at ASN Kidney Week 2023

States reconsider religious exemptions for vaccinations in child care

Gene discovery sheds light on ovary development

Citrus compounds show zesty promise in type 2 diabetes management

New "Core Outcome Measure Set" developed to assess the severity and impact of Long COVID

Scientists determine structure of key protein in neuronal communication

UH researcher awarded $1.2 million grant to unravel mystery of Z-RNA

Biomarker discovery boosts long-COVID prediction accuracy to 78.5%

Masking up matters: High-quality studies confirm face masks significantly curb COVID-19 spread

Microscopic inflammation in IBD linked to higher risk of serious infections

New insights into role of cholinergic centro-cingulate network in Parkinson's disease and normal aging

Hospitalization and mortality risks from COVID-19 by age during SARS-CoV-2 Delta and Omicron variants’ predominance

Influence of employment during COVID-19 on cognitive and motor functions among elders

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

How next-gen sequencing is changing antibody drug discovery

Unbiased proteomic analysis reveals fibroinflammatory landscape of the aging ovary

Understanding COVID-19 mortality in people with severe mental illness and different ethnicities

COVID-19’s long reach: Some physical symptoms can persist up to two years post-diagnosis

Late nights and skipping breakfast linked to increased heart disease risk, especially in men

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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