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Sleep apnea during pregnancy linked to the development of hypertension and metabolic syndrome

In a new study published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine, researchers examined whether sleep disordered breathing (primarily obstructive sleep apnea) during pregnancy and in the years after delivery is associated with an increased risk for hypertension and metabolic syndrome.

12 Feb 2022

Hazards of persistent and new clinical sequelae caused by SARS-CoV-2 infection among elderly patients

A new study estimated the risk and hazards of persistent and new clinical sequelae of the SARS-CoV-2 infection among elderly patients (above 65 years or older) during the post-acute phase of the infection.

11 Feb 2022

COPD patients more compliant with COVID-19 restrictions in the UK

A new study reports on the tendency among COPD patients in the UK to practice social distancing, compared to the public at large, during the COVID-19 pandemic.

11 Feb 2022

The impact of COVID-19 on people with systemic autoimmune rheumatic diseases

A survey demonstrated that patients with systemic autoimmune rheumatic diseases commonly experience augmented disease severity and disrupted treatment regimens of disease-modifying antirheumatic drugs after acute COVID-19 course.

11 Feb 2022

Model shows booster doses and antiviral pills may enable relaxation of SARS-CoV-2 social distancing

Researchers suggest that social distancing could be relaxed in order to reduce the number of severe cases of COVID-19, rather than stop the transmission of the SARS-CoV-2.

11 Feb 2022

Challenges in safely deprescribing common anticholinergic drugs

Medications with anticholinergic properties have been consistently associated with a wide range of adverse outcomes for older adults including cognitive impairment, yet these drugs continue to be commonly prescribed for depression, urinary incontinence, irritable bowel syndrome and Parkinson's disease.

11 Feb 2022

SARS-CoV-2 nucleocapsid G215C variation may explain Delta severity

A new study shows that the SARS-CoV-2 nucleocapsid protein has unique properties that allow the virus to become more infective in the presence of certain mutations.

11 Feb 2022

Study investigates population immunity to SARS-CoV-2 through heterogenous pathways

A new study demonstrates COVID-19 vaccine-specific differences in the antibody responses and memory B-cell immunity in a sample population comprising of 197 vaccinated individuals in Mexico.

11 Feb 2022

New COVID-19 test can determine if individuals have been vaccinated, infected, both, or neither

Researchers have created a new T cell assay that allows discrimination of COVID-19 infection and vaccination, as well as the order in which these occurred.

11 Feb 2022

Direct oral anti-coagulants less likely to result in major bleeding after rare, fatal stroke

Direct oral anti-coagulant (anti-clotting) (DOAC) medications that target a single clotting factor work just as well to prevent future clots as the older, less-specific medication warfarin.

11 Feb 2022

Drugs used to increase insulin signaling may be effective therapeutic strategy for autism

Drugs to increase insulin signaling may be effective for treating autism say Lancaster University researchers, who have discovered how a genetic change impacts on insulin signaling and glucose metabolism in the brain.

10 Feb 2022

Study suggests SARS-CoV-2 Omicron showed increased household transmission and immune evasion in Norway

Researchers from Norway used contact tracing data to measure and compare the household secondary attack rate of the SARS-CoV-2 Omicron and Delta variants at a time of prominence of both variants in the country.

10 Feb 2022

Spillover of SARS-CoV-2 Omicron variant infection in white-tailed deer in New York

Researchers detected evidence for SARS-CoV-2 Omicron variant exposure in the white-tailed deer population inhabiting Staten Island in New York.

10 Feb 2022

Excess COVID-19 mortality in Eastern Europe linked to lower vaccination rates and weak implementation of regulations

Researchers assessed the association between excess COVID-19 mortalities with vaccination rate, and regulation enforcement, in Eastern European countries that witnessed high COVID-19 mortalities throughout 2021.

10 Feb 2022

Screening assays identify TMPRSS2 inhibitors from drug repurposing candidates useful as COVID-19 therapeutic

Researchers used an assay toolset for discovering new transmembrane protease serine 2 inhibiting drug repurposing candidates, that can be useful as therapeutics for COVID-19 treatment.

10 Feb 2022

Clinical severity of COVID-19 caused by SARS-CoV-2 variants and the effectiveness of mRNA vaccines against them

A recent study examined the clinical severity of the SARS-CoV-2 Alpha, Delta, and Omicron VOCs and compared vaccine effectiveness against each VOC.

10 Feb 2022

Neutralizing antibody ABP-310 found to be highly potent against SARS-CoV-2 variants including Omicron

In a new study, a team of researchers described the efficacy of ABP-310, a neutralizing antibody, against SARS-CoV-2 variants, including Omicron.

10 Feb 2022

Properties and pharmacokinetics an oral drug candidate for COVID-19 treatment

Researchers studied the preclinical PK) and in vitro ADME properties of GS-441524, a potential oral drug for COVID-19 treatment.

10 Feb 2022

Study explores protection against Omicron and Delta infections by COVID-19 vaccination and previous infection

A new study demonstrated that infection- and vaccine-induced protection induced by the primary COVID-19 vaccination was much reduced for the Omicron BA.1 infection compared to the Delta infection.

10 Feb 2022

Rapid generation and evaluation of an mRNA vaccine candidate specific to Omicron

A recent study demonstrated the development of a potential SARS-CoV-2 Omicron variant-specific mRNA vaccine candidate.

10 Feb 2022

Syndrome News and Research

Sleep apnea during pregnancy linked to the development of hypertension and metabolic syndrome

Hazards of persistent and new clinical sequelae caused by SARS-CoV-2 infection among elderly patients

COPD patients more compliant with COVID-19 restrictions in the UK

The impact of COVID-19 on people with systemic autoimmune rheumatic diseases

Model shows booster doses and antiviral pills may enable relaxation of SARS-CoV-2 social distancing

Challenges in safely deprescribing common anticholinergic drugs

SARS-CoV-2 nucleocapsid G215C variation may explain Delta severity

Study investigates population immunity to SARS-CoV-2 through heterogenous pathways

New COVID-19 test can determine if individuals have been vaccinated, infected, both, or neither

Direct oral anti-coagulants less likely to result in major bleeding after rare, fatal stroke

Drugs used to increase insulin signaling may be effective therapeutic strategy for autism

Study suggests SARS-CoV-2 Omicron showed increased household transmission and immune evasion in Norway

Spillover of SARS-CoV-2 Omicron variant infection in white-tailed deer in New York

Excess COVID-19 mortality in Eastern Europe linked to lower vaccination rates and weak implementation of regulations

Screening assays identify TMPRSS2 inhibitors from drug repurposing candidates useful as COVID-19 therapeutic

Clinical severity of COVID-19 caused by SARS-CoV-2 variants and the effectiveness of mRNA vaccines against them

Neutralizing antibody ABP-310 found to be highly potent against SARS-CoV-2 variants including Omicron

Properties and pharmacokinetics an oral drug candidate for COVID-19 treatment

Study explores protection against Omicron and Delta infections by COVID-19 vaccination and previous infection

Rapid generation and evaluation of an mRNA vaccine candidate specific to Omicron

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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