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Unlocking the power of lectins: BOA emerges as a potent weapon against all SARS-CoV-2 variants

Researchers discover that antiviral lectins like BOA can effectively inhibit SARS-CoV-2 and its variants by targeting spike glycans, opening doors for potential pan-coronavirus treatments. The study reveals that BOA's multivalent interactions make it a potent inhibitor against a range of viral variants, offering promise for future therapeutic strategies.

14 Sep 2023

Past infections may shape your COVID booster's punch against Omicron

This in-depth study examines how previous immunity impacts the effectiveness of COVID-19 booster vaccinations and susceptibility to Omicron breakthrough infections. The research highlights the significant role of individual immune histories in shaping both humoral and cellular responses to SARS-CoV-2, urging for more tailored vaccine strategies.

14 Sep 2023

Impact of prior SARS-CoV-2 infection and mRNA vaccination on contagiousness and infection risk

The study finds that natural SARS-CoV-2 infection offers stronger immunity against the virus compared to mRNA vaccines. However, mRNA vaccines significantly reduce the infectiousness of individuals with COVID-19, playing a crucial role in limiting the virus's transmission.

14 Sep 2023

Study reveals how a causal factor in Angelman syndrome eliminates neural chat

Researchers from the University of Tokyo reveal how the presynaptic Ube3a E3 ligase, a causal factor in Angelman syndrome, eliminates neural chat.

14 Sep 2023

NYU Langone doctors complete longest-documented case of pig kidney transplant in human body

After 61 days of observation, NYU Langone Health doctors this month completed the longest-documented case of a genetically engineered pig kidney functioning in a human body.

14 Sep 2023

Utilizing deep learning to enhance the accuracy of mortality forecasts in emergency rooms

Researchers enhanced the accuracy of mortality predictions in emergency departments by employing advanced data-synthesis techniques and machine-learning models.

14 Sep 2023

COVID-19 doubles risk of early type 1 diabetes signs in high-risk children

New research in JAMA finds a temporal association between SARS-CoV-2 infections and the onset of islet autoimmunity, a precursor to type 1 diabetes, in genetically predisposed infants. The study underscores COVID-19 as a potential risk factor for the development of this form of diabetes in young children.

13 Sep 2023

New Omicron subvariant BA.2.86: A master of immune escape but not taking over yet

Researchers have isolated a new SARS-CoV-2 Omicron subvariant, BA.2.86, revealing its ability to escape neutralizing antibodies five-fold greater than its ancestor strain. Despite its enhanced immune evasion capabilities, BA.2.86 has not shown a significant difference in spread compared to other current variants.

13 Sep 2023

Researchers develop new protocol to study white matter injury in Alzheimer's disease

A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 16, entitled, "Microvascular contributions to white matter injury in Alzheimer's disease."

13 Sep 2023

How COVID-19 targets the pancreas revealed

The study uncovers the role of the PLAC8 protein in making the human pancreas vulnerable to SARS-CoV-2 infection, leading to pancreatic injury and complications in severe COVID-19 cases. The findings open up new avenues for understanding how the virus affects multiple organ systems and offer a potential target for future treatments.

12 Sep 2023

Many 'mild' COVID patients still battling lung damage a year later

A recent PLoS ONE study reveals that severe COVID-19 patients are at higher risk of long-term pulmonary impairments, with nearly half experiencing reduced lung function a year after disease onset. The study underscores the need for ongoing monitoring to manage 'long COVID' symptoms effectively.

12 Sep 2023

SARS-CoV-2 infection can exacerbate production of auto-antibodies relating to auto-immune diseases

An article published in NPJ Aging, a Springer Nature journal, reveals that natural production of auto-antibodies increases with age and that infection by SARS-CoV-2 can exacerbate production of auto-antibodies relating to auto-immune diseases, helping to explain why aging increases the chances of developing severe COVID-19.

12 Sep 2023

Single-ventricle physiology correlates with higher short-term mortality among adult congenital heart disease transplant recipients

UCLA-led research finds that among adult congenital heart disease (CHD) transplant recipients, single-ventricle physiology correlated with higher short-term mortality.

12 Sep 2023

Mesenchymal stem cell-derived extracellular vesicles show promise in PCOS treatment

Polycystic ovary syndrome (PCOS) is a pervasive endocrine disorder that affects millions of women globally, impacting their hormonal balance, fertility and overall well-being.

12 Sep 2023

Is the coadministration of a COVID-19 vaccine with a seasonal influenza vaccine safe and efficacious?

Researchers investigated the comparative efficacy and safety of the simultaneous COVID-19 and seasonal influenza vaccination regimen compared to SARS-CoV-2 vaccination alone among healthcare workers who had received one or two COVID-19 booster doses.

12 Sep 2023

Groundbreaking discovery reveals how brain proteins can help alleviate DNA replication stress

A team of researchers from the Department of Biological Sciences at UNIST has achieved a significant breakthrough in understanding how brain proteins can help alleviate complications arising from DNA replication stress.

12 Sep 2023

The safety and efficacy of the nano-based COVID-19 vaccine

A recent study evaluated the safety and efficacy of the GBP510 vaccine against SARS-CoV-2 infection.

12 Sep 2023

What factors are associated with readmission in pediatric survivors of acute respiratory distress syndrome (ARDS)?

Researchers explore the rates of readmission over the first year among children who survived acute respiratory distress syndrome.

12 Sep 2023

Buck Institute receives $3.5 million federal grant to lead clinical trial of ketone intervention in older adults

The Buck Institute for Research on Aging has received a $3.5 million federal grant to lead the first-ever double-blind, randomized, placebo-controlled clinical trial to understand the effects of ketone ester supplementation on frailty, a condition of vulnerability which develops following age-related decline in multiple physiological systems.

11 Sep 2023

Can fluctuating reproductive hormone levels cause mental health conditions?

The association between mental health and fluctuations in reproductive hormone levels.

11 Sep 2023

Syndrome News and Research

Unlocking the power of lectins: BOA emerges as a potent weapon against all SARS-CoV-2 variants

Past infections may shape your COVID booster's punch against Omicron

Impact of prior SARS-CoV-2 infection and mRNA vaccination on contagiousness and infection risk

Study reveals how a causal factor in Angelman syndrome eliminates neural chat

NYU Langone doctors complete longest-documented case of pig kidney transplant in human body

Utilizing deep learning to enhance the accuracy of mortality forecasts in emergency rooms

COVID-19 doubles risk of early type 1 diabetes signs in high-risk children

New Omicron subvariant BA.2.86: A master of immune escape but not taking over yet

Researchers develop new protocol to study white matter injury in Alzheimer's disease

How COVID-19 targets the pancreas revealed

Many 'mild' COVID patients still battling lung damage a year later

SARS-CoV-2 infection can exacerbate production of auto-antibodies relating to auto-immune diseases

Single-ventricle physiology correlates with higher short-term mortality among adult congenital heart disease transplant recipients

Mesenchymal stem cell-derived extracellular vesicles show promise in PCOS treatment

Is the coadministration of a COVID-19 vaccine with a seasonal influenza vaccine safe and efficacious?

Groundbreaking discovery reveals how brain proteins can help alleviate DNA replication stress

The safety and efficacy of the nano-based COVID-19 vaccine

What factors are associated with readmission in pediatric survivors of acute respiratory distress syndrome (ARDS)?

Buck Institute receives $3.5 million federal grant to lead clinical trial of ketone intervention in older adults

Can fluctuating reproductive hormone levels cause mental health conditions?

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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