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Saliva samples may be reliable alternative to nasal swabs for SARS-CoV-2 testing

A team of researchers from various institutes in Switzerland report how saliva samples may be a strong alternative to nasal swaps in PCR-related SARS-CoV-2 testing.

8 Dec 2020

Study unveils struggles faced by surgical units during the COVID-19 pandemic

Researchers at the University of Calgary, Canada, shed light on how surgical services have been reorganized during and following the COVID-19 pandemic.

8 Dec 2020

Novel antibody-drug conjugate shows 29% response rate in rare blood cancer

Early study data shows a 29% overall response rate, the favorable safety profile in blastic plasmacytoid dendritic cell neoplasm (BPDCN)

8 Dec 2020

Researchers use novel technology to prevent destruction of specific proteins inside cells

Columbia researchers have created a new technology using synthetic llama antibodies to prevent specific proteins from being destroyed inside cells.

8 Dec 2020

Chemotherapy combined with blinatumomab increases survival for patients with Ph-negative B-ALL

A study led by The University of Texas MD Anderson Cancer Center showed that first-line treatment with a regimen of chemotherapy combined with the monoclonal antibody blinatumomab resulted in increased survival and achieved a high rate of measurable residual disease (MRD) negativity for patients who were newly diagnosed with a high-risk form of acute lymphoblastic leukemia (ALL) known as Philadelphia chromosome-negative B-cell ALL (Ph-negative B-ALL).

7 Dec 2020

Study finds CAR T cell therapy as effective as first-line treatment for high-risk large B-cell lymphoma

A study led by researchers at The University of Texas MD Anderson Cancer Center found that axi-cel, an autologous anti-CD19 chimeric antigen receptor (CAR) T cell therapy, is a safe and effective first-line therapy for patients with high-risk large B-cell lymphoma (LBCL), a group with an urgent need for new and effective treatments.

7 Dec 2020

How effective is social distancing in preventing SARS-CoV-2 transmission? A New York case study

A new study by researchers at the City University of Hong Kong examined the efficacy of non-pharmaceutical interventions (NPIs) on controlling the coronavirus disease 2019 (COVID-19) pandemic, the illness SARS-CoV-2 causes.

7 Dec 2020

Xylitol and grapefruit seed extract shows promise in preventing SARS-CoV-2 infection, study finds

A team of researchers at the Feinberg School of Medicine demonstrated that xylitol and grapefruit seed extract (GSE) could prevent SARS-CoV-2 infection. These can be used as a nasal spray to contain the spread of the coronavirus.

7 Dec 2020

The intranasal route of immunization may offer effective protection against SARS-CoV-2

Researchers at the School of Medicine, Washington University in Saint Louis, USA, showed that the intranasal route of immunization could provide a more efficient protection against SARS-CoV-2 compared to the intramuscular route (i.e. through ‘jabs’).

7 Dec 2020

Nearly 70% of diabetic patients in Indonesia experience disease management difficulties, study finds

Researchers from the Fatmawati General Hospital, Indonesia, recently determined the difficulties in diabetes management and how it impacts diabetes morbidity in Indonesia during the COVID-19 pandemic.

7 Dec 2020

Molecular simulations reveal that remdesivir targets two SARS-CoV-2 enzymes

Remdesivir has been shown to target both RNA-dependent RNA polymerase and main protease of SARS-CoV-2 – resulting in a ‘double whammy’ effect.

7 Dec 2020

Evolution of the SARS-CoV-2 proteome in 3D during the first six months of the COVID-19 pandemic

In a recent study, researchers report how the SARS-CoV-2 proteome in 3D has evolved during the first six months of the COVID-19 pandemic.

7 Dec 2020

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Clinical investigators from Hackensack Meridian Health John Theurer Cancer Center (JTCC), a member of the Georgetown Lombardi Comprehensive Cancer Center consortium, are to present updates on treatment advances in multiple myeloma (MM), mantle cell lymphoma (MCL), and other types of B-cell lymphoma (BCL) as well as leukemia at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, to be held virtually from December 5-8, 2020.

7 Dec 2020

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

The novel oral drug venetoclax can be safely added to standard therapies for some high-risk myeloid blood cancers and in early studies the combination shows promise of improved outcomes, say scientists from Dana-Farber Cancer Institute.

7 Dec 2020

Study: CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

A CAR T-cell therapy known as axicabtagene ciloleucel (axi-cel) drove cancer cells to undetectable levels in nearly 80% of patients with advanced non-Hodgkin lymphoma (NHL) in a phase 2 clinical trial.

6 Dec 2020

Crucial monitoring tools effective for assessment of patients with COVID-19

A combined research team from the Universities of Portsmouth and Bournemouth and Portsmouth Hospitals University NHS Trust has shown that an assessment score used to measure a patient's severity of illness can be applied to patients with Covid-19 without modification.

5 Dec 2020

Donor stem cell transplant can improve survival rates for older patients with MDS, study shows

A new clinical trial offers the most compelling evidence to date that a donor stem cell transplant can improve survival rates for older patients with higher-risk myelodysplastic syndrome (MDS), Dana-Farber Cancer Institute investigators report at the virtual 62nd American Society of Hematology Annual Meeting.

5 Dec 2020

Findings about primary cilia may be relevant for transplantation therapies in diabetes

A new study from Karolinska Institutet and the Helmholtz Diabetes Research Center shows that primary cilia, hair-like protrusions on endothelial cells inside vessels, play an important role in the blood supply and delivery of glucose to the insulin-producing beta cells in the pancreatic islets.

5 Dec 2020

New study finds link between gestational age and ADHD in children with Down syndrome

A new study by the UC Davis MIND Institute finds a connection between gestational age and attention deficit/hyperactivity disorder (ADHD) symptoms in children with Down syndrome.

4 Dec 2020

Study shows advantages of Mediterranean diet for patients with heart disease

A clinical study with 1002 patients with heart disease shows the advantages of a Mediterranean diet compared to a low-fat diet.

4 Dec 2020

Syndrome News and Research

Saliva samples may be reliable alternative to nasal swabs for SARS-CoV-2 testing

Study unveils struggles faced by surgical units during the COVID-19 pandemic

Novel antibody-drug conjugate shows 29% response rate in rare blood cancer

Researchers use novel technology to prevent destruction of specific proteins inside cells

Chemotherapy combined with blinatumomab increases survival for patients with Ph-negative B-ALL

Study finds CAR T cell therapy as effective as first-line treatment for high-risk large B-cell lymphoma

How effective is social distancing in preventing SARS-CoV-2 transmission? A New York case study

Xylitol and grapefruit seed extract shows promise in preventing SARS-CoV-2 infection, study finds

The intranasal route of immunization may offer effective protection against SARS-CoV-2

Nearly 70% of diabetic patients in Indonesia experience disease management difficulties, study finds

Molecular simulations reveal that remdesivir targets two SARS-CoV-2 enzymes

Evolution of the SARS-CoV-2 proteome in 3D during the first six months of the COVID-19 pandemic

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

Study: CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

Crucial monitoring tools effective for assessment of patients with COVID-19

Donor stem cell transplant can improve survival rates for older patients with MDS, study shows

Findings about primary cilia may be relevant for transplantation therapies in diabetes

New study finds link between gestational age and ADHD in children with Down syndrome

Study shows advantages of Mediterranean diet for patients with heart disease

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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