Synovial Fluid News and Research

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Mast cells in synovial tissue may explain why women report worse osteoarthritis pain than men

Investigators at Hospital for Special Surgery (HSS) have discovered that at the time of total knee replacement, women have significantly increased levels of immune cells called mast cells in synovial tissue surrounding the knee joint than men.

14 Nov 2022

Researchers explore single-cell sequencing technologies to understand molecular mechanisms of autoimmune diseases

A new review discussed the applications of single-cell ribonucleic acid sequencing (scRNA-seq) in understanding autoimmune disorders.

17 Oct 2022

Frequency domain optical imaging could reliably identify lupus arthritis and track disease progression

Systemic lupus erythematosus (SLE), commonly referred to as simply "lupus", is an autoimmune disorder where the body's immune system attacks healthy tissue.

26 Oct 2021

Researchers capture mechanisms for predicting cartilage degradation and recovery after ACL injury

Post-traumatic osteoarthritis is a musculoskeletal disorder shadowing especially the life of young and active population.

6 Oct 2021

Diagnosis of viral infections using micro and nanoscale technologies

In a recent study, the authors provide a review on both micro- and nanoscale technologies that advanced the diagnosis of viral diseases.

3 Aug 2021

3D-printed anatomical finger model offers procedural guidance of trigger finger injections

Treatment of an injured or diseased joint may require precise insertion of a syringe needle -- musculoskeletal sonography can help guide clinicians as they drain fluid from arthritic knees or inject corticosteroids into trigger fingers.

22 Apr 2021

Rice model could help clinicians personalize hip joints

Rice University engineers hope to make life better for those with replacement joints by modeling how artificial hips are likely to rub them the wrong way.

11 Jan 2021

Researchers identify the gene responsible for cellular aging

In a new study, published today in the journal Stem Cells, researchers reveal how they have identified the gene responsible for aging.

30 Nov 2020

Novel super-activating macrophage receptor could explain hyper-inflammation in severe COVID-19

Immunity is a curious thing. While essential in protecting the body against invading pathogens and foreign antigens, it can also turn against the body and trigger destructive immunological processes. A new study published on the preprint server bioRxiv* in November 2020 reports on the role played by hyperactive macrophages in a range of acute and chronic hyper-inflammatory conditions.

10 Nov 2020

Immunotherapy drugs trigger inflammatory arthritis in subset of cancer patients

Since doctors began treating cancer patients with immunotherapy drugs called checkpoint inhibitors nearly a decade ago, they have observed that a subset of these patients experience a side effect that clinically looks like inflammatory arthritis.

10 Nov 2020

Lateral flow test enables faster, accurate diagnosis of periprosthetic joint infection

The recently FDA-authorized alpha-defensin lateral flow test is a highly accurate, ten-minute test for diagnosis of periprosthetic joint infection (PJI) - a serious and costly complication of total joint replacement, reports a study in The Journal of Bone & Joint Surgery.

9 Nov 2020

Study shows how medicine can benefit from dinosaur research

Researchers from the University of Bonn: Even Tyrannosaurus rex could have suffered a slipped disc. The intervertebral discs connect the vertebrae and give the spine its mobility.

24 Aug 2020

Latest findings put Benson Viscometers at the forefront of Covid-19 fight

A clinical viscosity diagnostic instrument is proving to be valuable in the research and treatment of coronavirus after laboratory scientists have identified its ability to provide meaningful data for medical teams treating Covid-19 patients.

3 Jul 2020

Virginia Tech researcher wins $661,216 grant to study Lyme arthritis

With a $661,216 grant from the Steven & Alexandra Cohen Foundation, Brandon Jutras, an assistant professor of biochemistry in the Virginia Tech College of Agriculture and Life Sciences, will study Lyme arthritis, including the cellular component that contributes to it.

22 May 2020

Methotrexate reduces joint damage in hand osteoarthritis

A new study presented at the 2019 ACR/ARP meeting shows that methotrexate stopped further damage to the hand joints and even perhaps improved bone remodeling in patients with osteoarthritis (OA) of the hand, when they were assessed at 3 and 12 months.

11 Nov 2019

Antibody that targets CXCR6 prevents and reverses multiple sclerosis in mouse model

Multiple sclerosis, an autoimmune disorder, is known to be driven by "helper" T cells, white blood cells that mount an inflammatory attack on the brain and spinal cord. A new study from Boston Children's Hospital pinpoints the specific subgroup of helper T cells that cause MS, as well as a protein on their surface, called CXCR6, that marks them.

4 Oct 2019

Synovial Fluid News and Research

Mast cells in synovial tissue may explain why women report worse osteoarthritis pain than men

Researchers explore single-cell sequencing technologies to understand molecular mechanisms of autoimmune diseases

Frequency domain optical imaging could reliably identify lupus arthritis and track disease progression

Researchers capture mechanisms for predicting cartilage degradation and recovery after ACL injury

Diagnosis of viral infections using micro and nanoscale technologies

3D-printed anatomical finger model offers procedural guidance of trigger finger injections

Rice model could help clinicians personalize hip joints

Researchers identify the gene responsible for cellular aging

Novel super-activating macrophage receptor could explain hyper-inflammation in severe COVID-19

Immunotherapy drugs trigger inflammatory arthritis in subset of cancer patients

Lateral flow test enables faster, accurate diagnosis of periprosthetic joint infection

Study shows how medicine can benefit from dinosaur research

Latest findings put Benson Viscometers at the forefront of Covid-19 fight

Virginia Tech researcher wins $661,216 grant to study Lyme arthritis

Methotrexate reduces joint damage in hand osteoarthritis

Antibody that targets CXCR6 prevents and reverses multiple sclerosis in mouse model

Joint lubricating fluid triggers pain response from nerve cells in osteoarthritic patients

New, quantitative method for assessment of molecular biomarker for osteoarthritis

Galectins play a key role in the degeneration of cartilage in osteoarthritis

OrthoSera presents first-in-man study results of hyperacute serum in knee osteoarthritis

The Incredible Potential of Lipid Nanoparticles (LNPs)

Hasret Altan-Martin

Speeding Up Sample Preparation to Accelerate Analytical Chemistry

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