Systemic Inflammatory Response Syndrome News and Research

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Scientists find new way to significantly reduce detection time for sepsis

What do Casey Kasem, Christopher Reeve and Muhammad Ali have in common? They all died of sepsis: a rapid, potentially deadly reaction that affects about 1 million Americans each year.

1 Nov 2016

VIB-Ghent University research provides insights into septic shock

Researchers at VIB and Ghent University have discovered an important mechanism of sepsis, an overreaction of the body's immune system to an infection.

14 Sep 2016

Implementation of value-driven outcomes tool in health care system can lead to lower costs, better quality

Implementing an analytic tool that allocates clinical care costs and quality measures to individual patient encounters was associated with significant improvements in value of care for 3 designated outcomes—total joint replacement, laboratory testing among medical inpatients, and sepsis management, according to a study appearing in the September 13 issue of JAMA.

14 Sep 2016

New test may help predict sepsis risk in patients with severe burn injuries

Birmingham researchers have created a potentially life-saving new test that will allow clinicians to predict which burn victims will develop sepsis during their treatment.

29 Jun 2016

Automated process uses EMR to identify patients with potential for clinical deterioration

Hospitalized patients can deteriorate quickly, requiring prompt identification and treatment, especially since each hour of treatment delay can increase the risk of mortality.

17 May 2016

Research shows spleen MZ B cells produce signaling proteins involved in inflammatory responses

The inability to adequately respond to infection can cause a whole-body state of inflammation known as sepsis. This can eventually lead to systemic inflammatory response syndrome (SIRS), and even death.

9 May 2016

Secondary non-Hodgkin's lymphoma a concern for CML patients using TKIs

Patients with chronic myeloid leukaemia who use the tyrosine kinase inhibitor imatinib may be three to four times more likely to develop non-Hodgkin's lymphoma than the general population, study findings indicate.

17 Mar 2016

Two-stage CDS system reduces risk of adverse outcomes for sepsis patients

Sepsis is an inflammatory response to infection that's known to develop in hospital settings and can turn deadly when it's not discovered early on. In a new study, a hospital surveillance program focusing on reducing the risks of sepsis, known as the two-stage Clinical Decision Support (CDS) system, was found to reduce the risk of adverse outcomes, such as death and hospice discharge for sepsis patients, by 30% over the course of one year.

22 Oct 2015

Cell transplantation researchers successfully treat laboratory rats modeled with severe burns

Cell transplantation researchers have successfully used bone marrow-derived mesenchymal stromal cells (MSCs) to treat a variety of diseases and conditions. Now, using injections of MSCs, a research team in Brazil has successfully treated laboratory rats modeled with severe burns.

25 Jun 2015

Researchers discover that extreme exercise can lead to blood poisoning

Researchers have discovered that extreme exercise can cause intestinal bacteria to leak into the bloodstream, leading to blood poisoning.

17 Jun 2015

New model explains how immune cells recognize, destroy bacteria

The innate immune system serves as the body's specialized armed forces division, comprised of a host of defense mechanisms used to battle bacterial infections. Among the system's warriors are white blood cells including the specialized macrophages, which maintain constant surveillance for foreign intruders or pathogens, functioning as the body's first line of defense, poised to attack at barrier sites including the skin, lungs and intestines.

11 Nov 2014

First publication describing use of CytoSorb during cardiac surgery

CytoSorbents Corporation, a critical care immunotherapy company commercializing its CytoSorb® cytokine adsorber in multiple countries worldwide, announced the PDF availability of the first publication describing the use of CytoSorb® intra-operatively during cardiac surgery at the Ludwig Maximilian University of Munich Hospital - Grosshadern Campus, in Germany.

17 Jul 2014

New antibiotic proves effective in treating serious bacterial skin and skin-structure infections

A study published in today's New England Journal of Medicine reports that the antibiotic dalbavancin is as effective as vancomycin, the current standard-of-care antibiotic used to treat serious bacterial skin and skin-structure infections.

5 Jun 2014

Landes Bioscience releases special issue on sepsis

A special issue on sepsis has been released by the publisher Landes Bioscience (Austin, TX USA). The articles contained in this special issue of the journal Virulence have been authored by world-class investigators and provide new insights into both the pathogen-related factors and the host defense mechanisms that lead to septic shock and contribute to its resolution or fatal outcome.

7 Jan 2014

King's College researchers identify new biomarker that detects sepsis in blood

Researchers at King's College London have identified a biomarker - a biological 'fingerprint' - for sepsis in the blood, and showed it could be possible to diagnose the condition within two hours by screening for this biomarker at a patient's bedside.

17 Oct 2013

Updated guidelines for management of acute pancreatitis

Updated guidelines on the management of acute pancreatitis, a condition that causes acute inflammation of the pancreas, appear in the September issue of The American Journal of Gastroenterology.

5 Sep 2013

AACN adds research reviews from Cochrane Collaboration in Critical Care Nurse journal

The American Association of Critical-Care Nurses adds research reviews from The Cochrane Collaboration as a regular department in its clinical practice journal, Critical Care Nurse.

2 Aug 2013

Researchers identify novel biomarkers for predicting mortality in ICU patients

A metabolic profile of intensive care unit patients based on biomarkers of four metabolites can be used to accurately predict mortality, according to a new study.

21 May 2013

World Trade Center rescue workers may face increased cancer risk

People who were involved in the rescue and recovery operation at the World Trade Center are at an increased risk for certain types of cancer, including prostate, thyroid, and myeloma, study findings suggest.

31 Dec 2012

Study finds increased risk of cancers among rescue/recovery workers after WTC terrorist attack

Among rescue and recovery workers exposed to the dust, debris, and fumes following the World Trade Center terrorist attack, there was an increased incidence of prostate and thyroid cancers and multiple myeloma, although it is not clear how big a factor medical screening and non-WTC risk factors contributed to these increases, according to a study in the December 19 issue of JAMA.

21 Dec 2012