Tau Protein News and Research

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Tau proteins are microtubule-associated proteins found in neurons in the brain.

Blood-based markers could lead to earlier detection of Alzheimer's disease

Alzheimer's disease begins decades before any symptoms, such as memory loss, start to show. Consequently, early diagnosis increases the chances of slowing the disease down with drugs.

10 Jan 2023

Targeting defective tau proteins may be needed to treat Alzheimer’s patients

In November, researchers reported the drug lecanemab slowed the progression of Alzheimer's disease. The effect was modest, but it has generated tremendous excitement because it was the first time a drug had been shown to be able to affect the course of this relentless, incurable disease.

26 Dec 2022

Breached dolphin's brains show neuropathology similar to Alzheimer's

In a new European Journal of Neuroscience study, scientists studied the brains of Odontocetes (Toothed whales) to document the presence or absence of neuropathological hallmarks of AD.

25 Dec 2022

The distinct pathophysiology of ‘SuperAger’ brains

Superagers are adults over the age of 80 who have a superior memory capacity that resembles that of middle-aged adults.

27 Nov 2022

New biomarker can help identify people with a primary tauopathy

Zooming in on a single disease and studying it intensely is often the most productive route to finding treatments. But there's no easy way to distinguish among people living with any of the primary tauopathies -; a group of rare brain diseases marked by rapidly worsening problems with thinking and movement -; because the symptoms are too similar.

24 Nov 2022

Key Alzheimer’s gene alters the way cholesterol moves around the brain, research finds

A gene recognized as the strongest risk factor for Alzheimer's disease (AD) alters the way cholesterol moves around the brain and as we age, this altered movement likely contributes to loss of learning and memory, a team of researchers from the Icahn School of Medicine at Mount Sinai and the Massachusetts Institute of Technology reports.

16 Nov 2022

New biomarker could aid in early diagnosis of Alzheimer’s disease

A definitive diagnosis of Alzheimer's disease (AD) was once only possible after someone had died, but recent biomarker studies have led to the development of imaging and spinal fluid tests for those still living.

9 Nov 2022

Green tea catechins and resveratrol display neuroprotective properties in Alzheimer's models

In a recent study published in the journal Free Radical Biology and Medicine, researchers screened for neuroprotective compounds against Alzheimer’s disease (AD).

3 Nov 2022

Exploring new therapeutic targets and biomarkers for neurodegenerative disorders

In this interview, Dr. Shebna Massey discusses neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and more. She also discusses and explores new therapeutic targets and biomarkers for these diseases.

From Sino Biological Inc. 26 Oct 2022

Newly identified mechanism may explain why women are more vulnerable to Alzheimer's disease

Case Western Reserve University researchers have identified a mechanism in brain tissue that may explain why women are more vulnerable to Alzheimer's disease-;a finding that they say could help lead to new medicines to treat the disease.

4 Oct 2022

Cycles of fasting-mimicking diet appear to reduce signs of Alzheimer’s in mice

Cycles of a diet that mimics fasting appear to reduce signs of Alzheimer's in mice genetically engineered to develop the illness, according to a new USC Leonard Davis School of Gerontology-led study.

27 Sep 2022

In vivo imaging of α-synuclein aggregates in the brains of living patients with multiple system atrophy

α-synuclein is a neuronal protein involved in functions like vesicle trafficking and neurotransmitter release. It is typically found in abundance in a healthy brain.

30 Aug 2022

UC Davis research reveals a novel role for how tau functions in healthy nerve cells

In Alzheimer's Disease and other neurodegenerative dementias, proteins that normally play a role in healthy brain tissue turn bad, clumping together to form insoluble plaques and tangles as neurons wither and die.

25 Aug 2022

UC San Diego receives $1.3 million grant to understand the role of misfolded tau proteins in dementia

Researchers at the University of California San Diego have received a $1.3 million grant from the W. M. Keck Foundation for a project that could help scientists better understand the role misfolded tau proteins play in causing neurodegenerative diseases like dementia, which may lead to more effective drug therapies.

16 Aug 2022

The safety and preliminary efficacy of OP-101 in patients with severe COVID-19

Researchers assessed the impact of dendrimer nanotherapy in treating severe COVID-19.

8 Aug 2022

The Alzheimer’s Association recognizes seven researchers for contributions to the field of dementia science

The Alzheimer’s Association will present seven awards at the Alzheimer’s Association International Conference 2022, recognizing researchers for their varied expertise, noteworthy achievements and innovative contributions to the field of Alzheimer’s and dementia science.

1 Aug 2022

Phase 2a clinical trial describes safety and efficacy of dendrimer nanotherapy in severe COVID-19 patients

A multicenter, randomized, placebo-controlled phase 2a clinical trial has recently been conducted to evaluate the efficacy of a nanotherapeutic compound OP-101 in treating severe COVID-19 patients.

21 Jul 2022

New center aims to accelerate research into biomarkers of neurodegenerative diseases

A new center established at Washington University School of Medicine in St. Louis aims to accelerate research into biomarkers of neurodegenerative conditions such as Huntington's and Parkinson's diseases, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS) and the so-called tauopathies, a group that includes Alzheimer's disease along with rarer diseases such as frontotemporal dementia, corticobasal syndrome and progressive supranuclear palsy.

13 Jul 2022

Study shows how tau protein, critical to Alzheimer's, turns from normal to diseased state

Alzheimer’s disease, the most common form of dementia, currently has no cure or effective therapy, in part due to gaps in our understanding of how the progressive neurodegenerative disorder arises in the brain.

8 Jul 2022

Elevated cerebrospinal fluid biomarkers of neuroinflammation in NeuroCOVID patients

A new research paper studied several biomarkers associated with neuronal injury, neuroinflammation, and neurodegeneration in NeuroCOVID adults who experienced a CNS syndrome during acute SARS-CoV-2 infection.

4 Jul 2022