Telomerase News and Research

RSS

LineaRx signs agreement with Takis/Evvivax to develop linear-DNA based anti-cancer vaccines

Applied DNA Sciences Inc. announced today that LineaRx, Inc., its wholly-owned subsidiary focused on next-generation biotherapeutics, has signed a Joint Development Agreement with Takis S.R.L. and Evvivax S.R.L., biotechnology companies focused on the discovery and development of DNA based anti-cancer vaccines for the human and animal markets, respectively.

20 Sep 2018

Researchers uncover secret of immortality mechanism in aggressive glioblastoma

UC San Francisco researchers have discovered how a mutation in a gene regulator called the TERT promoter -- the third most common mutation among all human cancers and the most common mutation in the deadly brain cancer glioblastoma -- confers "immortality" on tumor cells, enabling the unchecked cell division that powers their aggressive growth.

10 Sep 2018

RUDN biochemists describe previously unknown mechanism of autoimmunity regulation

The ability of a human body to resist pathogenic factors is under control of immune cells, the most important of which are lymphocytes.

7 Sep 2018

Gene therapy with telomerase does not increase cancer risk, study shows

Negative results and findings in science are perhaps less newsworthy, but they are no less important. Particularly when, as in this case, they demonstrate that a possible new therapeutic pathway against idiopathic pulmonary fibrosis and other diseases associated to short telomeres is in fact safe.

21 Aug 2018

Inhibition of NOVA1 gene helps prevent growth of lung cancer tumors

Researchers have identified a gene that when inhibited or reduced, in turn, reduced or prevented human non-small cell lung cancer tumors from growing.

7 Aug 2018

UCLA researchers have blueprint of telomerase that plays major role in cancer, aging

Cancer, aging-related diseases and other illnesses are closely tied to an important enzyme called "telomerase." UCLA researchers report in the journal Cell the deepest scientific understanding yet of this once-mysterious enzyme, whose catalytic core -- where most of its activity occurs -- can now be seen in near atomic resolution.

7 Jun 2018

Scientists disrupt two enzymes to shrink cancer cells

Before cell division, the long strings of the cell's DNA are wrapped tightly into the structures we know as chromosomes. This protects the cell's genetic material from physical and chemical damage.

17 May 2018

Telomerase discovery paves way for drugs to combat aging and cancer

Researchers have published the first detailed image of the molecular structure of human telomerase, the enzyme that lengthens chromosomes and extends the lifespan of a cell.

27 Apr 2018

Researchers target telomerase for killing NRAS-mutant melanoma cells

Targeting telomerase was effective at killing NRAS-mutant melanoma cells, and the impact was further enhanced when the strategy was paired with an inhibitor of mitochondrial function, according to study results by The Wistar Institute published in Oncogene.

26 Apr 2018

Study reports promising novel approach to treat therapy resistant pediatric brain tumors

Researchers used an experimental molecular therapy in preclinical laboratory tests to effectively treat several types of deadly pediatric brain cancer and now propose advancing the treatment to clinical testing in children.

17 Apr 2018

CNIO researchers determine structure of protein complex related to cell survival

A team from the Spanish National Cancer Research Centre has determined for the first time the high-resolution structure of a complex (R2TP) involved in key processes for cell survival and in diseases such as cancer.

16 Apr 2018

Targeting aberrantly active telomerase to treat therapy-resistant melanoma

A study conducted at The Wistar Institute in collaboration with The University of Texas Southwestern Medical Center has demonstrated the efficacy of targeting aberrantly active telomerase to treat therapy-resistant melanoma.

21 Mar 2018

Telomere length testing can alter treatment decisions for certain diseases

Research led by Johns Hopkins physicians and scientists shows that a test for measuring the length of DNA endcaps, called telomeres, which has a variability rate of 5 percent, can alter treatment decisions for patients with certain types of bone marrow failure.

27 Feb 2018

Telomerase News and Research

LineaRx signs agreement with Takis/Evvivax to develop linear-DNA based anti-cancer vaccines

Researchers uncover secret of immortality mechanism in aggressive glioblastoma

RUDN biochemists describe previously unknown mechanism of autoimmunity regulation

Gene therapy with telomerase does not increase cancer risk, study shows

Inhibition of NOVA1 gene helps prevent growth of lung cancer tumors

UCLA researchers have blueprint of telomerase that plays major role in cancer, aging

Scientists disrupt two enzymes to shrink cancer cells

Telomerase discovery paves way for drugs to combat aging and cancer

Researchers target telomerase for killing NRAS-mutant melanoma cells

Study reports promising novel approach to treat therapy resistant pediatric brain tumors

CNIO researchers determine structure of protein complex related to cell survival

Targeting aberrantly active telomerase to treat therapy-resistant melanoma

Telomere length testing can alter treatment decisions for certain diseases

ASU researchers uncover crucial step in telomerase enzyme catalytic cycle

CAR-T therapy saves life of cancer researcher

Researchers develop gene therapy for idiopathic pulmonary fibrosis

Researchers use gene therapy that lengthens telomeres to cure pulmonary fibrosis in mice

Simple molecular test may help predict presence of high-grade pancreatic cancers

Study paves way for new therapeutic strategies to impede growth of virus-induced cancers

Russian scientists uncover previously unknown effect of leukemia drug

One Health, One Mission: The World Organisation for Animal Health on the AMR Frontline

Uniting Against Resistance: The World Health Organization for World Antimicrobial Awareness Week 2023

Tackling Antimicrobial Resistance: A Conversation with Dr. Beverley Isherwood

Latest News