Dramatic advances in the fields of biochemistry, cell and molecular biology, genetics, biomedical engineering and materials science have given rise to the remarkable new cross-disciplinary field of tissue engineering. Tissue engineering uses synthetic or naturally derived, engineered biomaterials to replace damaged or defective tissues, such as bone, skin, and even organs.
A new study has demonstrated the tissue regenerative potential of a chemoattractant delivery system that can draw mesenchymal stem cells (MSCs) to the site of intervertebral disc (IVD) degeneration.
Researchers have developed a novel tool for determining the sensitivity of bone healing to inhibition of the Wnt signaling pathway and have validated its use in a study of bone regeneration in mice.
Cherwell Laboratories, supplier of environmental monitoring and process validation products, has confirmed its continued support for the Pharmaceutical & Healthcare Sciences Society - UCL Q3P Annual Conference 2018.
A new biosensor allows researchers to track oxygen levels in real time in "organ-on-a-chip" systems, making it possible to ensure that such systems more closely mimic the function of real organs.
Formation of new blood vessels, a process also known as angiogenesis, is one of the major clinical challenges in wound healing and tissue implants. To address this issue, researchers from Texas A&M University have developed a clay-based platform to deliver therapeutic proteins to the body to assist with the formation of blood vessels.
Researchers from The Hong Kong Polytechnic University have designed and fabricated a high performing self-fitting bone scaffold by combining a shape memory foam and hydroxyapatite (the principal mineral component of bone tissue).
A study of a large animal model of achromatopsia caused by a mutation in the CNGA3 gene that was treated with a single injection of CNGA3 gene therapy delivered using an AAV5 vector revealed findings reported long-term follow-up findings that show promise for the efficacy and safety of this therapeutic approach.
Platelet-rich plasma is believed to provide pain relief and help improve joint function in degenerative joint disease, but a new study has shown that it does not act by promoting stem cell proliferation or enhance the cartilage formation capabilities of mesenchymal stem cells
Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed a drug-delivery system that allows rapid response to heart attacks without surgical intervention.
Tissue engineering is the future of medicine. Under Project 5-100, the Polymer Materials for Tissue Engineering and Transplantology Laboratory of Peter the Great St. Petersburg Polytechnic University created unique polymeric materials for medical purposes that repair traumatized human organs.
Chemically coated, ceramic implants successfully guided the regrowth of missing bone in lab animals while "steadily dissolving," researchers report.
Scientists from the New York Stem Cell Foundation Research Institute have developed a new bone engineering technique called Segmental Additive Tissue Engineering.
Researchers have developed a bone engineering technique that uses stem cells to improve bone grafts for the treatment of bone injury or disease.
The Carl R. Woese Institute for Genomic Biology at the University of Illinois at Urbana-Champaign has purchased an EnvisionTEC 3D-Bioplotter to conduct regenerative biology and tissue engineering research
The National Institutes of Health is funding the research of a University of Akron scientist that could lead to more effective cancer treatment.
The intersection of graphene with stem cell biology may one day lead to new treatments for osteoarthritis, say researchers at Boise State University. Impacting millions of people across the globe, osteoarthritis is the most prevalent form of arthritis.
To help prevent possible complications such as nonunion at large fracture sites, researchers have developed a cartilage matrix that mimics the early stages of repair and provides the essential structural and biological properties needed by bone-forming cells to divide and grow.
Tissue-engineered articular cartilage for repairing cartilage damaged by trauma or disease can be made to more closely mimic natural AC if mechanical stimulation of particular magnitude and duration is applied during the development process.
Recently, a research team led by Dr. DU Xuemin at the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences created a new shape-morphing scaffold, enabling programmed deformation from a 2D planar cell-laden structure to a well-defined 3D tubular shape, which facilitated the facile 3D endothelialization of small-diameter vascular grafts.
Focal adhesions are large specialized proteins that are located in the area where a cell membrane meets the extracellular matrix, a collection of molecules surrounding the cells that provide support and regulate micromechanical signals to the cells.