Dramatic advances in the fields of biochemistry, cell and molecular biology, genetics, biomedical engineering and materials science have given rise to the remarkable new cross-disciplinary field of tissue engineering. Tissue engineering uses synthetic or naturally derived, engineered biomaterials to replace damaged or defective tissues, such as bone, skin, and even organs.
The dream of tissue engineering is a computer-controlled manufacturing of complex and functional human tissue for potential organ regeneration or replacement.
Medical practitioners routinely outfit patients with devices ranging from cardiovascular stents, pacemakers, catheters, and therapeutic lenses to orthopedic, breast, dental, and cochlear implants and prostheses.
According to the World Health Organization, cardiovascular disease has become the leading cause of death worldwide. However, vascular regeneration is a promising treatment for cardiovascular disease. Remodeling the endothelium - i.e., forming a confluent vascular endothelial cell monolayer on the lumen - plays a vital role in this process.
Researchers from the University of São Paulo in Brazil have developed a strategy for treating the most aggressive type of brain cancer in adults that combines a photoactive molecule and a chemotherapeutic agent - both encapsulated in protein-lipid nanoparticles.
A new study has shown that frailty is an important predictor of worse outcome after traumatic spinal cord injury in patients less than 75 years of age. In patients younger than 75 years, frailty was a predictor of adverse events, acute length of stay, and in-hospital mortality, as reported in an article published in Journal of Neurotrauma, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.
Repairing and reusing plastics and delivering cancer drugs more effectively are only two of many of the potential applications a new 3D/4D printing technology might have, thanks to the pioneering work of a research collaboration between UNSW Sydney and The University of Auckland.
Researchers at Rensselaer Polytechnic Institute have developed a way to 3D print living skin, complete with blood vessels. The advancement, published online today in Tissue Engineering Part A, is a significant step toward creating grafts that are more like the skin our bodies produce naturally.
Research into new endogenous mechanisms of tissue regeneration is an innovative research avenue in cardiac regeneration.
The brain is a complex organ full of neurons that work together to help us move, feel, think, and more. A multidisciplinary group from the University of Pittsburgh and Carnegie Mellon University is working to expand the amount of information researchers can receive from a neural interface device and received two grants from the National Science Foundation for their collaborative effort.
Researchers are making great strides toward developing gene-based strategies to treat a variety of inherited neurometabolic diseases characterized by severe neurological involvement.
Formlabs, the designer and manufacturer of powerful and accessible 3D printing systems, has released a user story with Dr Sam Pashneh-Tala, Research Fellow at the University of Sheffield, who is leading pioneering tissue engineering techniques for creating complex artificial blood vessels with patient-specific shapes, powered by Formlabs SLA 3D printers.
A team of Tufts University-led researchers exploring the development of cultured meat found that the addition of the iron-carrying protein myoglobin improves the growth, texture and color of bovine muscle grown from cells in culture.
Modern advances in oncology have significantly improved cancer survival rates. However, personalized treatment methods are necessary, since tumors may behave differently for different patients.
A biomedical engineering professor at Binghamton University, State University of New York is trying to find a cure for diabetes from several different angles, and three federal grants totaling nearly $1.2 million will aid her and her research team in that quest.
Move over, salamanders, we humans can also regrow some of our body tissues. At least, this is what a new study published on October 9, 2019, in the journal Science Advances, reports. Using a mechanism quite similar to that by which amphibians like salamanders, and some zebrafish, grow back lost body parts, human joint cartilage can also regenerate itself.
A microelectrode array is an implantable device through which neural signals can be obtained or delivered.
A team of Tufts University-led researchers has developed three-dimensional human tissue culture models of pediatric and adult brain cancers in a brain-mimicking microenvironment, a significant advancement for the study of brain tumor biology and pharmacological response.
Using light to facilitate the formation of new blood vessels: it is the breakthrough outcome of a research study carried out by researchers at Istituto Italiano di Tecnologia in Milan (Italy). The study was published in Science Advances.
Organs, muscles and bones are composed of multiple types of cells and tissues that are carefully organized to carry out a specific function.
Labnatek launches the first Polish company delivering additive technologies and high-resolution imaging techniques for the biotech and the healthcare sectors.