Dramatic advances in the fields of biochemistry, cell and molecular biology, genetics, biomedical engineering and materials science have given rise to the remarkable new cross-disciplinary field of tissue engineering. Tissue engineering uses synthetic or naturally derived, engineered biomaterials to replace damaged or defective tissues, such as bone, skin, and even organs.
The planarian flatworm is a simple animal with a mighty and highly unusual ability: it can regenerate itself from nearly every imaginable injury, including decapitation. These tiny worms can regrow any missing cell or tissue -- muscle, neurons, epidermis, eyes, even a new brain.
A new method to produce vaccines that have a longer shelf-life, are cheaper and can be stored without the need for cooling is being presented in the open access journal BMC Biotechnology.
A patient-specific tumor organoid platform developed by Wake Forest Institute for Regenerative Medicine researchers and their cancer center colleagues could someday take the guessing game out of immunotherapy treatments.
Infections are a dreaded threat that can have fatal consequences after an operation, in the treatment of wounds, and during tissue engineering.
The Akay Lab biomedical research team at the University of Houston is reporting an improvement on a microfluidic brain cancer chip previously developed in their lab.
Boston researchers have developed a new way to generate groups of intestinal cells that can be used, among others, to make disease models in the lab to test treatments for diseases affecting the gastrointestinal system.
In a radical new approach to treat cocaine addition, researchers at the Mayo Clinic are seeking approval for first-in-human studies of a single-dose gene therapy.
A new study shows the feasibility of using gene therapy to treat the progressive neurodegenerative disorder chronic traumatic encephalopathy.
Researchers led by engineers at Tufts University have developed a novel, significantly more efficient fabrication method for silk that allows them to heat and mold the material into solid forms for a wide range of applications, including medical devices.
Someday, doctors would like to grow limbs and other body tissue for soldiers who have lost arms in battle, children who need a new heart or liver, and many other people with critical needs.
One of the tests that almost every patient must face before a surgery or other health intervention is an electrocardiogram.
The dream of tissue engineering is a computer-controlled manufacturing of complex and functional human tissue for potential organ regeneration or replacement.
Medical practitioners routinely outfit patients with devices ranging from cardiovascular stents, pacemakers, catheters, and therapeutic lenses to orthopedic, breast, dental, and cochlear implants and prostheses.
According to the World Health Organization, cardiovascular disease has become the leading cause of death worldwide. However, vascular regeneration is a promising treatment for cardiovascular disease. Remodeling the endothelium - i.e., forming a confluent vascular endothelial cell monolayer on the lumen - plays a vital role in this process.
Researchers from the University of São Paulo in Brazil have developed a strategy for treating the most aggressive type of brain cancer in adults that combines a photoactive molecule and a chemotherapeutic agent - both encapsulated in protein-lipid nanoparticles.
A new study has shown that frailty is an important predictor of worse outcome after traumatic spinal cord injury in patients less than 75 years of age. In patients younger than 75 years, frailty was a predictor of adverse events, acute length of stay, and in-hospital mortality, as reported in an article published in Journal of Neurotrauma, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.
Repairing and reusing plastics and delivering cancer drugs more effectively are only two of many of the potential applications a new 3D/4D printing technology might have, thanks to the pioneering work of a research collaboration between UNSW Sydney and The University of Auckland.
Researchers at Rensselaer Polytechnic Institute have developed a way to 3D print living skin, complete with blood vessels. The advancement, published online today in Tissue Engineering Part A, is a significant step toward creating grafts that are more like the skin our bodies produce naturally.
Research into new endogenous mechanisms of tissue regeneration is an innovative research avenue in cardiac regeneration.
The brain is a complex organ full of neurons that work together to help us move, feel, think, and more. A multidisciplinary group from the University of Pittsburgh and Carnegie Mellon University is working to expand the amount of information researchers can receive from a neural interface device and received two grants from the National Science Foundation for their collaborative effort.