Transcatheter Aortic Valve Replacement News and Research

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High-risk surgical patients with severe aortic stenosis can benefit from new TAVR system

The Portico IDE study found that 30-day safety and one-year effectiveness outcomes of a novel self-expanding transcatheter aortic valve replacement (TAVR) system for patients with severe aortic stenosis (AS) at high or extreme-risk for surgery was noninferior to contemporary FDA-approved TAVR systems available in the United States.

30 Sep 2019

Researchers explore remodeling of cardiac tissues post-aortic valve replacement

University of Colorado Boulder engineers and faculty from the Consortium for Fibrosis Research & Translation at the University of Colorado Anschutz Medical Campus have teamed up to develop biomaterial-based "mimics" of heart tissues to measure patients' responses to an aortic valve replacement procedure, offering new insight into the ways that cardiac tissue re-shapes itself post-surgery.

12 Sep 2019

Catheter-based valve replacement procedure safe for patients with common heart defect

A new analysis conducted by investigators at the Cedars-Sinai Smidt Heart Institute shows for the first time that patients with a common heart defect who undergo catheter-based valve replacement procedures have the same survival and complication rates as patients without the defect who undergo the same procedure.

12 Jun 2019

Less invasive valve replacement can be safe and effective alternative for healthier patients

A new study by a team of cardiologists at Beth Israel Deaconess Medical Center led by senior and corresponding author Jeffrey Popma, MD, suggests that a minimally invasive procedure currently reserved for patients too frail to undergo surgery may in fact be a safe and effective alternative for healthier patients.

19 Mar 2019

TAVR procedure safe in patients with unusual valve anatomy

Compared with patients who had a typical tricuspid aortic valve, patients with a more unusual bicuspid aortic valve had a similar rate of death but a higher likelihood of stroke after undergoing a procedure to replace the valve by threading surgical equipment through an artery, according to research presented at the American College of Cardiology's 68th Annual Scientific Session.

18 Mar 2019

Study finds TAVR to be as good as open-heart surgery for patients at low surgical risk

A new trial comparing self-expanding transcatheter aortic valve replacement (TAVR) to standard open-heart surgery for valve replacement—this time in patients with severe aortic stenosis who are considered low surgical risk—found no difference in the combined rate of disabling stroke or death from any cause at two years.

18 Mar 2019

Researcher explore why some patients recover quickly after surgery while others don't

Why do some patients recover quickly after surgery, while others don't? That is an important question when treating older frail patients suffering from aortic stenosis. Lead author Dae Hyun Kim, M.D., M.P.H., Sc.D., and principle investigator Director Lewis A. Lipsitz in the Marcus Institute for Aging Research at Hebrew SeniorLife explore this question in a paper published today in the Journal of the American Medical Association Internal Medicine.

5 Feb 2019

Gerontologists assess change in patients' functional status after valve replacement procedure

Affecting an estimated one in eight people older than 75, aortic valve stenosis - a narrowing of the heart's main artery - makes the heart work harder to supply the body with blood, potentially limiting patient's activity levels an quality of life. Ultimately, aortic stenosis can lead to stroke, arrhythmia, heart failure and death.

5 Feb 2019

Novel 3D printing workflow helps predict leaky heart valves

More than one in eight people aged 75 and older in the United States develop moderate-to-severe blockage of the aortic valve in their hearts, usually caused by calcified deposits that build up on the valve's leaflets and prevent them from fully opening and closing.

11 Dec 2018

Most patients who underwent transcatheter valve replacement experience prosthesis-patient mismatch

In the largest multi-institutional study to date, led by researchers from Penn Medicine, the team found that among patients who underwent a transcatheter aortic valve replacement, a high number experienced severe and moderate cases of prosthesis-patient mismatch--meaning the implanted heart valve is too small for the patient which can lead to inadequate blood flow.

24 Sep 2018

Researchers discuss clinical application of bivalirudin in interventional cardiovascular procedures

Anticoagulation is imperative to reduce the incidence of thrombotic complications in patients undergoing percutaneous interventional cardiovascular procedures; however, this is at the expense of increased risk of bleeding.

11 Sep 2018

Patients who develop AFib following TAVR have greater risk for complications

Patients developing AFib after TAVR are at higher risk of death, stroke and heart attack compared to patients who already had AFib prior to the procedure, according to a study today in JACC: Cardiovascular Interventions. The paper is the first nationwide examination of patients who developed AFib for the first time following TAVR.

3 Sep 2018

Clinical trial provides 'strong signal' that TAVR is safe for patients with low surgical risk

Results of a clinical trial using transcatheter aortic valve replacement provided a "strong signal" that it is safe for patients with low surgical risk, potentially helping to open the way for broader use of the minimally invasive procedure, also known as TAVR.

30 Aug 2018

Hospitals battle for control over fast-growing heart-valve procedure

When Medicare in 2011 agreed to pay for a revolutionary procedure to replace leaky heart valves by snaking a synthetic replacement up through blood vessels, the goal was to offer relief to the tens of thousands of patients too frail to endure open-heart surgery, the gold standard.

17 Aug 2018

Mono-antiplatelet therapy after aortic heart valve replacements may work as well as two drugs

Current treatment guidelines say patients who undergo minimally invasive aortic heart valve replacements should receive two antiplatelet drugs to reduce the risk of dangerous blood clots.

14 Aug 2018

Women having heart attacks experience longer wait time for cardiac intervention

A recent study shows women having heart attacks experience higher than 30% longer wait time from the onset of symptoms to hospital arrival than men and a higher than 20% longer time from hospital arrival to cardiac intervention compared to men.

1 Aug 2018

Cardiac specialists review benefits of 'prehabilitation' before heart surgery for older, frail patients

High risk, frail heart patients might derive benefits from "prehabilitation," a strategy designed to enhance the recovery process after heart surgery by maintaining or improving the patient's overall physical and mental status before surgery, according to a group of eminent cardiac specialists writing in the Canadian Journal of Cardiology.

27 Jun 2018

Study shows effectiveness of novel risk tool to predict readmission rates after TAVR

A new study looked at the effectiveness of novel risk tool to predict 30-day readmission rates in patients undergoing transcatheter aortic valve replacement.

27 Apr 2018

Study examines efficacy of 3D printing, computer modeling to predict paravalvular leak in TAVR

A new study examines the effectiveness of 3D printing technology and computer modeling to predict paravalvular leak in patients undergoing transcatheter aortic valve replacement (TAVR). A common risk of TAVR is an ill-fitting valve which can lead to PVL.

27 Apr 2018

Researchers identify independent predictors of both delayed and early discharge post TAVR

A new study finds patients who stay in the hospital for more than 72 hours when undergoing trans-femoral transcatheter aortic valve replacement (TF-TAVR) procedure may be associated with negative short and long-term outcomes.

27 Apr 2018

Transcatheter Aortic Valve Replacement News and Research

High-risk surgical patients with severe aortic stenosis can benefit from new TAVR system

Researchers explore remodeling of cardiac tissues post-aortic valve replacement

Catheter-based valve replacement procedure safe for patients with common heart defect

Less invasive valve replacement can be safe and effective alternative for healthier patients

TAVR procedure safe in patients with unusual valve anatomy

Study finds TAVR to be as good as open-heart surgery for patients at low surgical risk

Researcher explore why some patients recover quickly after surgery while others don't

Gerontologists assess change in patients' functional status after valve replacement procedure

Novel 3D printing workflow helps predict leaky heart valves

Most patients who underwent transcatheter valve replacement experience prosthesis-patient mismatch

Researchers discuss clinical application of bivalirudin in interventional cardiovascular procedures

Patients who develop AFib following TAVR have greater risk for complications

Clinical trial provides 'strong signal' that TAVR is safe for patients with low surgical risk

Hospitals battle for control over fast-growing heart-valve procedure

Mono-antiplatelet therapy after aortic heart valve replacements may work as well as two drugs

Women having heart attacks experience longer wait time for cardiac intervention

Cardiac specialists review benefits of 'prehabilitation' before heart surgery for older, frail patients

Study shows effectiveness of novel risk tool to predict readmission rates after TAVR

Study examines efficacy of 3D printing, computer modeling to predict paravalvular leak in TAVR

Researchers identify independent predictors of both delayed and early discharge post TAVR

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