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Missing link between fructose, insulin resistance found

A new study in mice sheds light on the insulin resistance that can come from diets loaded with high-fructose corn syrup, a sweetener found in most sodas and many other processed foods.

2 Apr 2009

Drugs that act on 'fasting signal' may curb insulin resistance in obese

A report in the March issue of Cell Metabolism , a Cell Press publication, has found that a signal known to play a role during fasting also switches on early in the fat tissue of obese mice as they progress toward type 2 diabetes.

2 Apr 2009

Epigenetic mark guides stem cells toward their destiny

Not all stem cells are completely blank slates. Some, known as adult stem cells, have already partially embraced their fates, and are capable of becoming only cells of a particular type of tissue.

20 Mar 2009

Epigenetic mark guides stem cells toward their destiny

Not all stem cells are completely blank slates. Some, known as adult stem cells, have already partially embraced their fates and are capable of becoming only cells of a particular type of tissue. So how do these tissue-specific stem cells restrict their fate?

19 Mar 2009

Discovery of new pathway that regulates inflammation

Inflammation, the body's earliest response to damage or infection, can aid the healing process and trigger an immune response against invading pathogens.

11 Mar 2009

SOX9 protein may be a potential target for melanoma treatment

In a new study released today, researchers have shown that a specific protein plays an important role in inhibiting the development and spread of melanoma tumors in mouse and in human skin models.

11 Mar 2009

Important step toward in understanding the biology of stem cells

Researchers have found the factor that makes the difference between a stem cell in the intestine and any other cell.

5 Mar 2009

Missing link between fructose, insulin resistance found

A new study in mice sheds light on the insulin resistance that can come from diets loaded with high-fructose corn syrup, a sweetener found in most sodas and many other processed foods.

3 Mar 2009

Drugs that act on 'fasting signal' may curb insulin resistance in obese

3 Mar 2009

Protein complex shown to play pivotal role in stem cell development

Scientists at the Stanford University School of Medicine have identified a protein complex important in controlling whether embryonic stem cells retain their ability to become any cell in the body - a quality called pluripotency - or instead embark on a pathway of maturation and specialization.

2 Mar 2009

Why do teeth form in a single row?

A system of opposing genetic forces determines why mammals develop a single row of teeth, while sharks sport several, according to a study published in the journal Science.

26 Feb 2009

2 genes influence social behavior, visual-spatial performance in people with Williams syndrome

Unraveling the genetics of social behavior and cognitive abilities, researchers at the University of Utah and the Salk Institute for Biological Studies have traced the role of two genes,GTF2I and GTF2IRD, in a rare genetic disorder known as Williams Syndrome.

11 Feb 2009

Researchers identify mutation that causes inflammatory bowel disease

A team of scientists at The Scripps Research Institute has linked a mouse mutation to an increased susceptibility for developing inflammatory bowel disease -- represented in humans as Crohn's disease and ulcerative colitis, which together are estimated to affect more than a million people in the United States.

10 Feb 2009

Genetic interactions are the key to understanding complex traits

In recent years, genetic studies have uncovered hundreds of DNA variations linked to common diseases, such as cancer or diabetes, raising the prospect that scientists can gauge disease risk based on information in an individual's genome.

23 Jan 2009

Potential new biomarker for colon cancer

Cincinnati scientists have identified a new biomarker that could help predict a person's risk of developing colon cancer and how aggressive it may become.

19 Jan 2009

Discovery of more efficient way to create induced Pluripotent Stem (iPS) cells

A Boston University School of Medicine-led research team has discovered a more efficient way to create induced Pluripotent Stem (iPS) cells, derived from mouse fibroblasts, by using a single virus vector instead of multiple viruses in the reprogramming process.

7 Jan 2009