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New $2.3 million NCI grant awarded to Georgia Cancer Center to improve survival of patients with AML

Acute myeloid leukemia (AML) is a cancer that affects blood cells in the bone marrow -; the spongy tissue inside certain bones, where new blood cells are made.

17 Apr 2023

New tool provides insight into the developmental history of certain immune cells

A new tool that can uncover the developmental history of certain immune cells is now freely available worldwide. The tool provides insights into the stages that immune cells go through in a healthy individual and how this can be impacted in disease.

13 Apr 2023

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

In this inspiring interview, we speak to Dr. Radoje Drmanac, co-founder of Complete Genomics, about the past, present, and future of genomics research.

From MGI 13 Apr 2023

Virginia Tech to study the regulation of genes responsible for cannabinoid biosynthesis

Industrial cultivation of hemp is seeing a massive expansion in the United States due to new federal laws and consumer demand.

6 Apr 2023

AI outperforms the leading tools in predicting enzyme function

A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood.

30 Mar 2023

Study paves the way for wider applications of cell reprogramming in medicine

Sanford Burnham Prebys researchers have identified a group of proteins that could be the secret to cellular reprogramming, an emerging approach in regenerative medicine in which scientists transform cells to repair damaged or injured body tissues.

29 Mar 2023

COVID-19 activates endogenous retroviruses within our genome

Researchers assess the impact of SARS-CoV-2 infection on endogenous retroviruses of the LTR69 subfamily.

28 Mar 2023

Two distinct subtypes of insulin-producing beta cells identified

A team led by Van Andel Institute and Max Planck Institute of Immunobiology and Epigenetics scientists has identified two distinct subtypes of insulin-producing beta cells, or ß cells, each with crucial characteristics that may be leveraged to better understand and treat Type 1 and Type 2 diabetes.

28 Mar 2023

Notorious oncogene plays a direct role in disguising growing cancers from the immune system

Cancer-associated genes called oncogenes are well known to stimulate cell growth and division — causing tumors to balloon and spread.

28 Mar 2023

How does diet affect inflammation?

In a recent study published in the journal Nutrients, researchers in Italy suggest there is evidence that dietary factors may directly affect the immune system and play a role in chronic systemic inflammation.

26 Mar 2023

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. In a study published in the journal Immunity, researchers describe a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans.

22 Mar 2023

Investigating how gut microbiota affect neuroplasticity and neurodevelopment

In a recent study published in the journal Neuropharmacology, researchers in Pisa, Italy, explored how gut microbiota can influence neuroplasticity.

20 Mar 2023

Hox genes control stem cells involved in forming and repairing bone

Genes long known to control the formation of bones before birth also control bone healing later in life, a new study found.

20 Mar 2023

Research reveals the modulatory effect of anti-inflammatory metabolite on immune cells

Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate on T helper and T regulatory cells, which may lead to new therapeutic approaches to treating some autoimmune diseases.

15 Mar 2023

Important backup mechanism of human immune cells elucidated

The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses.

10 Mar 2023

First fully human ovarian organoids provide insights about female reproductive health and disease

Despite the fact that we all start out as an egg cell in one of our mother's ovaries, these human reproductive organs are surprisingly under-studied.

21 Feb 2023

Pluripotent stem cells can be a limitless source of transplantable HSPCs

Cells in the blood such as immune cells, red blood cells and other vital cell types are constantly renewed from stem cells, the so-called hematopoietic stem and progenitor cells (HSPCs).

19 Feb 2023

Brain cells may age faster in people with cocaine use disorder

A new study finds evidence from the DNA methylome that the biological age – different from the chronological age – of cells in Brodmann Area 9 of the prefrontal cortex might be greater in people with cocaine use disorder.

16 Feb 2023

Cocaine use disorder leads to changes in the 'methylome' of a brain region

Scientists tend to view substance addiction as primarily a disease of the brain. When we enjoy sex, food, music, or hobbies, regions of our brain within the reward pathway are flooded with pleasure-inducing dopamine.

14 Feb 2023

β-damascone can function as an efficient modulator of dendritic cell-mediated functions

Dendritic cells (DCs) are important players of the immune system with important functions such as the identification of infectious pathogens, production of cytokines (chemical signalers of the immune system), presentation of antigens to activate T-cells, and more.

10 Feb 2023

Transcription Factors News and Research

New $2.3 million NCI grant awarded to Georgia Cancer Center to improve survival of patients with AML

New tool provides insight into the developmental history of certain immune cells

From Sanger Sequencing to the Human Genome Project: The Evolution of DNA Sequencing Technology

Virginia Tech to study the regulation of genes responsible for cannabinoid biosynthesis

AI outperforms the leading tools in predicting enzyme function

Study paves the way for wider applications of cell reprogramming in medicine

COVID-19 activates endogenous retroviruses within our genome

Two distinct subtypes of insulin-producing beta cells identified

Notorious oncogene plays a direct role in disguising growing cancers from the immune system

How does diet affect inflammation?

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Investigating how gut microbiota affect neuroplasticity and neurodevelopment

Hox genes control stem cells involved in forming and repairing bone

Research reveals the modulatory effect of anti-inflammatory metabolite on immune cells

Important backup mechanism of human immune cells elucidated

First fully human ovarian organoids provide insights about female reproductive health and disease

Pluripotent stem cells can be a limitless source of transplantable HSPCs

Brain cells may age faster in people with cocaine use disorder

Cocaine use disorder leads to changes in the 'methylome' of a brain region

β-damascone can function as an efficient modulator of dendritic cell-mediated functions

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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