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Study characterizes mutations in neuraminidase of human-like H5N1 influenza viruses

A study published in PLOS PATHOGENS describes the prevalence and functions of mutations in neuraminidase enzyme of avian H5N1 influenza viruses that are preferentially selected in human H5N1 influenza viruses.

7 Feb 2023

Highly effective detection of cancer biomarkers using CRISPR

Most cancer diagnostic techniques rely on uncomfortable and invasive procedures, such as biopsies, endoscopies or mammograms.

1 Feb 2023

The main source of editing of the mpox virus genome during the 2022 outbreak

Researchers investigated the main source of editing of the 2022 mpox virus genome.

11 Jan 2023

Sustainable Laboratory Product of the Year - CellDrop Automated Cell Counter

The DeNovix CellDrop™ Automated Cell Counter has been awarded Sustainable Laboratory Product of the Year in the SelectScience® Scientists’ Choice Awards®.

From DeNovix Inc. 11 Jan 2023

Does the immunization order of vaccine types influence the efficacy of heterologous prime-boost vaccination, especially mRNA and protein-based vaccines?

A new study aimed to analyze whether the order of immunization of vaccine types impacted the efficacy of a heterologous prime-boost vaccination strategy.

6 Jan 2023

What is the role of SARS-CoV-2 non-structural protein 2 in repressing host antiviral immunity?

Researchers uncovered a novel mechanism that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other coronaviruses (CoVs) use to exploit host antiviral immune system to facilitate their replication.

5 Jan 2023

Sphere Fluidics appoints Richard Hammond as Chief Technical Officer

Sphere Fluidics, a company developing single cell analysis systems underpinned by its patented picodroplet technology, announced today that it has appointed Richard Hammond as Chief Technical Officer.

From Sphere Fluidics 16 Dec 2022

Research reveals the assembly dynamics of nucleocapsid protein condensates can be regulated by small molecules with therapeutic potential

Researchers developed a screening platform and identified molecules with anti-CoV activity.

12 Dec 2022

Understanding why respiratory infections are more common in the winter

Researchers investigate the role of extracellular vesicles in the innate nasal mucosal response to several respiratory viruses.

6 Dec 2022

Researchers uncover the host protease CAPN2 as a novel host factor that aids the infection of SARS-CoV-2

Researchers investigated the potential of the CAPN2 molecule as a therapeutic target against SARS-CoV-2.

5 Dec 2022

Feline coronavirus-infected domesticated cats found to possess cross-reactive anti-SARS-CoV-2 antibodies

In a recent study, researchers confirmed that feline coronavirus infection induced the production of cross-reactive antibodies against the SARS-CoV-2 receptor-binding domain in domestic cats.

28 Nov 2022

The biological properties of the SARS-CoV-2 E protein in the context of HIV-1

Researchers assessed the effectiveness of SARS-CoV and SARS-CoV-2 envelope proteins against HIV-1.

22 Nov 2022

β-cyclodextrin family found to be promising and cost-effective antiviral agents against SARS-CoV-2

Researchers identified β-cyclodextrins (β-CDs) as a safe and cost-effective drug against SARS-CoV-2 with a broad spectrum of activity.

18 Nov 2022

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Researchers presented a functional analysis of the SARS-CoV-2 open reading frame 3c (ORF3c) protein.

17 Nov 2022

SARS-CoV-2 ‘Deltacron’ variant exhibits immune-escape properties similar to Omicron BA.1

The SARS-CoV-2 Deltacron does not exhibit higher transmissibility or immune evasion than the Omicron BA.1 variant.

16 Nov 2022

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

Researchers reviewed technology advancements that will unlock the promise of biologically targeted messenger ribonucleic acid (mRNA) therapeutics beyond vaccines.

7 Nov 2022

Nebulized mRNA-encoded antibodies found to protect hamsters against COVID-19

New research describes a novel route of prevention, using messenger ribonucleic acid (mRNA) molecules that encode protective antibodies within the recipient.

2 Nov 2022

What is the impact of SARS-CoV-2 on HIV-1 infectivity?

In a new study, researchers assessed the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-CoV envelope (E) proteins on human immunodeficiency virus type 1 (HIV-1) infectivity.

31 Oct 2022

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

Researchers at Boston University made a chimeric recombinant SARS-CoV-2 encoding the spike glycoprotein gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate.

22 Oct 2022

New platform for gene editing may change the landscape of CRISPR-based therapeutics

A team of researchers at Northwestern University has devised a new platform for gene editing that could inform the future application of a near-limitless library of CRISPR-based therapeutics.

7 Oct 2022