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Subtle changes in mitochondrial DNA can have profound consequences for patient's health

Subtle changes in the DNA of mitochondria, the tiny power plants within cells, can have profound consequences for a patient's health.

16 Oct 2019

Scientists create bacteria with man-made DNA

In a landmark research study, a living organism (E. coli) has been made using entirely human-made DNA.

21 May 2019

Unique gene therapy approach paves new way to tackle rare, inherited diseases

Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function normally, and nonsense mutations cause 10-15 percent of all inherited genetic diseases, including Duchenne muscular dystrophy, spinal muscular atrophy, cystic fibrosis and polycystic kidney disease.

19 Feb 2019

RNA sequencing offers novel insights into the microbiome

Researchers have come up with a revolutionary strategy for studying the activity of the gut microbiome – using high-throughput sequencing of tRNA.

17 Dec 2018

Next-generation RNA sequencing technology sheds new light on human mitochondrial diseases

The ability to translate the genetic code into proteins is an essential step in all living organisms. A cornerstone of this molecular process is the ability of transfer RNA (tRNA) molecules to couple recognition of the genetic code with the cognate amino acid, which are the building blocks of proteins.

19 Oct 2018

Researchers describe cell mechanism that optimizes proteins production in stressful situations

The different genes within the genome must be expressed in precise levels and in the exact moment if the complex balance regulating cell activity is to be maintained.

19 Sep 2018

Scientists decipher workings of little-understood bacterial riboswitch

In a discovery that points to potential new antibiotic medicines, scientists from Rice University and the University of Michigan have deciphered the workings of a common but little-understood bacterial switch that cuts off protein production before it begins.

22 May 2018

UBC researchers unveil representative of most abundant giant viruses in the sea

Bodo saltans virus, the first isolated representative of the most abundant giant viruses in the sea, has been unveiled by researchers at the University of British Columbia.

29 Mar 2018

Researchers find link between genetic molecules in mosquitos and dengue fever

Researchers at the University of Missouri have found a link between genetic molecules in mosquitos and dengue fever.

25 Jan 2018

Mitochondrial error-correction mechanism essential for energy production of cells

Mitochondria generate most of the energy cells need through a respiratory chain for which they must produce their own proteins.

13 Dec 2017

New enzyme may one day enable genome surgery that erases harmful mutations

DNA editing just got a sharp, new pencil. Researchers have built an enzyme that can perform a previously impossible DNA swap, directly changing the DNA base pair from an A•T to a G•C.

26 Oct 2017

Researchers enhance safety, effectiveness of potential HIV vaccine using on/off genetic switch

By engineering an on/off switch into a weakened form of HIV, University of Nebraska-Lincoln researchers have enhanced the safety and effectiveness of a potential vaccine for the virus that has killed approximately 35 million people during the past 35 years.

30 Mar 2017

How does the brain control appetite?

Energy balance between energy intake and expenditure in our bodies is important for maintaining energy homeostasis to keep our bodies functioning properly. The appetite determines how much we eat, the energy intake, by communication between the brain and body.

4 Jan 2017

New study may shed light on diseases associated with mutations in aminoacyl tRNA synthetases

New research led by scientists at The Scripps Research Institute reveals that a human enzyme has changed little from its days as a bacterial enzyme. In fact, the enzyme appears to be unique in its ability to change its shape—and its job in cells—without overhauling its basic architecture.

14 Dec 2016

Researchers develop new method to map presence of short RNA-sequences in individual cell

Researchers at Karolinska Institutet have measured the absolute numbers of short, non-coding, RNA sequences in individual embryonic stem cells. The new method could improve the understanding of how our genes are regulated and different cell types develop.

1 Nov 2016

Researchers receive grant to investigate how gut microbiome influences breast cancer

Researchers from the University of Illinois at Chicago and the University of Chicago have received a three-year, $900,000 Defense Department grant to investigate how the gut microbiome – the trillions of bacteria, viruses and other bugs that make our digestive systems their home – influences breast cancer.

26 Oct 2016

Transfer RNA News and Research

Subtle changes in mitochondrial DNA can have profound consequences for patient's health

Scientists create bacteria with man-made DNA

Unique gene therapy approach paves new way to tackle rare, inherited diseases

RNA sequencing offers novel insights into the microbiome

Next-generation RNA sequencing technology sheds new light on human mitochondrial diseases

Researchers describe cell mechanism that optimizes proteins production in stressful situations

Scientists decipher workings of little-understood bacterial riboswitch

UBC researchers unveil representative of most abundant giant viruses in the sea

Researchers find link between genetic molecules in mosquitos and dengue fever

Mitochondrial error-correction mechanism essential for energy production of cells

New enzyme may one day enable genome surgery that erases harmful mutations

Researchers enhance safety, effectiveness of potential HIV vaccine using on/off genetic switch

How does the brain control appetite?

New study may shed light on diseases associated with mutations in aminoacyl tRNA synthetases

Researchers develop new method to map presence of short RNA-sequences in individual cell

Researchers receive grant to investigate how gut microbiome influences breast cancer

Scientists find how selenium gets integrated into protein molecules

MIT biologists unravel lncRNA structure-to-function relationships

TSRI scientists tackle decades-old challenge by re-creating primordial RNA world

Fluctuations in tRNA may play vital role in cancer metastasis

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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