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Dartmouth researchers use new strategies to target drug-resistant pathogens

By engineering antibacterial enzymes, Dartmouth investigators led by Karl Griswold, PhD are using novel strategies to target the prevalent drug-resistant bacterium Staphylococcus aureus.

3 Apr 2015

NCCC at Dartmouth designated again as Comprehensive Cancer Center by NCI

The National Cancer Institute has renewed its Cancer Center Support Grant to Norris Cotton Cancer Center at Dartmouth, continuing NCCC's designation as a Comprehensive Cancer Center.

29 Mar 2015

Experts unveil strategic roadmap to advance treatments for people with lymphoma

A committee of lymphoma experts today unveiled a strategic roadmap identifying key priority areas in both infrastructure and research that will be critical for advancing treatments for people with lymphoma.

27 Mar 2015

K2M announces enhanced complex spine portfolio with addition of its innovative NILE™ alternative fixation spinal system

NILE features low-profile, robust implants and intuitive and light ergonomic instruments, intended to provide stabilization between the spine and the rod, and to allow for reduction, translation, compression and distraction while sparing the anatomy...

26 Mar 2015

Scientists identify how mRNA deciphers critical information within genetic code

Case Western Reserve scientists have discovered that speed matters when it comes to how messenger RNA (mRNA) deciphers critical information within the genetic code — the complex chain of instructions critical to sustaining life. The investigators' findings, which appear in the March 12 journal Cell, give scientists critical new information in determining how best to engage cells to treat illness — and, ultimately, keep them from emerging in the first place.

18 Mar 2015

Guanabenz drug prevents myelin loss, alleviates symptoms of MS in animal models

An FDA-approved drug for high blood pressure, guanabenz, prevents myelin loss and alleviates clinical symptoms of multiple sclerosis (MS) in animal models, according to a new study.

13 Mar 2015

AMA and CDC join forces to Prevent Diabetes STAT

With more than 86 million Americans living with prediabetes and nearly 90 percent of them unaware of it, the American Medical Association and the Centers for Disease Control and Prevention today announced that they have joined forces to take urgent action to Prevent Diabetes STAT and are urging others to join in this critical effort.

12 Mar 2015

Survey: Physicians, patients overestimate risk of heart attack or death for possible ACS

Both physicians and patients overestimate the risk of heart attack or death for possible acute coronary syndrome (ACS) as well as the potential benefit of hospital admission for possible ACS.

12 Mar 2015

LSDF announces new Matching grants to promote treatments for devastating medical conditions

The Life Sciences Discovery Fund today announced nearly $1 million in Matching grants to two Washington-based companies to promote translation of promising treatments for devastating medical conditions from the laboratory to the commercial marketplace.

11 Mar 2015

Scientists find blood-based genomic biomarkers that could help identify young boys with ASD

In a study published in the current online issue of JAMA Psychiatry, an international team of scientists, led by researchers at the University of California, San Diego School of Medicine, report finding a highly accurate blood-based measure that could lead to development of a clinical test for autism spectrum disorder (ASD) risk in males as young as one to two years old.

10 Mar 2015

Phico Therapeutics gets £2.25M Translation Award to develop SASPject PT4 antibiotic for E. coli, K. pneumoniae

Phico Therapeutics, a biotechnology company developing a novel platform technology for a new generation of antibiotics aimed at overcoming antibacterial resistance, has been awarded a £2.25M Translation Award by the Wellcome Trust to develop its SASPject PT4 antibiotic, aimed at Escherichia coli and Klebsiella pneumoniae.

9 Mar 2015

Non-viral gene therapy provides relief for diabetics with constant foot pain

Walking barefoot on sand "felt like walking on glass" for Keith Wenckowski, who has lived with type-one diabetes for more than two decades.

6 Mar 2015

Halyard Health's net sales increase 2% to $439 million in fourth quarter 2014

Halyard Health, Inc. today reported year-end 2014 results and provided its 2015 outlook and related key planning assumptions.

4 Mar 2015

Brain scientists map changes in communication between nerve cells in rats

Lights, sound, action: we are constantly learning how to incorporate outside sensations into our reactions in specific situations. In a new study, brain scientists have mapped changes in communication between nerve cells as rats learned to make specific decisions in response to particular sounds. The team then used this map to accurately predict the rats' reactions. These results add to our understanding of how the brain processes sensations and forms memories to inform behavior.

3 Mar 2015

Scientists produce cartilage from embryonic stem cells

Scientists have succeeded in producing cartilage formed from embryonic stem cells that could in future be used to treat the painful joint condition osteoarthritis.

3 Mar 2015

Autism Speaks' affiliate DELSIA announces new funding for clinical trial of cognitive video game

Autism Speaks' not-for-profit affiliate Delivering Scientific Innovation for Autism has announced new funding for clinical testing of a cognitive video game designed to improve executive function skills in children and adolescents with autism.

3 Mar 2015

Novel financing technique may unlock funding for developing 'orphan' drugs to treat rare diseases

A paper published today, "Financing translation: Analysis of the NCATS rare-diseases portfolio" in Science Translational Medicine, demonstrates the potential of a new financing technique to reduce the risk associated with investing in the treatment of new diseases and potentially unlock new levels of funding for developing so-called "orphan" drugs.

28 Feb 2015

MD Anderson awarded more than $22 million in research grants from CPRIT

The University of Texas MD Anderson Cancer Center has received more than $22 million in research grants this week from the Cancer Prevention and Research Institute of Texas. Approximately half of the funds awarded for Individual Investigator Research Awards went to MD Anderson faculty as well as 40 percent of total IIRA awards that include those for children's and adolescent cancer and early detection and prevention.

21 Feb 2015

Targeted nanomedicines could help prevent heart attacks caused by atherosclerosis

Nanometer-sized "drones" that deliver a special type of healing molecule to fat deposits in arteries could become a new way to prevent heart attacks caused by atherosclerosis, according to a study in pre-clinical models by scientists at Brigham and Women's Hospital and Columbia University Medical Center.

19 Feb 2015

Sugar intake and tooth decay: an interview with Professor Nigel Pitts

Globally, dental caries (the technical term for tooth decay) is the most prevalent non-communicable disease, affecting 80% of the global population. Healthy teeth support overall well-being, while dental caries can contribute to high levels of pain and anxiety, as well as leading to other medical problems.

18 Feb 2015

Translation News and Research

Dartmouth researchers use new strategies to target drug-resistant pathogens

NCCC at Dartmouth designated again as Comprehensive Cancer Center by NCI

Experts unveil strategic roadmap to advance treatments for people with lymphoma

K2M announces enhanced complex spine portfolio with addition of its innovative NILE™ alternative fixation spinal system

Scientists identify how mRNA deciphers critical information within genetic code

Guanabenz drug prevents myelin loss, alleviates symptoms of MS in animal models

AMA and CDC join forces to Prevent Diabetes STAT

Survey: Physicians, patients overestimate risk of heart attack or death for possible ACS

LSDF announces new Matching grants to promote treatments for devastating medical conditions

Scientists find blood-based genomic biomarkers that could help identify young boys with ASD

Phico Therapeutics gets £2.25M Translation Award to develop SASPject PT4 antibiotic for E. coli, K. pneumoniae

Non-viral gene therapy provides relief for diabetics with constant foot pain

Halyard Health's net sales increase 2% to $439 million in fourth quarter 2014

Brain scientists map changes in communication between nerve cells in rats

Scientists produce cartilage from embryonic stem cells

Autism Speaks' affiliate DELSIA announces new funding for clinical trial of cognitive video game

Novel financing technique may unlock funding for developing 'orphan' drugs to treat rare diseases

MD Anderson awarded more than $22 million in research grants from CPRIT

Targeted nanomedicines could help prevent heart attacks caused by atherosclerosis

Sugar intake and tooth decay: an interview with Professor Nigel Pitts

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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