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Mayo Clinic researchers discover three new senolytic drugs

Mayo Clinic researchers have uncovered three new agents to add to the emerging repertoire of drugs that aim to delay the onset of aging by targeting senescent cells - cells that contribute to frailty and other age-related conditions.

9 Mar 2017

New technology provides extracorporeal support and enables recovery of damaged donor lungs

A multidisciplinary team led by Gordana Vunjak-Novakovic, Mikati Foundation Professor of Biomedical Engineering and Medical Sciences at Columbia Engineering, and Matt Bacchetta, associate professor of surgery at Columbia University Medical Center and NewYork-Presbyterian has--for the first time--maintained a fully functional lung outside the body for several days.

6 Mar 2017

Research survey shows positive attitude to adopt 3D culture technology among biomedical end users

Organ-on-chip and 3D cell culture technology have been highlighted as promising ways to ease the cost and inefficiency of the drug development process.

6 Mar 2017

Using Spherical Nucleic Acids to Track and Treat Disease

Spherical nucleic acids are structures that are made by taking a nanoparticle template and using chemistry to arrange short strands of DNA or RNA on the surface of those particles. The spherical core of the nanoparticle creates a spherical arrangement of DNA or RNA, similar to tiny little balls of nucleic acids.

From Pittcon 1 Mar 2017

Diagnosing Infections Through Molecules in Patient Breath

Over the past couple of decades, the analytical technology and the clinical microbiology insight needed to create a breath test for infections has seen a considerable number of advances and there are now numerous research teams focused on evaluating patient breath as a diagnostic fluid for infectious diseases. Significant challenges still need to be overcome.

From Pittcon 27 Feb 2017

New wearable brain-imaging device measures how brains sync up when humans interact

Great ideas so often get lost in translation -- from the math teacher who can't get through to his students, to a stand-up comedian who bombs during an open mic night.

27 Feb 2017

New compounds with potent anticancer activity could lessen side effects of oncological treatments

The Universitat Jaume I, the Spanish Centre for Advanced Scientific Research and the University of Pavia have patented new compounds with potent anticancer activity in breast and colon tumour cell lines that have low toxicity in healthy cells, which can dramatically decrease side effects during chemotherapy treatment.

23 Feb 2017

Mayo Clinic study finds link between biology of aging and idiopathic pulmonary fibrosis

A Mayo Clinic study has shown evidence linking the biology of aging with idiopathic pulmonary fibrosis, a disease that impairs lung function and causes shortness of breath, fatigue, declining quality of life, and, ultimately, death.

23 Feb 2017

UC San Diego researchers suggest transplanting good bacteria to treat patients with atopic dermatitis

Healthy human skin is alive with bacteria. In fact, there are more microorganisms living in and on the human body than there are human cells. Most can live on the human skin without harming the host, but in some people bacteria can negatively alter their health, maybe even become life-threatening.

23 Feb 2017

Crowdsourcing effort helps develop mathematical model to forecast scent of molecule

You can anticipate a color before you see it, based solely on the length of light waves. Music can be interpreted from notes on a page without being heard. Not so with odor. The only way to tell if something will smell like roses or turpentine, sea breeze or gasoline, is to sniff it.

21 Feb 2017

Research provides more evidence that mRNA vaccines can protect mice against Zika virus

Vaccine developers have successfully protected mice against Zika by injecting synthetic messenger RNA that encodes for virus proteins into the animals.

17 Feb 2017

UAB researchers show how GARP2 protein accelerates retinal degeneration in mice

In the retina of the eye, rod and cone cells turn light into electrical signals, the first step toward human vision.

16 Feb 2017

Analyzing copies of genes may offer new therapeutic approaches for ovarian cancer

A team of 18 University of California San Diego School of Medicine and Moores Cancer Center researchers has developed a new tool to analyze an often overlooked aspect of cancer genetics -- an alteration that results in the loss or gain in a copy of a gene.

15 Feb 2017

Plant-based drug for hemophilia shows promise in animal models

People with hemophilia require regular infusions of clotting factor to prevent them from experiencing uncontrolled bleeding. But a significant fraction develop antibodies against the clotting factor, essentially experiencing an allergic reaction to the very treatment that can prolong their lives.

13 Feb 2017

Next-generation sequencing assay shows accuracy, sensitivity in detecting genetic mutations in tumors

One of the most promising areas of cancer research is personalized therapy using precision medicine. The National Cancer Institute's NCI-MATCH is a large, ongoing clinical trial that matches tumors to therapies based on the tumor's genetic characteristics.

7 Feb 2017

Translation News and Research

Mayo Clinic researchers discover three new senolytic drugs

New technology provides extracorporeal support and enables recovery of damaged donor lungs

Research survey shows positive attitude to adopt 3D culture technology among biomedical end users

Using Spherical Nucleic Acids to Track and Treat Disease

Diagnosing Infections Through Molecules in Patient Breath

New wearable brain-imaging device measures how brains sync up when humans interact

New compounds with potent anticancer activity could lessen side effects of oncological treatments

Mayo Clinic study finds link between biology of aging and idiopathic pulmonary fibrosis

UC San Diego researchers suggest transplanting good bacteria to treat patients with atopic dermatitis

Crowdsourcing effort helps develop mathematical model to forecast scent of molecule

Research provides more evidence that mRNA vaccines can protect mice against Zika virus

UAB researchers show how GARP2 protein accelerates retinal degeneration in mice

Analyzing copies of genes may offer new therapeutic approaches for ovarian cancer

Plant-based drug for hemophilia shows promise in animal models

Next-generation sequencing assay shows accuracy, sensitivity in detecting genetic mutations in tumors

Mayo Clinic to test vaccine for providing lifelong immunity against precancerous breast lesions

Experts update cystic fibrosis guidelines for better diagnosis and personalized treatment

Cellectricon, Censo Biotechnologies launch joint technology access program to accelerate CNS and pain research

New study explores how protein production goes off script when skin cells turn cancerous

Tulane researchers discover cancer-causing role of protein thought to be tumor suppressor

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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