Transplant News and Research

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Steroids and weight loss products can accelerate hair loss, says hair loss expert

In a study due to be released next month, the world's leading hair transplant and hair loss expert Dr. Larry Shapiro will show that men and women have been losing their hair from using popular weight loss and work out products that contain whey protein isolate- and it's not just their genes that are to blame.

19 Feb 2010

Gen-Probe board authorizes $100M stock repurchase plan

Gen-Probe Incorporated announced today that its board of directors has authorized the repurchase of up to $100 million of the Company's common stock over the next year.

18 Feb 2010

Isotechnika Labs amends Isodiagnostika sales agreement with Paladin Labs

Isotechnika Pharma Inc. today announced that its wholly owned subsidiary, Isotechnika Labs, has amended its agreement with Paladin Labs Inc. concerning its remaining stake in the revenue stream from the Isodiagnostika business sold to Paladin on June 18, 2009. Under the agreement, Isotechnika Labs was entitled to receive a revenue stream equivalent to 88 percent of the net profits of Isodiagnostika through to June 18 2016.

18 Feb 2010

La Pitie hospital performs 200 implants of SynCardia temporary CardioWest Total Artificial Heart

SynCardia Systems, Inc., manufacturer of the SynCardia temporary CardioWest™ Total Artificial Heart, announced that Groupe hospitalier de la Pitié-Salpétrière (La Pitié) in Paris has performed 200 implants of the Total Artificial Heart, more than any other hospital in the world.

18 Feb 2010

CMC-NorthEast chooses Premier’s QualityAdvisor solution for improving patient care

The Premier healthcare alliance today announced that Carolinas Medical Center NorthEast (CMC-NorthEast) of Concord, N.C., selected Premier’s QualityAdvisor™ solution to improve delivery of patient care and safely reduce costly avoidable patient events.

18 Feb 2010

Genzyme announces fourth-quarter and full-year 2009 financial results

Genzyme Corp., a diversified, global biotechnology company, today announced fourth-quarter and full year 2009 financial results and provided 2010 guidance that reflects growth across its businesses and a focus on strengthening core areas of the company.

18 Feb 2010

SynCardia Total Artificial Heart recipient celebrates 10 years of life

On Feb. 22, Bill Wohl, a former recipient of the SynCardia temporary CardioWest™ Total Artificial Heart, will celebrate 10 years of enjoying life to the fullest with the donor heart he received at University Medical Center on Feb. 22, 2000.

17 Feb 2010

Belatacept costimulation blocker can prevent rejection of new organs by the immune system

Initial results of a study conducted at 100 centers worldwide indicate that belatacept, a first-in-class costimulation blocker can prevent the immune system rejecting new organs. The results also suggest that it may provide similar patient and graft survival to cyclosporine but with fewer side effects and superior kidney function after 12 months. The study, published today in the American Journal of Transplantation, provides the first findings to come from BENEFIT (Belatacept Evaluation of Nephroprotection and Efficacy as First-line Immunosuppression Trial).

17 Feb 2010

CalciMedica granted U.S. composition patent concerning key component of CRAC channel

CalciMedica today announced that the US Patent and Trademark Office has issued to CalciMedica US Patent No. 7,645,588, a composition patent involving STIM1, a key component of the calcium release-activated calcium (CRAC) channel. The patent, entitled "Composition comprising a cell comprising a STIM1 protein and an agent that modulates intracellular calcium and methods of use," has a priority date of March 4, 2003 and was issued on January 12, 2010.

17 Feb 2010

Special issue reviews current state of science in fetal therapy

Repairing birth defects in the womb. Inserting a tiny laser into the mother's uterus to seal off an abnormal blood flow and save fetal twins. Advancing the science that may allow doctors to deliver cells or DNA to treat sickle cell anemia and other genetic diseases before birth.

17 Feb 2010

Quark Pharmaceuticals' QPI-1002 receives orphan drug designation from FDA

Quark Pharmaceuticals, Inc., a world leader in the discovery and development of RNAi-based therapeutics, announced today that the US FDA has granted orphan drug designation for QPI-1002 (also referred to as "I5NP"), a synthetic siRNA targeting p53 mRNA for the prophylaxis of delayed graft function (DGF) in kidney transplant patients.

17 Feb 2010

Older patients waiting longer for kidneys from younger donors

One-third of people over the age of 65 wait longer than necessary for lifesaving, new kidneys because their doctors fail to put them in a queue for organs unsuitable to transplant in younger patients but well-suited to seniors, research from Johns Hopkins suggests.

16 Feb 2010

Children's Hospital of Philadelphia awarded two grants to research into cellular therapies for blood disorders

The new decade may herald an era of cell therapy -- treating human diseases by delivering highly specific beneficial cells. In the wake of an NIH decision late last year permitting federally funded researchers to use new lines of human embryonic stem cells, the door has opened more widely to stem cell research.

16 Feb 2010

Discharged VAD implanted pediatric patient receives successful heart transplant after eight months

The wait is over for 16-year-old Francesco "Frank" De Santiago. On January 29, De Santiago received a donor heart in a nine-hour transplant operation at Texas Children's Heart Center De Santiago made news last October as the first child ever discharged from a pediatric hospital with an implanted mechanical heart pump, or ventricular assist device (VAD). Until then, pediatric patients with VADs remained in the hospital, often in ICU, while awaiting a donor heart.

15 Feb 2010

Transition through hemogenic endothelial intermediate necessary for hematopoietic stem cell formation

Biologists at UC San Diego have identified the specific region in vertebrates where adult blood stem cells arise during embryonic development.

14 Feb 2010

Adult stem cell transplant therapy may help prevent amputations from PAD

Grant Medical Center recently completed the nation's first published study of a new procedure that may give hope to millions of patients facing lower limb amputations from peripheral arterial disease (PAD). PAD is a painful circulatory problem in the legs that affects 10 million Americans. If left untreated, it can lead to serious complications such as stroke, amputation and death.

12 Feb 2010

Mayo Clinic Health Letter features comprehensive coverage of the liver

The liver, the largest internal organ, is the body's ultimate multitasker. While the liver is not glamorous or sentimental -- there are no love songs about a broken liver -- it simultaneously plays a key role in the body's metabolic, digestive and regulatory systems.

12 Feb 2010

Study shows benefits of stent grafts over balloon angioplasty for patients who undergo dialysis

A randomized multicenter study of 190 patients at 13 medical centers shows-- for the first time-- the "superior" benefit of stent grafts over balloon angioplasty for maintaining function of dialysis access grafts in kidney failure patients who undergo dialysis. Until now, no other therapy has proven more effective than angioplasty.

12 Feb 2010

Genzyme announces 2-year data from eliglustat tartrate Phase 2 trial for Gaucher disease

Genzyme Corporation announced today two-year follow-up data from patients enrolled in the phase 2 clinical trial for its investigational oral therapy for Gaucher disease type 1 known as eliglustat tartrate (formerly Genz-112638). Continued improvements were observed across all endpoints, including bone disease, at the two-year timepoint, compared with baseline. The two-year results were presented for the first time today at the Lysosomal Disease Network WORLD Symposium in Miami, Fla.

12 Feb 2010

NMDP Phase III filgrastim trial: Biologics to provide pharmacy management services

Biologics, Inc., the leading cancer management company in the United States, announces that its Oncology Clinical Trial Services division has been selected by the National Marrow Donor Program® (NMDP), a nonprofit organization that facilitates unrelated hematopoietic cell transplants.

12 Feb 2010

Transplant News and Research

Steroids and weight loss products can accelerate hair loss, says hair loss expert

Gen-Probe board authorizes $100M stock repurchase plan

Isotechnika Labs amends Isodiagnostika sales agreement with Paladin Labs

La Pitie hospital performs 200 implants of SynCardia temporary CardioWest Total Artificial Heart

CMC-NorthEast chooses Premier’s QualityAdvisor solution for improving patient care

Genzyme announces fourth-quarter and full-year 2009 financial results

SynCardia Total Artificial Heart recipient celebrates 10 years of life

Belatacept costimulation blocker can prevent rejection of new organs by the immune system

CalciMedica granted U.S. composition patent concerning key component of CRAC channel

Special issue reviews current state of science in fetal therapy

Quark Pharmaceuticals' QPI-1002 receives orphan drug designation from FDA

Older patients waiting longer for kidneys from younger donors

Children's Hospital of Philadelphia awarded two grants to research into cellular therapies for blood disorders

Discharged VAD implanted pediatric patient receives successful heart transplant after eight months

Transition through hemogenic endothelial intermediate necessary for hematopoietic stem cell formation

Adult stem cell transplant therapy may help prevent amputations from PAD

Mayo Clinic Health Letter features comprehensive coverage of the liver

Study shows benefits of stent grafts over balloon angioplasty for patients who undergo dialysis

Genzyme announces 2-year data from eliglustat tartrate Phase 2 trial for Gaucher disease

NMDP Phase III filgrastim trial: Biologics to provide pharmacy management services

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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