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Quizartinib extends life and enhances wellbeing for AML patients with key mutation

In a study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, patients recently diagnosed with a common and aggressive form of acute myeloid leukemia reported having improved quality of life when a newly approved drug was part of the treatment plan.

11 Dec 2023

UB research identifies key mechanism in infantile cystinosis

University at Buffalo research has identified how a misstep in the genesis of a key component of the kidney causes infantile cystinosis, a rare disease that significantly shortens the lifespan of patients.

11 Dec 2023

New combinations and targeted therapies for acute myeloid leukemia on the horizon

The treatment landscape for acute myeloid leukemia (AML) is evolving rapidly, as research discoveries at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and other academic cancer centers advance new, more effective therapies for this aggressive blood cancer.

11 Dec 2023

CAR-T cell therapy remains viable for patients in lymphoma remission, study finds

A study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine suggests that CAR-T immunotherapy remains a viable option for patients who have lymphoma that goes into remission before the cell therapy begins.

11 Dec 2023

Study could pave the way for synergistic therapeutic combinations to better treat SF3B1-mutant MDS

A new study from researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations provides insight into the underlying mechanisms of gene mutations commonly seen in patients with myelodysplastic syndromes (MDS) and other myeloid neoplasms.

11 Dec 2023

MD Anderson and Rigel partner to expand olutasidenib evaluation in AML and other cancers

The University of Texas MD Anderson Cancer Center and Rigel Pharmaceuticals, Inc. today announced a multi-year strategic development collaboration to expand the evaluation of olutasidenib in acute myeloid leukemia (AML) and other hematologic cancers.

8 Dec 2023

Many patients may not benefit from gene-editing treatments for sickle cell disease

Federal approval of a breakthrough gene-editing technology that treats the pain and debilitating effects of sickle cell disease is cause for celebration among a community with few options for relief.

8 Dec 2023

Sympathetic nervous system and immune interplay: Key to metabolic regulation

A review in Advanced Science explores the interaction between the immune system and the sympathetic nervous system in regulating vital metabolic organs like the pancreas, liver, and adipose tissues. This comprehensive analysis provides insights into the neuroimmune relationships affecting metabolism, offering potential new therapeutic strategies for metabolic diseases.

5 Dec 2023

Transplantation of older organs may accelerate aging in younger people

Most organ transplantations involve supply from older donors to younger recipients. Aging cells can become senescent, a condition in which they stop multiplying and secrete chemicals that negatively affect neighboring cells.

5 Dec 2023

3D eye scans could help to track the progression of kidney disease

3D eye scans can reveal vital clues about kidney health that could help to track the progression of disease, research suggests.

5 Dec 2023

FDA clears Beckman Coulter Life Sciences AQUIOS STEM System for stem cell analysis

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, has received 510(k) clearance from the Food and Drug Administration (FDA) to distribute its popular AQUIOS STEM System in the United States.

From Beckman Coulter Life Sciences 4 Dec 2023

Routine thyroid hormone treatment for organ donors ineffective and potentially harmful

Doctors managing deceased organ donors routinely treat the donors' bodies with thyroid hormones in a bid to preserve heart function and increase the quantity and quality of hearts and other organs available for transplantation.

29 Nov 2023

Social support needed to reduce the barriers in accessing cardiac rehabilitation

Noted experts in cardiovascular rehabilitation attending the Third Jim Pattison-Mazankowski Alberta Heart Institute Cardiac Rehabilitation Symposium (Banff, April 21-23, 2023) observed that although cardiac rehabilitation benefits diverse groups of patients and affords the most cost-effective prevention for recurrent events, it is grossly underutilized globally.

28 Nov 2023

New stem cell-based treatment for Type 1 diabetes can reduce dependence on daily insulin injections

An innovative stem cell-based treatment for Type 1 diabetes can meaningfully regulate blood glucose levels and reduce dependence on daily insulin injections, according to new clinical trial results from the University of British Columbia (UBC) and Vancouver Coastal Health (VCH).

27 Nov 2023

Researchers take step toward developing cell therapy treatment for MS

An international team has shown that the injection of a type of stem cell into the brains of patients living with progressive multiple sclerosis (MS) is safe, well tolerated and has a long-lasting effect that appears to protect the brain from further damage.

27 Nov 2023

Abiomed announces enrollment of first patient in landmark RECOVER IV trial for AMI cardiogenic shock

Abiomed, part of Johnson & Johnson MedTech, announces the first patient in the world has been enrolled in the landmark RECOVER IV randomized controlled trial (RCT).

27 Nov 2023

Scientists succeed in mapping a central part of the immune system

A new paper in Science Advances details how scientists have succeeded in mapping a central part of the immune system - the HLA class II molecules - while accurately predicting how they display fragments of pathogens on the surface of cells.

24 Nov 2023

New approach to stem cell transplantation may overcome immune rejection

Cell and organ transplants can be lifesaving, but patients often encounter long waiting lists due to the shortage of suitable donors.

22 Nov 2023

From hospital to hospitality: Spin doctors brand getting sick as an adventure. It’s not.

The last time I stepped on a plane for vacation, for fun, was more than three years ago. I haven't been able to visit California, whose coast I adore. Nor Rome, where my husband and I lived for some time.

22 Nov 2023

Sex-specific brain immunometabolism differences may underlie increased Alzheimer's risk in women

Cleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer's and found that differences in brain immunometabolism – the interactions between the immune system and the ways cells create energy – may contribute to women's increased risk for the disease and its severity.

21 Nov 2023

Transplant News and Research

Quizartinib extends life and enhances wellbeing for AML patients with key mutation

UB research identifies key mechanism in infantile cystinosis

New combinations and targeted therapies for acute myeloid leukemia on the horizon

CAR-T cell therapy remains viable for patients in lymphoma remission, study finds

Study could pave the way for synergistic therapeutic combinations to better treat SF3B1-mutant MDS

MD Anderson and Rigel partner to expand olutasidenib evaluation in AML and other cancers

Many patients may not benefit from gene-editing treatments for sickle cell disease

Sympathetic nervous system and immune interplay: Key to metabolic regulation

Transplantation of older organs may accelerate aging in younger people

3D eye scans could help to track the progression of kidney disease

FDA clears Beckman Coulter Life Sciences AQUIOS STEM System for stem cell analysis

Routine thyroid hormone treatment for organ donors ineffective and potentially harmful

Social support needed to reduce the barriers in accessing cardiac rehabilitation

New stem cell-based treatment for Type 1 diabetes can reduce dependence on daily insulin injections

Researchers take step toward developing cell therapy treatment for MS

Abiomed announces enrollment of first patient in landmark RECOVER IV trial for AMI cardiogenic shock

Scientists succeed in mapping a central part of the immune system

New approach to stem cell transplantation may overcome immune rejection

From hospital to hospitality: Spin doctors brand getting sick as an adventure. It’s not.

Sex-specific brain immunometabolism differences may underlie increased Alzheimer's risk in women

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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