Troponin News and Research

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Researchers use simple tactics to reduce unnecessary blood tests, health care spending

Researchers at Johns Hopkins Bayview Medical Center used two relatively simple tactics to significantly reduce the number of unnecessary blood tests to assess symptoms of heart attack and chest pain and to achieve a large decrease in patient charges.

2 Jul 2014

Cardiac biomarkers aid microvascular risk prediction in diabetics

Assessing cardiac biomarkers results in a moderate improvement in the ability to predict microvascular complications in patients with Type 2 diabetes, say researchers.

6 Jun 2014

New blood test can detect heart attacks hours faster than current gold-standard blood test

A new blood test can detect heart attacks hours faster than the current gold-standard blood test, according to a study led by Loyola University Chicago Stritch School of Medicine researchers.

26 Feb 2014

Scientists create 3-D elastic membrane that is precisely shaped to match heart's epicardium

Igor Efimov, PhD, at the School of Engineering & Applied Science at Washington University in St. Louis and an international team of biomedical engineers and materials scientists have created a 3-D elastic membrane made of a soft, flexible, silicon material that is precisely shaped to match the heart's epicardium, or the outer layer of the wall of the heart.

26 Feb 2014

Study: 85% of patients who have heart attacks after surgery do not experience traditional symptoms

Without administering a simple blood test in the first few days after surgery, 85 percent of the heart attacks or injuries patients suffer could be missed, according to a study in the March issue of Anesthesiology.

19 Feb 2014

Morning blood pressure tied to target-organ damage

Physicians should ask patients to take home blood pressure readings in the morning as well as the evening before making therapeutic decisions, say researchers.

3 Feb 2014

CPCs not powerful enough to be used as a single tool in diagnosis of acute myocardial infarction

Using chest pain characteristics (CPCs) specific to women in the early diagnosis of acute myocardial infarction (AMI, heart attack) in the emergency department does not seem to be supported by the findings of a study published by JAMA Internal Medicine, a JAMA Network publication.

27 Nov 2013

New method for quickly ruling out serious acute coronary disease of chest pains

Researchers at Karolinska Institutet in Sweden have tested a new method for quickly ruling out acute myocardial infarction or other serious acute coronary disease in Emergency department patients complaining of chest pains.

5 Nov 2013

New study finds association between OSA and subclinical myocardial injury

Obstructive sleep apnea is known to be associated with an increased incidence of cardiovascular disease. Now a new study indicates that OSA is associated with subclinical myocardial injury, as indicated by increased high sensitivity troponin T levels. Elevated hs-TnT levels are predictive of both coronary heart disease and heart failure in the general population.

25 Oct 2013

Arrowhead initiates Phase 1 study of ARC-520 for treatment against chronic HBV infection

Arrowhead Research Corporation (NASDAQ: ARWR), a biopharmaceutical company developing targeted RNAi therapeutics, today announced that it completed enrollment in a Phase 1 clinical trial of ARC-520, its RNAi-based candidate against chronic hepatitis B virus infection.

9 Oct 2013

Final patient completion of phase II study of TR040303 in patients treated for acute myocardial infarction announced by Trophos

Trophos SA, a clinical stage pharmaceutical company developing innovative therapeutics from discovery to clinical validation for indications with under-served needs in neurology and cardiology, announces today the final patient completion of a phase II study of TR040303 in patients treated for acute myocardial infarction (MI). Outcome data of this study is expected to be available towards the end of 2013.

2 Oct 2013

Fingerstick blood sample test using i-STAT device not accurate in determining troponin level: Study

Researchers have determined that fingerstick cardiac troponin I assay testing using thepoint-of-care i-STAT device is not accurate enough to determine the exact troponin level without the application of a corrective term.

21 Sep 2013

Innovative platform improves diagnostics and detection of biomolecules

Separating target molecules in biological samples is a critical part of diagnosing and detecting diseases. Usually the target and probe molecules are mixed and then separated in batch processes that require multiple pipetting, tube washing and extraction steps that can affect accuracy.

18 Sep 2013

Women with acute coronary syndrome less likely to have chest pain than men

A higher proportion of women than men 55 years and younger did not have chest pain in acute coronary syndromes (ACS, such as heart attacks or unstable angina), although chest pain was the most common symptom for both sexes, according to a study published by JAMA Internal Medicine, a JAMA Network publication.

17 Sep 2013

Biomarker strategy in suspected ACS patients has potential to change clinical practice

An emergency department strategy that uses two biomarkers to triage patients with suspected acute coronary syndrome (ACS) can increase the rate of early, safe hospital discharge, according to results of the Biomarkers in Cardiology 8 (BIC-8) trial.

5 Sep 2013

High sensitive troponin test may help doctors improve diagnosis in patients with heart attack

Abbott (NYSE: ABT) announced today promising preliminary results from a study presented at the ESC Congress 2013, suggesting that its high sensitive troponin test may help doctors improve the diagnosis and prognosis of patients presenting with symptoms of a heart attack.

4 Sep 2013

Omecamtiv mecarbil fails to achieve primary endpoint in phase II ATOMIC-AHF study

Omecamtiv mecarbil, a cardiac myosin-activator, did not achieve its primary efficacy endpoint in reducing dyspnoea (shortness of breath) in patients with acute heart failure, according to the results of the phase II ATOMIC-AHF (Acute Treatment with Omecamtiv Mecarbil to Increase Contractility in Acute Heart Failure) study.

3 Sep 2013

Inflating blood pressure cuff ahead of heart bypass surgery reduces heart injury

Inflating a blood pressure cuff on the upper arm just ahead of heart bypass surgery reduces heart injury and might even improve bypass patients’ long-term survival, according to an Article published in The Lancet.

16 Aug 2013

Nitrous oxide does not increase heart attack risk, study finds

Nitrous oxide - best known as laughing gas - is one of the world's oldest and most widely used anesthetics. Despite its popularity, however, experts have questioned its impact on the risk of a heart attack during surgery or soon afterward. But those fears are unfounded, a new study indicates.

19 Jun 2013

Researchers report that two biomarkers appear to indicate risk for silent strokes

Two biomarkers widely being investigated as predictors of heart and vascular disease appear to indicate risk for "silent" strokes and other causes of mild brain damage that present no symptoms, report researchers from The Methodist Hospital and several other institutions in an upcoming issue of Stroke (now online).

5 Jun 2013