Tryptophan News and Research

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Tryptophan is one of the 20 standard amino acids, as well as an essential amino acid in the human diet.

Coronacept - A trap-and-destroy molecule against SARS-CoV-2

A new study published on the preprint server bioRxiv* in August 2020 reports a novel engineered molecule based on human and other mammalian orthologues of ACE2 fused with the Fc part of the antibody. This molecule interacts more tightly with the viral receptor-binding domain (RBD) to constitute a powerful immunoadhesin that targets the virus for destruction.

17 Aug 2020

New biomolecules can benefit agricultural and pharmaceutical sectors

These molecules of plant origin may be of use to the agricultural and pharmaceutical sectors. Researchers from the Biochemistry and Biotechnology Research Group at the Universitat Jaume Ihave identified and obtained biomolecules of plant origin, which have been tested against plant pathogens and pathogens of clinical interest, with the aim of obtaining high-quality commercial products that can be applied in the agricultural and pharmaceutical sectors.

23 Jul 2020

Experimental therapy slows zika replication and prevents microcephaly in mice

An international group of researchers have discovered that inhibiting AHR (aryl hydrocarbon receptor), a protein with roles in regulating immunity, stem cell maintenance and cellular differentiation, enables the immune system to combat replication of zika virus in the organism far more effectively.

20 Jul 2020

Study explores the role of gut Piezo1 in sensing of bacterial RNA

In a new study published in Cell, "RNA sensing by gut Piezo1 is essential for systemic serotonin synthesis", a research team led by Kenta Maruyama M.D., Ph.D. from National Institute for Physiological Sciences explored the role of Piezo1, a mechano-sensing receptor, in the sensing of bacterial RNA.

7 Jul 2020

Study: Oats and rye brans reduce weight gain, hepatic inflammation

In a newly published experimental study, the consumption of dietary fibre from oat and rye brans supported the growth of beneficial gut microbiota, which in turn ameliorated cholesterol metabolism, enhanced gut barrier function and reduced hepatic inflammation.

2 Jul 2020

Researchers show how upregulation of a single gene by SARs-CoV-2 can trigger cytokine storm

The SARS-CoV-19 virus initially has a limited capability to invade, attacking only one intracellular genetic target, the aryl hydrocarbon receptors (AhRs).

29 Jun 2020

Researchers explore amino acids for a new diet approach

A new diet approach that restricts essential amino acids was explored in new research by a team of international scientists from Australia, Denmark, and Germany.

11 Jun 2020

Study reveals essential components of dietary restriction

Studies by Monash Biomedicine Discovery Institute (BDI), have provided a new understanding into the roles two essential amino acids play in metabolic health, which may help scientists in the fight against obesity.

9 Jun 2020

Engineered botox more effective

A new study reports on an engineered botulinum neurotoxin (botox) that is more effective as well as safer to use in various medical procedures. The study was published in March 2020 in the open-access journal PLOS Biology.

17 Mar 2020

Chemical in veggies help heal fatty liver

A new study shows that a compound naturally occurring in a variety of commonly used vegetables as well as being produced by gut microbes is very useful in melting fat away from a fatty liver.

9 Feb 2020

Scientists identify new biomarker for identifying individuals at risk of depression

Chronic pain, or inflammation, is believed to be one of the major factors in the onset of major depressive disorder.

8 Feb 2020

Unveiling the structure of the influenza virus

The flu season is coming, and the frigid temperatures make it worse. The influenza B virus is the causative agent of the common flu, but over the past years, it has become more potent in causing disease. Now, a team of MIT scientists has found and unveiled the structure of the virus, particularly the key influenza protein, in the hopes to develop new drugs to combat influenza.

4 Feb 2020

New study provides better understanding of blood clot formation in cancer patients

Researchers have identified a potential new signaling pathway that may help further the understanding of blood clot formation in cancer patients and ultimately help prevent this complication from occurring.

22 Nov 2019

Increasing anti-tumor activity of compound extracted from an Amazon plant

Researchers in Brazil have prepared modified forms of the alkaloids produced by Uncaria guianensis, a woody vine native to the Amazon Rainforest.

31 Oct 2019

Metabolic imbalance in cancer patients associated with resistance to immune checkpoint blocker

A metabolic imbalance in some cancer patients following treatment with a checkpoint inhibitor drug, nivolumab, is associated with resistance to the immunotherapy agent and shorter survival, report scientists from Dana-Farber Cancer Institute, in collaborative work with the Broad Institute of MIT and Harvard.

25 Sep 2019

Researchers find synergistic connection between two deadly blood-clotting diseases

Two rare but potentially deadly blood-clotting diseases, namely thrombotic thrombocytopenic purpura, or TTP, and hemolytic uremic syndrome, or HUS, show similar pathologies -- a multitude of painful blockages in small blood vessels that cause varying degrees of organ injury throughout the body. However, the two disorders have distinct biological mechanisms.

8 Sep 2019

Researchers develop new nanotheranostic system that solves many problems

Theranostics is an emerging field of medicine whose name is a combination of "therapeutics" and "diagnostics".

9 Jul 2019

Dangerous brain parasite invades host cell, maintains steady nutrient supply

A team of researchers has found that a dangerous type of parasite that affects the brain, maintains a stable supply of essential nutrients as it replicates in the host cell. In an unexpected turn of events, the body itself delivers food to the harmful predator.

20 Jun 2019

Diabetes drug reduces anxiety-like behaviors in mice

The antidiabetic medication metformin reduces anxiety-like behaviors in male mice by increasing serotonin availability in the brain, according to a study published in JNeurosci.

From Society for Neuroscience 4 Jun 2019

Research identifies new target that may help develop new treatments for common STD

Research led by Ashok Aiyar, PhD, Associate Professor of Microbiology, Immunology and Parasitology at LSU Health New Orleans School of Medicine, has identified a target that may lead to the development of new treatments for the most common sexually transmitted infection in the US.

31 May 2019