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Next-generation sequencing and machine learning used to map genetic landscape of pancreatic cancer

A new research paper was published in Oncotarget's Volume 15 on February 5, 2024, entitled, "Genetic and therapeutic landscapes in cohort of pancreatic adenocarcinomas: next-generation sequencing and machine learning for full tumor exome analysis."

15 Feb 2024

Study explores health benefits of selenium and zinc-enriched eggs

Researchers investigated the effect of a diet of selenium- and/or zinc-enriched eggs (SZE) on oxidative stress, cognitive impairment, and intestinal flora in D-galactose-induced aging mice.

15 Feb 2024

Early detection may help Kentucky tamp down its lung cancer crisis

Anthony Stumbo's heart sank after the doctor shared his mother's chest X-ray.

15 Feb 2024

Combo of targeted and immunotherapy may boost NSCLC treatment by overcoming immune resistance and enhancing anti-tumor activity

Researchers evaluated rational combination treatment regimens for advanced/metastatic non-small-cell lung cancer (NSCLC).

15 Feb 2024

Study uncovers critical roles for USP1 in Ewing sarcoma

A new research paper was published in Genes & Cancer on February 5, 2024, entitled, "Roles of USP1 in Ewing sarcoma."

14 Feb 2024

Enhancing survival in advanced pancreatic cancer with ablative MR-guided radiation therapy

A study co-led by researchers at Miami Cancer Institute, part of Baptist Health South Florida, found that ablative stereotactic magnetic resonance (MR)-guided adaptive radiation therapy may improve local control (LC) and overall survival (OS) in patients with borderline resectable (BRPC) and locally advanced pancreas cancer (LAPC).

14 Feb 2024

Smoking, infection, and BMI found to significantly sway immune response, study shows

Study reveals how smoking, CMV latent infection, and BMI significantly influence cytokine release, impacting immune response variability and potentially affecting disease risk.

14 Feb 2024

Researchers develop enhanced immunotherapy for multiple myeloma treatment

Immunotherapy is already improving treatment options for many cancer types, but research groups keep exploring ways to boost the body's immune response against the tumor.

14 Feb 2024

Novel three-drug combo shows promise in advanced HER2-negative breast cancer treatment

A novel three-drug combination achieved notable responses in patients with advanced HER2-negative breast cancer, according to new research directed by investigators from the Johns Hopkins Kimmel Cancer Center.

14 Feb 2024

Phosphoproteomic profiling reveals the complex interplay of immune cells in tumors

Researchers from the Icahn School of Medicine at Mount Sinai, in collaboration with the Clinical Proteomic Tumor Analysis Consortium of the National Institutes of Health, The University of Texas MD Anderson Cancer Center, Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, and others, have unveiled a detailed understanding of immune responses in cancer, marking a significant development in the field.

14 Feb 2024

Research reveals new insights into the role of efferocytosis in pancreatic cancer liver metastasis

A research paper published today (14 February 2024) in Nature Cancer details new insights into the role of efferocytosis – the burying of dead cells – in pancreatic cancer that spreads to the liver.

14 Feb 2024

Advanced melanoma survival rates improve significantly from 2013 to 2019, Dutch study finds

The change in overall survival (OS) among advanced melanoma patients diagnosed between 2013 and 2021.

14 Feb 2024

Study finds interleukin-24 enhances CAR-T cell therapy's effectiveness against cancer stem cells

The effect of Interleukin-24 (IL-24) on CSCs and CAR-T cell therapy.

14 Feb 2024

New AI-powered protein mapping tool optimizes cancer therapy

Scientists have developed a new AI tool that maps the function of proteins in a cancerous tumour, enabling clinicians to decide how to target treatment in a more precise way.

13 Feb 2024

Magnesium's pivotal role in slowing aging's impact

Review highlights magnesium's critical role in mitigating aging hallmarks, including telomere attrition, genomic instability, epigenetic alterations, loss of proteostasis, mitochondrial dysfunction, cellular senescence, and stem cell exhaustion, suggesting that maintaining adequate magnesium levels could support healthy aging.

13 Feb 2024

Study demonstrates chemo-preventive properties of alpha-santalol against prostate cancer development

Extracted from the core of sandalwood trees (santalum album tree), sandalwood oil has been used for many centuries by several cultures throughout the world for perfume, soaps, incense and candles.

13 Feb 2024

Researchers develop groundbreaking technique to detect chemoresistance using ultrasound

Researchers at Purdue University have developed a technique to better predict chemotherapy resistance in canines and humans.

13 Feb 2024

Novel assay enhances pediatric cancer treatment by identifying clinically relevant gene fusions

Identification of specific gene fusions is critical for the successful targeted treatment of pediatric cancer patients.

13 Feb 2024

Combination therapy offers breakthrough in NSCLC treatment

A specific combination of targeted therapy and immunotherapy may better help patients with non-small cell lung cancer (NSCLC) overcome inherent immune resistance and reinvigorate anti-tumor activity, according to a new study led by a researcher from The University of Texas MD Anderson Cancer Center.

13 Feb 2024

Mad2 expression levels with chromosomal abnormalities can be a biomarker for esophageal cancer

A new research paper was published in Oncotarget's Volume 15 on February 5, 2024, entitled, "Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational modifications in its promoter region in human esophageal cancer samples."

12 Feb 2024

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Tumor News and Research

Next-generation sequencing and machine learning used to map genetic landscape of pancreatic cancer

Study explores health benefits of selenium and zinc-enriched eggs

Early detection may help Kentucky tamp down its lung cancer crisis

Combo of targeted and immunotherapy may boost NSCLC treatment by overcoming immune resistance and enhancing anti-tumor activity

Study uncovers critical roles for USP1 in Ewing sarcoma

Enhancing survival in advanced pancreatic cancer with ablative MR-guided radiation therapy

Smoking, infection, and BMI found to significantly sway immune response, study shows

Researchers develop enhanced immunotherapy for multiple myeloma treatment

Novel three-drug combo shows promise in advanced HER2-negative breast cancer treatment

Phosphoproteomic profiling reveals the complex interplay of immune cells in tumors

Research reveals new insights into the role of efferocytosis in pancreatic cancer liver metastasis

Advanced melanoma survival rates improve significantly from 2013 to 2019, Dutch study finds

Study finds interleukin-24 enhances CAR-T cell therapy's effectiveness against cancer stem cells

New AI-powered protein mapping tool optimizes cancer therapy

Magnesium's pivotal role in slowing aging's impact

Study demonstrates chemo-preventive properties of alpha-santalol against prostate cancer development

Researchers develop groundbreaking technique to detect chemoresistance using ultrasound

Novel assay enhances pediatric cancer treatment by identifying clinically relevant gene fusions

Combination therapy offers breakthrough in NSCLC treatment

Mad2 expression levels with chromosomal abnormalities can be a biomarker for esophageal cancer

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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