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Novel dual-target CAR T cell therapy shows promise in treating recurrent glioblastoma

Targeting two brain tumor-associated proteins-;rather than one-;with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), an aggressive form of brain cancer, according to early results from the first six patients treated in an ongoing Phase I clinical trial led by researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

13 Mar 2024

Exploring the power of diet: A new frontier in disease management and cancer treatment

The therapeutic potential of and molecular mechanisms through which dietary interventions impact a wide range of human diseases.

13 Mar 2024

New custom-designed proteins can efficiently reach intramembrane targets

Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, Scripps Research chemists have demonstrated new custom-designed proteins that can efficiently reach these "intramembrane" targets.

13 Mar 2024

Universal screening of congenital cytomegalovirus infection with pooled saliva tests

New study displays successful implementation of pooled saliva tests for universal screening of congenital cytomegalovirus (cCMV) infection.

12 Mar 2024

MIT researchers develop new method to quickly screen cancer-associated genetic mutations

Tumors can carry mutations in hundreds of different genes, and each of those genes may be mutated in different ways -; some mutations simply replace one DNA nucleotide with another, while others insert or delete larger sections of DNA.

12 Mar 2024

Increased stiffness in aging skin may contribute to higher rates of metastatic skin cancer

Age-related changes that cause the skin to stiffen and become less elastic may also contribute to higher rates of metastatic skin cancer in older people, according to research by investigators from the Johns Hopkins Kimmel Cancer Center.

12 Mar 2024

New “GPS nanoparticle” delivers a genetic punch to the protein implicated in tumor spread

A newly developed "GPS nanoparticle" injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers from Penn State.

11 Mar 2024

LAG-3 protein structure may be the key to unlocking new cancer treatments

A molecular “snapshot” of a protein can be critical to understanding its function. Scientists at Stanford and NYU have published and investigated a new structure of the protein LAG-3 which could enable the development of new cancer treatments.

11 Mar 2024

UH College of Pharmacy secures CPRIT funding to fight familial adenomatous polyposis

The University of Houston College of Pharmacy is included in a $68.5 million funding package from the Cancer Prevention and Research Institute of Texas (CPRIT).

11 Mar 2024

UCLA and UAMS teams secure $3.2 million NIH grant for melanoma research

A team of investigators from the UCLA Health Jonsson Comprehensive Cancer and the University of Arkansas for Medical Sciences (UAMS) Winthrop P. Rockefeller Cancer Institute was awarded a $3.2 million grant from the National Institutes of Health to identify new ways to prevent and overcome treatment resistance to targeted therapy in patients with all sub-types of cutaneous melanoma, an aggressive form of skin cancer.

11 Mar 2024

Choosing the right fat for keto diets: Fish oil's significant role in cancer prevention

The anti-cancer efficacy of different oils consumed as a part of ketogenic diets (KDs).

11 Mar 2024

Key protein identified in protecting women from fatty liver disease

New research from Karolinska Institutet in Sweden shows how oestrogen protects against MASLD, a fatty liver disease that has increased dramatically during the current obesity epidemic.

9 Mar 2024

New PET radiotracer distinguishes diseased tissues based on fructose metabolism

A new PET radiotracer can differentiate diseased tissues from healthy tissues based on fructose metabolism, according to new research published in the March issue of The Journal of Nuclear Medicine.

8 Mar 2024

Study evaluates diet, exercise patterns among colorectal cancer patients with overweight/obesity

Obesity is a chronic metabolic disease associated with the development of several other diseases, including cancer. The present study aims to evaluate the eating habits, physical activity, and clinical profiles of colorectal cancer (CRC) patients with overweight/obesity.

7 Mar 2024

Study uncovers unexpected level of complexity hidden within neutrophils

In a study published in Cell on March 5, Prof. Zhang Xiaoming at the Shanghai Institute of Immunity and Infection (SIII) of the Chinese Academy of Sciences and Profs. Gao Qiang, Fan Jia and Yang Li at Fudan University have uncovered an unexpected level of complexity hidden within neutrophils, which were previously thought to be a relatively uniform population of short-lived immune cells.

6 Mar 2024

Gut bacteria strains could be the key to predicting cancer treatment success

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Tumor News and Research

Novel dual-target CAR T cell therapy shows promise in treating recurrent glioblastoma

Exploring the power of diet: A new frontier in disease management and cancer treatment

New custom-designed proteins can efficiently reach intramembrane targets

Universal screening of congenital cytomegalovirus infection with pooled saliva tests

MIT researchers develop new method to quickly screen cancer-associated genetic mutations

Increased stiffness in aging skin may contribute to higher rates of metastatic skin cancer

New “GPS nanoparticle” delivers a genetic punch to the protein implicated in tumor spread

LAG-3 protein structure may be the key to unlocking new cancer treatments

UH College of Pharmacy secures CPRIT funding to fight familial adenomatous polyposis

UCLA and UAMS teams secure $3.2 million NIH grant for melanoma research

Choosing the right fat for keto diets: Fish oil's significant role in cancer prevention

Key protein identified in protecting women from fatty liver disease

New PET radiotracer distinguishes diseased tissues based on fructose metabolism

Study evaluates diet, exercise patterns among colorectal cancer patients with overweight/obesity

Study uncovers unexpected level of complexity hidden within neutrophils

Gut bacteria strains could be the key to predicting cancer treatment success

Researchers develop new algorithm to identify high-risk precancerous lesions on the fallopian tubes

Scientists develop robust iPSC-derived rejuvenated T lymphocytes for cervical cancer treatment

Comparing CEUS imaging features in patients with hepatic lymphoepithelioma-like carcinoma and HCC

Scientists design breakthrough drug to combat deadly pancreatic cancer mutation

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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