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The association between diet and colorectal cancer risk

The genetic variants that modify the association between diet and colorectal cancer (CRC) risk.

1 Mar 2024

COVID-19's lasting mark: Long-term smell and taste loss

Study reveals prolonged olfactory and gustatory dysfunction in some COVID-19 recoverees, highlighting a need for better clinical support and understanding of long-term effects.

29 Feb 2024

UCLA researchers uncover dual role of GAN gene in neurological disorder, head and neck cancer

Researchers from the UCLA Health Jonsson Comprehensive Cancer Center show for the first time that a gene usually linked to giant axonal neuropathy, a rare and severe neurological condition, also plays a role in inhibiting aggressive tumor cell growth in head and neck cancers.

29 Feb 2024

New tool unravels the mystery of DNA-RNA interactions in single cells

Cancers begin with abnormal changes in individual cells, and the ability to track the accumulation of mutations at the single-cell level can shed new light on the early stages of the disease. Such knowledge could enable more effective early detection and treatment options for patients as well as more accurate predictions of disease progression.

29 Feb 2024

New approach detects T cells in "cold" tumors, paves way for broader immunotherapy

Most cancers are thought to evade the immune system. These cancers don't carry very many mutations, and they aren't infiltrated by cancer-fighting immune cells. Scientists call these cancers immunologically "cold."

29 Feb 2024

Developing a prognostic model for bladder urothelial cancer using oxidative stress signatures

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 3, entitled, "Prognostic model development and molecular subtypes identification in bladder urothelial cancer by oxidative stress signatures."

28 Feb 2024

Uncovering the role of mucus in pancreatic cancer transformation

Knowing exactly what's inside a tumor can maximize our ability to fight cancer. But that knowledge doesn't come easy. Tumors are clusters of constantly changing cancer cells.

28 Feb 2024

New lung cell atlas unveils pathways to lung adenocarcinoma development

Researchers at The University of Texas MD Anderson Cancer Center built a new atlas of lung cells, uncovering new cellular pathways and precursors in the development of lung adenocarcinoma, the most common type of lung cancer.

28 Feb 2024

Novel drug combination shows promise for treating advanced skin cancers in kidney transplant recipients

People who have had a kidney transplant are at high risk for developing skin cancers. New research directed by investigators from the Johns Hopkins Kimmel Cancer Center is exploring the best combination of treatments to target skin cancers while preserving the transplanted organs.

28 Feb 2024

Novel "Tissue-in-a-CUBE" model mimics blood-brain barrier for drug testing

A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has succeeded in establishing a model of the blood-brain barrier using modularized tissue derived from human cells.

28 Feb 2024

Universal, essential biomarker identified for childhood neuroblastoma

Researchers have newly identified a universal, essential biomarker for the childhood cancer neuroblastoma – and a potential new target for treatment.

27 Feb 2024

Study reveals distinct molecular features of proximal and distal colon cancers

The colon is often thought of as one organ, but the right and left parts of the colon have different molecular features in cancers.

27 Feb 2024

Breakthrough research could transform the landscape of ovarian cancer treatment

In a major scientific breakthrough, newly published research from an international consortium led by the University of Minnesota's Masonic Cancer Center has the potential to transform the landscape of ovarian cancer treatment.

27 Feb 2024

Study demonstrates a feasible way to expand germline genetic testing for cancer patients

A new University of Kentucky Markey Cancer Center study published in JCO Precision Oncology demonstrates a feasible way to expand germline genetic testing for patients with cancer.

27 Feb 2024

Study finds metabolic checkpoint PHGDH as potential target to modulate tumor-associated macrophages

A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in the top-class journal Cellular & Molecular Immunology, has a promising result from tumor research: The enzyme phosphoglycerate dehydrogenase (PHDGH) acts as a metabolic checkpoint in the function of tumor-associated macrophages (TAMs) and thus on tumor growth.

27 Feb 2024

Flavonol-rich diet linked to lower mortality and disease risk, study shows

Study finds that higher dietary intake of flavonol is linked to reduced all-cause mortality and lower risk of Alzheimer's disease, cancer, and cardiovascular disease in US adults.

26 Feb 2024

Study reveals early death predictors in COVID-19 patients with cardiac injury

Announcing a new article publication for Cardiovascular Innovations and Applications journal. The activation of immune and thrombotic biomarkers at admission, and their ability to predict cardiac injury and mortality patterns in COVID-19, remains unclear.

26 Feb 2024