Uric Acid News and Research

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Study reveals biochemical alterations in patients with Lesch-Nyhan disease

An international study by the Institute of Neuroscience of the UAB, Emory University and Hospital Universitario La Paz, published in the PNAS journal, shows that patients suffering from Lesch-Nyhan, a rare neurological disease, present biochemical alterations in skin cells (fibroblasts), urine and cerebrospinal fluid.

4 Jun 2020

The cost of excessive sugar in the diet

A new study from the MRC London Institute of Medical Sciences, in the UK, reports that while eating foods rich in sugar does not necessarily make you fat, they can make you very sick. They do this by increasing the level of a compound called uric acid in the blood. The study is published in the journal Cell Metabolism in March 2020.

19 Mar 2020

Dietary sugar has negative impact on health independent of obesity

Sugar-rich diets have a negative impact on health independent of obesity reports a new study led by the MRC London Institute of Medical Sciences, UK.

19 Mar 2020

Novel wireless sweat sensor can accurately detect stress levels

If someone asked you right now how stressed you are, what would you say? A little? A lot? You do not know?

26 Feb 2020

Salivary uric acid found to be a good predictor of body fat percentage in adolescents

In addition to helping us chew and swallow, keeping the mouth moist and protecting us against germs, saliva can also be used for early detection of the risk of developing diseases associated with surplus body fat.

18 Feb 2020

Antihypertensive drug associated with lower risk of gout

Affecting more than 7 million adults in the United States, gout is characterized by a sudden onset of pain, swelling and stiffness in the joints and caused by the formation of urate crystal in small spaces between joints that builds up when high amounts of uric acid circulate in the blood.

27 Jan 2020

New wearable sensor for non-invasive gout detection

Biomedical scientists are working hard to create more pain-free methods of disease detection and treatment. A simple blood test is highly informative but arouses intense anxiety in many people. Now a new paper published in the journal Nature Biotechnology on November 25, 2019, reports on a new wearable sensor that can be successfully adapted to mass production, is flexible, and can be used to produce readouts of metabolites and nutrients in the blood based on a sweat analysis.

26 Nov 2019

PERL study: Reducing uric acid levels does not benefit type 1 diabetes patients with kidney disease

Diabetic kidney disease remains one of the most intractable complications of diabetes. Progress has been made using glycemic and blood pressure control, but the search continues for improved treatments for the estimated one in four adults with diabetes who has some level of nephropathy and continues at risk for eventual kidney failure.

10 Nov 2019

Humanizing cell cultures

Today we know the function and metabolism of any mammalian cell depends on its environment. Such cells have long been cultured under conditions consisting of a basal medium with added nutritional serum. This, however, is not an accurate replica of the cell’s environment within the human body.

5 Nov 2019

Can Probiotics Support Healthy Kidney Function?

An interview with Dr Natarajan Ranganathan, key founder and Managing Director of Kibow Biotech Inc. about the use of probiotics for supporting healthy kidney function.

From Kibow Biotech Inc. 30 Oct 2019

Study evaluates hand-held technology to non-invasively fragment painful kidney stones

UC San Diego Health has enrolled its first patient to evaluate an investigational hand-held technology to non-invasively fragment painful kidney stones.

14 Oct 2019

New genome-wide association study shines light on genetic risk factors for gout

Researchers, using a method called genome-wide association study, have illuminated the genetic underpinnings of high serum urate, the blood condition that brings on gout.

7 Oct 2019

Short-term probiotic therapy regimen may improve symptoms of gout, kidney disease

New research suggests that an individualized probiotic therapy regimen may improve symptoms of gout, gout-related kidney disease and other signs of metabolic syndrome.

4 Oct 2019

Gout patients have higher risk of advanced kidney disease, study finds

Patients with gout are at increased risk of chronic kidney disease and kidney failure, according to new University of Limerick (UL), Ireland led research.

29 Aug 2019

Polycystic kidney disease may be preventable

Kidney failure is a lifelong burden in hundreds of thousands of people who need to be treated either by dialysis or a kidney transplant. Both procedures significantly increase the cost of healthcare and reduce the quality of life.

26 Aug 2019

Fruit fly model for studying diseases like gout, kidney stones reveals new drug targets

A new fruit fly model that mimics diseases associated with high uric acid levels, such as gout and kidney stones, has revealed new targets for developing treatments for these diseases.

From PLOS ONE 16 Aug 2019

Company expands development plans for drugs which slow progression to dialysis

Kibow Biotech announces that the focus on supporting and maintaining healthy kidney function with probiotics/prebiotics to potentially delay the progression to dialysis is based on its enteric toxin reduction platform technology termed "Enteric Dialysis®"

From Kibow Biotech Inc. 2 Aug 2019

Plastic ingestion can have a significant negative impact on healthy seabirds

An IMAS-led study of seabirds that had ingested plastic debris has revealed a range of non-lethal impacts on their health and physiology.

30 Jul 2019

Scientists discover how resistance to the chemotherapy drug 5-fluorouracil arises

Australian researchers have unlocked the mystery as to why the chemotherapy drug 5-Fluorouracil is not effective at treating certain cancers.

17 Jul 2019

Study reports significant link between exposure to inorganic dust and gout in women

The results of a study presented today at the Annual European Congress of Rheumatology demonstrate that occupational exposure to inorganic dust is a previously unknown risk factor for gout and also confirm known risk factors, such as alcoholism and obesity.

12 Jun 2019