Urinary Tract Infection News and Research

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Urinary tract infections are a serious health problem affecting millions of people each year. Infections of the urinary tract are the second most common type of infection in the body. Urinary tract infections (UTIs) account for about 8.3 million doctor visits each year.* Women are especially prone to UTIs for reasons that are not yet well understood. One woman in five develops a UTI during her lifetime. UTIs in men are not as common as in women but can be very serious when they do occur.

Novel technology set to play key role in the fight against anti-microbial resistance

Increasing pressures on health services have led to the over-prescription of commonly used antibiotics, more instances of mis-prescription and subsequently, the emergence of antibiotic resistance and an increased reliance on antibiotics of last resort.

5 Apr 2019

Presence of bacteria in urine does not always point to infection, shows study

Doctors should think carefully before testing patients for a urinary tract infection (UTI) to avoid over-diagnosis and unnecessary antibiotic treatment, according to updated asymptomatic bacteriuria (ASB) guidelines released by the Infectious Diseases Society of America (IDSA) and published in Clinical Infectious Diseases.

22 Mar 2019

Ball pits used in children's physical therapy may contribute to germ transmission

Beware the ball pit. Ball pits used in children's physical therapy - similar to those made popular by restaurants catering to families - may contribute to germ transmission between patients, according to new research published in the American Journal of Infection Control, the journal of the Association for Professionals in Infection Control and Epidemiology, published by Elsevier.

22 Mar 2019

First-in-human pilot study shows positive results for ‘bacteria-phobic’ catheter

Camstent Ltd., the company applying proprietary bacteria-phobic polymer coatings to medical devices, has been notified of initial results from the first-in-man pilot study for its CE marked coated catheter.

From Camstent Ltd. 21 Mar 2019

Mother's treatment for infection during pregnancy increases child's risk for autism and depression

Risks for autism and depression are higher if one's mother was in hospital with an infection during pregnancy. This is shown by a major Swedish observational study of nearly 1.8 million children.

8 Mar 2019

Bacteria-killing glass offers hope to combat deadliest hospital infections

Scientists at Aston University have discovered a technique similar to medieval stained glass-making that can completely eradicate the deadliest hospital infections within hours.

5 Mar 2019

ICHE’s reviews on surgical infections, unnecessary urine tests, and nurses' role in antibiotic stewardship

Changes to standard urine orders in a computer physician order entry (CPOE) system, resulted in a 45% reduction in unnecessary urine cultures ordered, a change that is expected prevent unnecessary treatment of asymptomatic patients whose bacteria counts are above normal.

22 Feb 2019

Thousands with chronic UTIs are not receiving the treatment they need

Many women may not be receiving the treatment they need because the gold-standard tests for UTIs fail to detect a significant proportion of bacteria.

21 Feb 2019

Combination of common antibiotics can eliminate multi-drug resistant E. coli

A group of scientists in Denmark is trying to get one step ahead in the battle against antibiotic resistance.

20 Feb 2019

In California, doctors accused of sexual misconduct often get second chances

The doctor instructed his patient to stand in front of him. He cupped her crotch and inserted his fingers into her vagina through her clothes, moving his hand repeatedly to her rectal area. Then he squeezed her breasts, according to a formal accusation filed by the Medical Board of California.

14 Dec 2018

Recurrence of urinary tract infection may depend on bacterial strain, study shows

Genetically diverse bacterial strains that cause urinary tract infections differ in their ability to trigger protective immune responses in mice, potentially explaining why these infections frequently recur in many patients, according to a study published December 13 in the open-access journal PLOS Pathogens by Thomas Hannan and Scott Hultgren of Washington University School of Medicine, and colleagues.

14 Dec 2018

Scientists unravel how bacterial persister cells manipulate our immune cells

New research, from scientists at Imperial College London, unravels how so-called bacterial persister cells manipulate our immune cells, potentially opening new avenues to finding ways of clearing these bacterial cells from the body, and stopping recurrence of the bacterial infection.

7 Dec 2018

New diabetes drugs linked to increased risk of lower-limb amputation and ketoacidosis

The use of a new class of drugs in the treatment of type 2 diabetes, so called SGLT2 inhibitors, are linked to a twofold increased risk for lower-limb amputation as well as diabetic ketoacidosis, a serious diabetes complication.

14 Nov 2018

Phase III CLL14 study evaluating Venclexta plus Gazyva to treat CLL meets its primary endpoint

Genentech, a member of the Roche Group , announced today that the randomized Phase III CLL14 study, which evaluated fixed-duration Venclexta® in combination with Gazyva® in people with previously untreated chronic lymphocytic leukemia and co-existing medical conditions, met its primary endpoint and showed a statistically significant reduction in the risk of disease worsening or death compared to standard-of-care Gazyva plus chlorambucil.

1 Nov 2018

Relapses are common in patients with drug-resistant urinary tract infections

Patients with a certain drug-resistant urinary tract infection were more likely to have a relapse of their infection within a week than those with non-resistant infections and were more likely to be prescribed an incorrect antibiotic according to a study published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

30 Oct 2018

The Lancet Infectious Diseases journal publishes clinical trial results for Shionogi’s cefiderocol

Shionogi & Co., Ltd. announced today that The Lancet Infectious Diseases journal has published clinical results from the pivotal randomized controlled trial evaluating cefiderocol for the treatment of complicated urinary tract infection in patients at risk of multidrug-resistant Gram-negative infections.

26 Oct 2018

Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer

Genentech, a member of the Roche Group, today announced positive results from the Phase III IMpower130 study of Tecentriq (atezolizumab) plus chemotherapy (carboplatin and Abraxane® [albumin-bound paclitaxel; nab-paclitaxel]) for the initial (first-line) treatment of people with previously untreated metastatic non-squamous non-small cell lung cancer.

22 Oct 2018

Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas

Merck, known as MSD outside the United States and Canada, today announced the first presentation of preliminary data from a Phase 1 clinical trial evaluating MK-1454, an investigational STING (stimulator of interferon genes) agonist, as monotherapy and in combination with KEYTRUDA (pembrolizumab), Merck's anti-PD-1 therapy, in patients with advanced solid tumors or lymphomas.

22 Oct 2018

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

Merck, known as MSD outside the United States and Canada, today announced the first presentation of results from an interim analysis of KEYNOTE-057, a Phase 2 trial evaluating KEYTRUDA, Merck's anti-PD-1 therapy, for previously treated patients with high-risk non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ or CIS plus papillary disease (Cohort A).

22 Oct 2018

ApoE4 gene linked with chronic inflammation increases risk for Alzheimer's disease

While it is widely shown that possessing the ApoE4 gene is the major genetic risk factor of Alzheimer's disease, not all ApoE4 carriers develop AD.

20 Oct 2018

Urinary Tract Infection News and Research

Further Reading

Novel technology set to play key role in the fight against anti-microbial resistance

Presence of bacteria in urine does not always point to infection, shows study

Ball pits used in children's physical therapy may contribute to germ transmission

First-in-human pilot study shows positive results for ‘bacteria-phobic’ catheter

Mother's treatment for infection during pregnancy increases child's risk for autism and depression

Bacteria-killing glass offers hope to combat deadliest hospital infections

ICHE’s reviews on surgical infections, unnecessary urine tests, and nurses' role in antibiotic stewardship

Thousands with chronic UTIs are not receiving the treatment they need

Combination of common antibiotics can eliminate multi-drug resistant E. coli

In California, doctors accused of sexual misconduct often get second chances

Recurrence of urinary tract infection may depend on bacterial strain, study shows

Scientists unravel how bacterial persister cells manipulate our immune cells

New diabetes drugs linked to increased risk of lower-limb amputation and ketoacidosis

Phase III CLL14 study evaluating Venclexta plus Gazyva to treat CLL meets its primary endpoint

Relapses are common in patients with drug-resistant urinary tract infections

The Lancet Infectious Diseases journal publishes clinical trial results for Shionogi’s cefiderocol

Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer

Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

ApoE4 gene linked with chronic inflammation increases risk for Alzheimer's disease

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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