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VEGF is a substance made by cells that stimulates new blood vessel formation. Also called vascular endothelial growth factor.

Research uncovers a new way to boost the effectiveness of RNA therapies

Investigators from the Smidt Heart Institute at Cedars-Sinai have identified how biological pacemaker cells-;cells that control your heartbeat-;can "fight back" against therapies to biologically correct abnormal heartbeat rates.

20 Dec 2022

Study proposes a new concept for treating COVID-19 associated weight loss

Losing too much weight when infected with COVID-19 has been linked to worse outcomes. Now, researchers at Karolinska Institutet in Sweden have discovered that SARS-CoV-2 infection fuels blood vessel formation in fat tissues, thus revving up the body's thermogenic metabolism.

9 Dec 2022

Study shows how dietary saturated/trans fats promote liver tumorigenesis

Fatty foods harm our health. Prior research has established a link between the consumption of dietary fats and non-alcoholic fatty liver disease, which subsequently leads to inflammation and tumor formation in the liver.

7 Dec 2022

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

Researchers reviewed technology advancements that will unlock the promise of biologically targeted messenger ribonucleic acid (mRNA) therapeutics beyond vaccines.

7 Nov 2022

Exploring SARS-CoV-2-associated endothelial dysfunction

A new study described the evidence, mechanisms, and therapies for endothelial dysfunction in coronavirus disease 2019 (COVID-19).

21 Oct 2022

Combination of three existing drugs extends survival in mouse models of lethal brain cancer

A Ludwig Cancer Research study has identified a combination of three existing drugs that significantly extends survival in mouse models of the lethal brain cancer glioblastoma multiforme (GBM).

20 Sep 2022

Is aspirin linked to higher rates of survival for cancer patients?

Researchers discussed the existing evidence on the use of acetylsalicylic acid (aspirin) in cancer treatment.

19 Sep 2022

Father of modern corneal science honored with the 2022 António Champalimaud Vision Award

Claes H. Dohlman, MD, PhD, whose pioneering research at Mass Eye and Ear and in the Department of Ophthalmology at Harvard Medical School (HMS) has forever changed the way conditions of the cornea are understood and treated, has been presented with the 2022 António Champalimaud Vision Award for his vast contributions to vision research.

15 Sep 2022

$Fruquintinib provides survival benefits for patients with refractory metastatic colorectal cancer$

Fruquintinib provides survival benefits for patients with refractory metastatic colorectal cancer

Researchers from The University of Texas MD Anderson Cancer Center reported study results showing that the targeted therapy fruquintinib significantly improved overall survival (OS) and progression-free survival (PFS) in patients with refractory metastatic colorectal cancer.

13 Sep 2022

A stepped regimen of anti-VEFG drugs leads to good vision outcomes in diabetic macular edema

Clinical trial results from the DRCR Retina Network suggest that a specific step strategy, in which patients with diabetic macular edema start with a less expensive medicine and switch to a more expensive medicine if vision does not improve sufficiently, gives results similar to starting off with the higher-priced drug.

14 Jul 2022

Moffitt researchers discover how YAP1 protein contributes to angiogenesis in cancers

The formation of new blood vessels, also known as angiogenesis, is critical to the development and progression of cancer.

8 Jul 2022

Fourth-generation vaping devices display a mix of cellular biomarkers indicative of immune suppression

Not all electronic cigarette devices are created equal. Some fourth-generation models – such as Juul devices – are associated with unique changes in markers of immune responses inside our airways.

5 Jul 2022

Proteins in the eye may predict which macular degeneration patients need life-long treatment

In a study of eye fluid from 38 patients, Johns Hopkins Medicine researchers say they have found that levels of a specific protein appears to help accurately predict whether people with the wet form of age-related macular degeneration may need lifelong, frequent eye injections to preserve vision or if they can be safely weaned off the treatments.

29 Jun 2022

Combination of three technologies makes potential treatment effective against aggressive brain tumor

A drug carrier able to reach the brain, bind to an aggressive type of tumor called glioblastoma multiforme, and release a chemotherapeutic agent has been tested for the first time by Brazilian researchers.

15 Jun 2022

Study reveals the benefits of using thalidomide in patients with severe arteriovenous malformations

The same properties that caused birth defects when it was given to pregnant women, the inhibition of blood vessel formation (anti-angiogenesis), have led to an interest in thalidomide's therapeutic utility in other fields.

10 Jun 2022

Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy

Researchers with The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute have identified a new molecular drug target that could result in new cancer drugs with fewer side effects.

20 May 2022

VEGF News and Research

Further Reading

Research uncovers a new way to boost the effectiveness of RNA therapies

Study proposes a new concept for treating COVID-19 associated weight loss

Study shows how dietary saturated/trans fats promote liver tumorigenesis

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

Exploring SARS-CoV-2-associated endothelial dysfunction

Combination of three existing drugs extends survival in mouse models of lethal brain cancer

Is aspirin linked to higher rates of survival for cancer patients?

Father of modern corneal science honored with the 2022 António Champalimaud Vision Award

Fruquintinib provides survival benefits for patients with refractory metastatic colorectal cancer

A stepped regimen of anti-VEFG drugs leads to good vision outcomes in diabetic macular edema

Moffitt researchers discover how YAP1 protein contributes to angiogenesis in cancers

Fourth-generation vaping devices display a mix of cellular biomarkers indicative of immune suppression

Proteins in the eye may predict which macular degeneration patients need life-long treatment

Combination of three technologies makes potential treatment effective against aggressive brain tumor

Study reveals the benefits of using thalidomide in patients with severe arteriovenous malformations

Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy

MAPK pathway mutations can provide “precision” treatment targets for head and neck cancer

Treatment for retinal vein occlusion yields long-lasting vision gains, study shows

Exploring strategies for successful delivery of messenger RNA therapeutics

Curcumin released from magnetic hydrogels promotes the secretion of vascular endothelial growth factor

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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