VEGF News and Research

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VEGF is a substance made by cells that stimulates new blood vessel formation. Also called vascular endothelial growth factor.

Two novel therapies for multiple myeloma

Two novel biologics are currently being investigated for their potential benefit to multiple myeloma patients in separate ongoing clinical trials at NewYork-Presbyterian Hospital/Weill Cornell Medical Center.

14 Mar 2007

Ink-jet printing of bone

A modified ink-jet printer can be used to directly print layer upon layer of artificial bone for quick-fix grafts used in reconstructive surgery.

4 Mar 2007

Sunitinib halts progress of metastatic kidney cancer

Research has shown the efficacy of a pharmaceutical drug known as sunitinib which halts progress of metastatic kidney cancer.

1 Mar 2007

Avastin slows growth of gliomas

Avastin, a relatively new type of drug that shrinks cancerous tumors by cutting off their blood supply, can slow the growth of the most common and deadly form of brain cancer, a pilot study conducted at Duke University Medical Center has found.

20 Feb 2007

Dll4 signalling through Notchi regulates formation of tip cells during angiogenesis

All tissues, sick and healthy alike, need a blood supply to survive and grow. The key to many medical problems, like preventing tumour development, is therefore to obstruct the spread of the blood vessels. Research scientists at Karolinska Institutet have now discovered a heretofore unknown mechanism for how the body links together its blood vessels.

29 Jan 2007

Targeted nanoparticles to improve Boron-Neutron capture therapy

Boron-neutron capture therapy (BNCT) is an experimental treatment for virulent brain cancer that aims to kill malignant cells by generating high-energy alpha particles inside tumors.

5 Sep 2006

Cancer stem cells spur glioma angiogenesis, could hold key to brain tumor therapy

Stem cell-like glioma cancer cells that share many characteristics with normal stem cells propel the lethal growth of brain cancers by promoting tumor blood vessel formation, and may hold the key to treating these deadly cancers.

15 Aug 2006

New findings support Rapamycin's role as cancer treatment

Scientists have long known that the blood vessels of tumors differ markedly from normal blood vessels.

14 Aug 2006

Sonic hedgehog may help overcome problems associated with FGF2 and VEGF therapy

The newest concept for treating coronary artery disease is to induce hearts to grow their own new blood vessels to bypass damaged tissue or clogged arteries.

18 Jun 2006

Discovery of protein associated with severe preeclampsia

Researchers have identified a second protein which, in combination with sFlt1, escalates preeclampsia to a severe - and life-threatening - state.

6 Jun 2006

Blood pressure drugs associated with reduced risk of cancers

Thousands of individuals currently taking angiotension converting enzyme (ACE) inhibitors, a type of medication commonly used to lower blood pressure, may be doing more than treating their hypertension.

31 May 2006

Promising chemo, therapeutic viruses, cutting-edge surgery debut at M. D. Anderson Cancer Center

Brain tumor specialists at The University of Texas M. D. Anderson Cancer Center are poised on the brink of a new era.

10 May 2006

New discovery about role of sugar in cell communication

A research team from Uppsala University has uncovered an entirely new mechanism for how communication between cells is regulated.

9 May 2006

Placental growth factor may help body repair heart attack damage

Heart attack patients produce higher levels of a natural substance in the body that plays a role in the growth of new blood vessels and this over-expression of placental growth factor (PlGF) may help reduce damage to the heart muscle

17 Apr 2006

Fat cells surrounding coronary arteries may play a role in development of heart disease

The fat cells that surround coronary arteries may play a central and previously unrecognized role in development of cardiovascular disease, according to a study by University of Iowa researchers.

11 Apr 2006

Moderate alcohol intake stimulates tumor angiogenesis and expression of vascular endothelial growth factor in a mouse model

University of Mississippi researchers say they have created the first-ever mammalian model of how alcohol consumption spurs tumor growth, showing that even moderate drinking resulted in larger and more robust tumors.

4 Apr 2006

Trial of paclitaxel with or without bevacizumab as first-line therapy for locally recurrent or metastatic breast cancer

Results from a large, randomised clinical trial for patients with breast cancer show that those who received bevacizumab (Avastin.) in combination with paclitaxel (Taxol.) survived without the disease getting worse for almost twice as long as patients who received paclitaxel alone.

23 Mar 2006

Thrombocytosis: A clinical marker of tumor aggressiveness in renal cell carcinoma

Molecular and serum markers of prognosis in renal cell carcinoma have remained elusive. In large part, tumor (TNM) stage, Fuhrman grade, and patient performance status have stood the test of time as the most valuable factors in predicting patient outcome following surgery.

15 Mar 2006

Study may lead to ways to reduce heart attacks in diabetes patients

For people with type 2 diabetes, the death rate from a first heart attack is two to three times the death rate of patients without the disease. Similarly, patients with diabetes and ischemic (reduced blood flow) heart disease have a much higher mortality rate than the general population.

7 Mar 2006

Avastin trial for pancreatic tumors

"Our findings from the previous study suggest that the combination of chemotherapy and radiation is a safe and effective treatment method to reduce the local extent of pancreatic tumors," said Dr. Talamonti.

23 Feb 2006