Vagina News and Research

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Transvaginal placement of surgical mesh for pelvic organ prolapse may pose greater risk, warns FDA

The U.S. Food and Drug Administration today issued an updated safety communication warning health care providers and patients that surgical placement of mesh through the vagina to repair pelvic organ prolapse may expose patients to greater risk than other surgical options.

14 Jul 2011

Sexually transmitted diseases more common in women age 40

A Johns Hopkins infectious disease expert is calling for all sexually active American women age 40 and older to get tested for the parasite Trichomonas vaginalis after new study evidence found that the sexually transmitted disease (STD) is more than twice as common in this age group than previously thought.

12 Jul 2011

Covidien to support NOTES human trial on transoral, transvaginal cholecystectomies

The Natural Orifice Surgery Consortium for Assessment and Research- (NOSCAR-), a joint effort of the American Society for Gastrointestinal Endoscopy and the Society of American Gastrointestinal and Endoscopic Surgeons, is pleased to announce a grant from Covidien to support the U.S. multicenter human trial on transoral and transvaginal cholecystectomies using Natural Orifice Translumenal Endoscopic Surgery.

11 Jul 2011

New clinical trial to evaluate safety of tenofovir gel in breastfeeding, pregnant women

Determining whether a promising HIV prevention gel is safe for women to use while they are pregnant or breastfeeding is the aim of a new clinical trial being conducted by the National Institutes of Health-funded Microbicide Trials Network.

21 Jun 2011

NIH-funded study to develop virtual reality simulator for 'scarless' endoscopic surgery

Researchers at Rensselaer Polytechnic Institute have secured a $2.7 million grant to develop the first-ever virtual reality simulator for next-generation "scarless" endoscopic surgery.

20 Jun 2011

AHRQ: 94% of women hospitalized for pregnancy and delivery in the U.S. had complications

Over 9 out of every 10 women giving birth in the United States had some complication in 2008, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

27 May 2011

Study: Healthy gut flora reduces risk of obesity and body's low-level inflammation

Poor gut flora is believed to trigger obesity. In the same way, healthy gut flora could reduce the risk. This has shown to be the case in tests on rats.

26 May 2011

Loss of elasticity and protein breakdown cause pelvic organ prolapse

A gynecologist and a molecular biologist at UT Southwestern Medical Center have collaborated to show for the first time that pelvic organ prolapse - a condition in which the uterus, bladder or vagina protrude from the body - is caused by a combination of a loss of elasticity and a breakdown of proteins in the vaginal wall.

24 May 2011

Australians discover treatment for very common female infection

Starpharma Holdings Limited has announced successful results of a major phase 2 clinical study that demonstrated efficacy of VivaGel® for the treatment of bacterial vaginosis (BV).

22 May 2011

Mesh surgery more effective for patients with pelvic organ prolapse

A Nordic multicentre study, headed by researchers from Karolinska Institutet in Sweden, shows that pelvic organ prolapse surgery using synthetic mesh can be more effective than traditional surgery.

12 May 2011

Fibulin-5 protein can help prevent pelvic organ prolapse development in women

Pelvic organ prolapse is a disabling condition that affects almost 50% of women over the age of 50. It occurs when the muscles and ligaments supporting a woman's pelvic organs weaken such that the pelvic organs slip out of place, often protruding into the vagina.

26 Apr 2011

Squamous cell cancers can originate from hair follicle stem cells, finds study

Squamous cell cancers, which can occur in multiple organs in the body, can originate from hair follicle stem cells, a finding that could result in new strategies to treat and potentially prevent the disease, according to a study by researchers with UCLA's Jonsson Comprehensive Cancer Center and the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA.

20 Apr 2011

Researchers to wind down HIV prevention trial in women after interim results find drug not offering protection from HIV

Researchers on Monday announced they were calling off a trial to test whether taking an oral HIV drug reduces the risk of HIV infection in women after interim analysis of the study showed women taking the medication were no less likely to become infected with HIV than those who were not taking the medicine, the Associated Press reports.

20 Apr 2011

First ever light-activated, non-surgical treatment for HPV and pre-cancerous lesions of the cervix

A new non-surgical, tissue-preserving therapeutic procedure is being developed to more effectively remove HPV infection and treat precursors of cervical cancer.

16 Mar 2011

Organ removal surgery through body's orifices, without any visible incisions

The Chicago Park District physical instructor needed a way to get the surgery performed without being laid up for weeks so she opted for an innovative minimally invasive procedure called Natural Orifice Translumenal Endoscopic Surgery (NOTES) that would allow surgeons to perform organ removal surgery without any visible incisions and have her back on her feet the same day.

11 Mar 2011

Tenofovir gel more effective than oral tablet for HIV treatment: Study

In the first study to make head-to-head comparisons between tenofovir gel and oral tenofovir - two promising approaches for preventing HIV in women - researchers found that daily use of the vaginal gel achieved a more than 100-times higher concentration of active drug in vaginal tissue than did the oral tablet, while, compared to the gel, the tablet used daily was associated with a 20-times higher active drug concentration in blood.

1 Mar 2011

Anti-AIDS gel shows promise

Dr. Ian McGowan, a professor of medicine at the University of Pittsburgh who is leading a second-phase study of the gel said, “These are early results, but [they] help set the stage for current and future trials of rectal microbicides and the development of a rectal-specific formulation of tenofovir gel.” Researchers have focused on the use of microbicides such as tenofovir, as a preventive treatment to be used in vaginal sex. However, scientists think unprotected anal sex is much more risky.

1 Mar 2011

Tenofovir gel may help reduce risk of HIV from anal sex

A gel developed to protect against HIV during vaginal sex produced a strong antiviral effect when used in the rectum, according to an early-phase study presented today at the 18th Conference on Retroviruses and Opportunistic Infections (CROI). The results, based on rectal tissue biopsies sampled from HIV-negative men and women who used the product daily for one week, provide the first-ever evidence that tenofovir gel could help reduce the risk of HIV from anal sex, even though the vaginal gel formulation may not be optimal for rectal use.

28 Feb 2011

ITM research provides deep insight into interactions between HIV virus and human cells

Over the years, the AIDS virus has increasingly adapted itself to humans. This is shown by the research of Youssef Gali at the Institute of Tropical Medicine.

15 Feb 2011

Proellex vaginal delivery exhibits four times activity of oral dose in animal study

Repros Therapeutics Inc. today announced it has completed two animal model studies of the use of Proellex® in a vaginally administered formulation that demonstrated effects on progesterone sensitive tissues equivalent to the highest oral dose formerly in development by the Company.

28 Dec 2010