Valproic Acid News and Research

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Valproic Acid is a drug used to treat epileptic seizures and bipolar disorder and to prevent migraine headaches. It is also being studied in the treatment of Kaposi sarcoma. It is a type of anticonvulsant, antimaniacal, and migraine headache prophylactic.

Licensing arrangement reached for antiepileptic drug developed at Hebrew University

A worldwide licensing arrangement for development, production and marketing of an antiepileptic drug created at the Hebrew University of Jerusalem has been signed by Shire Pharmaceuticals with Yissum, the Hebrew University's technology transfer company.

5 Sep 2006

Environmental scientists identify new culprits in the cancer equation

In the granite-rich region of Western North Carolina, taking a daily shower could pose a risk of developing lung cancer. So could working from home every day. That's because granite emits a carcinogenic gas, radon.

13 Apr 2006

Valproic acid may help slow the progression of dementia

Researchers have found that a common anticonvulsant drug improved cognitive function and appeared to restore nerve cells in the brains of patients with HIV-related dementia. The results of the Phase I clinical trial are published in the March issue of the scientific journal Neurology.

14 Mar 2006

Repligen commences phase 2 trial of RG2417 for bipolar depression

Repligen Corporation today announced that the Company has initiated a Phase 2 clinical trial of RG2417, an oral formulation of uridine, in patients with bipolar depression.

9 Mar 2006

$1 million of mesothelioma research funding

The Mesothelioma Applied Research Foundation (MARF) has announced awards of almost $1 million in additional research funding aimed at curing mesothelioma.

24 Feb 2006

Valproic acid (Depakote) may help treat lupus

A common anti-seizure drug may be effective against certain conditions associated with lupus, according to animal research at Wake Forest University School of Medicine.

20 Nov 2005

Scientists say valproic acid can eradicate dormant HIV

Early research by scientists in the U.S. suggests that valproic acid could be a potential way to eradicate dormant HIV infections.

14 Aug 2005

New therapeutic approach that could help eliminate dormant HIV infection

US scientists have tested a new therapeutic approach that could help eliminate dormant HIV infection that current treatments miss. The researchers report these preliminary findings in a proof-of-concept study in this week’s issue of The Lancet.

11 Aug 2005

Why good medications are sometimes bad for the liver

The University of North Carolina at Chapel Hill is one of five clinical centers nationwide to receive funds from the National Institutes of Health to study why good medications are sometimes bad for the liver.

29 May 2005

Testing new manic depression drugs in slime mould

Research by University College London (UCL) scientists could lead to the development of more effective drugs for treating manic depression thanks to a new screening approach developed in a "slime mould" - a microbe that lives in leaves and dung on forest floors.

23 Apr 2005

Mixed results on the effects of epilepsy drugs taken during pregnancy

New studies show mixed results on the effects of epilepsy drugs taken during pregnancy. With a newer drug, lamotrigine, the risk of birth defects was similar to that in women without epilepsy. But long-time epilepsy drug valproic acid, or sodium valproate, does increase the risk of birth defects.

22 Mar 2005

The good news and the bad news on epilepsy drugs for pregnant women

Two new studies on the effects of epilepsy drugs taken during pregnancy show mixed results. The risk of birth defects with a newer drug, lamotrigine, was similar to that in women without epilepsy.

21 Mar 2005