Vascular News and Research

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The burden of diabetes in heart disease in Europe

Diabetes is becoming one of the major health problems in the European and US populations. It is frequently associated with overweight, hypertension and high serum cholesterol levels, representing a dangerous combination of risk factors for the development of heart and vascular diseases.

2 Sep 2007

Blood pressure drugs cut death rate in diabetes

The largest-ever study of treatments for diabetes has shown that a fixed combination of two blood pressure lowering drugs reduces the risk of death, as well as the risks of heart and kidney disease. Results from the ADVANCE (Action in Diabetes and Vascular Disease) Study were presented today at the European Society of Cardiology Congress 2007 in Vienna.

2 Sep 2007

Does physical activity provide a molecular key to longevity?

Fitness and physical exercise are among the most neglected means to improve prognosis. They are the healthiest cardiovascular intervention. Even cardiologists focus on pharmacological treatment and evaluate classical risk factors without asking about daily exercise or objective measures of physical capacity. It is surprising considering the strong data that underscores the survival benefit of regular exercise training.

2 Sep 2007

COPD can no longer be judged as only a disease of the lungs

Chronic Obstructive Pulmonary Disease (COPD) can no longer be judged as only a disease of the lungs, say authors of a Viewpoint in this week's COPD special edition of The Lancet.

30 Aug 2007

Big leap in genomic screening of blood vessels from patient tissue

Scientists have developed a new method of capturing a complete genome-wide screening of blood vessel cells in their actual disease state, advancing the potential for genetic research on the tissue responsible for delivering nourishment that can accelerate the growth of both a cancer tumor or wound healing.

30 Aug 2007

Early heart treatment can reverse damage

University of Minnesota researchers have discovered that treating people who have early cardiovascular abnormalities, but show no symptoms of cardiovascular disease, can slow progression and even reverse damage to the heart and blood vessels.

28 Aug 2007

HSP 90 inhibitors may help ICU patients beat infections

HSP 90 inhibitors, which are finding favor in fighting cancer, may also help battle overwhelming infection in intensive care patients, researchers say.

28 Aug 2007

Cholesterol-lowering statins may also reduce the risk of Alzheimer's

Researchers in the United States say they believe cholesterol-lowering drugs may reduce the risk of Alzheimer's.

28 Aug 2007

Australian researchers discover a 'novel molecular dictator with a conscience'

University of New South Wales (UNSW) researchers have uncovered an important naturally occurring mechanism in the body where "bad" cells that cause blockages in our blood vessels are kept under strict growth control, while "good" cells that keep our blood vessels free of clots and growths are left unaffected.

27 Aug 2007

Blocking angiogenesis signaling from inside cell may lead to serious health problems

Angiogenesis inhibitors that block a tumor's development of an independent blood supply have been touted as effective cancer fighters that result in fewer side effects than traditional chemotherapy.

24 Aug 2007

Call for improved treatments of stroke

A coalition of physicians representing a wide range of medical specialties has issued a call to action to improve the treatment of stroke.

22 Aug 2007

Genetic testing can be used to help personalize the therapeutic dosage of warfarin

Genetic testing can be used to help personalize the therapeutic dosage of warfarin, a commonly-used anticoagulant, according to research published in the September 1, 2007, issue of Blood, the journal of the American Society of Hematology.

21 Aug 2007

Sex differences in response to vasoactive substances in early uncontrolled diabetes

Diabetes is associated with the development of vascular (blood vessel) disease. As we age, vascular disease becomes more common.

17 Aug 2007

Cytokines shown to be a cause of type 2 diabetes

In the first large scale, multiethnic study of its kind, researchers at UCLA have confirmed the role played by three particular molecules known as cytokines as a cause of Type 2 diabetes, and further, have identified these molecules as early biological markers that may be used to more accurately predict future incidences of diabetes among apparently healthy individuals.

16 Aug 2007

New pathway for inflammation-induced cancer

A well-known inflammatory protein spawns an enzyme that inactivates two tumor-suppressing genes, ultimately triggering production of new blood vessels to nourish breast cancer cells, researchers at The University of Texas M. D. Anderson Cancer Center report in the August edition of the journal Cell .

11 Aug 2007

Gender differences in renal and other genes contributing to blood pressure

Many common diseases exhibit gender bias and gender differences have been observed in the development of high blood pressure (hypertension) and heart (cardiovascular) disease.

9 Aug 2007

Vitamin B1 deficiency key to vascular problems for diabetic patients

Researchers at Warwick Medical School, University of Warwick, have discovered that deficiency of thiamine - vitamin B1 - may be key to a range of vascular problems for people with diabetes.

8 Aug 2007

Endothelial nitric oxide synthase gene linked to brain aneurysm formation

University of Cincinnati (UC) neurovascular researchers have identified a gene that, when suppressed or completely absent, may predispose a person to brain aneurysms.

8 Aug 2007

Statin drugs may delay progressive artery damage in children

Starting statin therapy as young as age 8 safely and effectively delays the early artery damage caused by familial hypercholesterolemia (FH), according to a Dutch study reported in the Aug.7th print issue of Circulation: Journal of the American Heart Association.

7 Aug 2007

New device to treat chronic congestive heart failure

As part of a 40-site national trial, researchers at UT Southwestern Medical Center are studying a new medical device designed to treat patients with chronic congestive heart failure.

3 Aug 2007