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Researchers suggest potential new way to restore healthy intestinal function in older people

Intestinal stem cells rejuvenate daily so bowels will stay healthy and function normally, but a new study in Cell Reports suggests they also age along with people and lose their regenerative capacity.

15 Mar 2017

Experts develop new method to quantify syncytial knots in placenta

Identifying potential risk factors that may harm placental development is a primary objective of pregnancy screenings. To help ensure healthy pregnancies and, in turn, healthy newborns, researchers and clinicians continue to develop new and innovative testing methods to monitor fetal development.

17 Nov 2016

Identifying foods that trigger IBS: an interview with Dr Bill Chey

IBS is a common medical condition which is diagnosed in the presence of characteristic gastrointestinal symptoms including recurring bouts of abdominal pain and diarrhea and/or constipation. IBS patients also commonly report bloating and abdominal distension or swelling.

15 Nov 2016

Mitochondria regulates stem cell proliferation in gut epithelium, study shows

What happens in intestinal epithelial cells during a chronic illness? Basic research conducted at the Chair of Nutrition and Immunology at the Technical University of Munich addressed this question by generating a new model system.

27 Oct 2016

Researchers identify epigenetic mechanism causing aberrancies in coeliac disease

Researchers at the University of Tampere discovered a mechanism causing aberrancies in coeliac disease and colorectal cancer.

5 Sep 2016

Penn researchers help identify unique characteristics of reserve stem cells

Adult stem cells represent a sort of blank clay from which a myriad of different cell and tissue types are molded and as such are of critical importance to health, aging and disease.

16 Jun 2016

Tackling healthcare challenges in a changing world: an interview with Professor Jeremy Nicholson

As individuals and as populations our risks of getting diseases are determined partly genetically and partly from the environment that we live in. An important part of that environment that mediates between the outside world and the inside world of our bodies is the microbiome.

10 Jun 2016

Gut microbiome can play significant role in the body's response to gluten

Investigators interested in celiac disease, a chronic gastrointestinal disorder caused by an immunologic response to the ingestion of gluten, have wondered why only 2% to 5% of genetically susceptible individuals develop the disease.

8 Oct 2015

Researchers develop new blood test to diagnose coeliac disease

Diagnosis of coeliac disease requires a tissue sample from the small intestine, which can be extremely unpleasant. Researchers at the Faculty of Medicine have developed a blood test which provides a rapid, painless answer.

25 Sep 2015

Small intestine causes chronic inflammation in obese patients

Obesity is caused by numerous and complex factors, some of which are as yet unsuspected. Scientists from the CNRS, INSERM, UPMC and Université Paris Descartes, working with research clinicians from Paris Public Hospitals (AP-HP) have now shown that severe obesity is accompanied by inflammation of the small intestine and enhanced immune response in that region.

22 Jun 2015

Snai1 protein plays major role in deciding fate of intestinal stem cells

An international group of researchers has shown that a regulatory protein involved in controlling how cancer spreads through the body also influences the fate of stem cells in the intestine of mice. The results, which are published in The EMBO Journal, show that the Snai1 protein plays an important role in deciding the fate of intestinal stem cells and the different functions that these cells can adopt.

10 Mar 2015

Gluten-free diet important for people with celiac disease

You'd never suspect it from the proliferation of gluten-free items on supermarket shelves. Yet only one in approximately 133 people - that's 0.75 percent of the population - has celiac disease, a genetic autoimmune disorder that causes the body to react negatively to the intake of gluten, a protein found in wheat, rye, barley and their derivatives.

29 Jan 2015

Fecal occult blood screening increases diagnosis rate of high-risk polyps by 89%

The introduction of biennial colorectal cancer screening in a region of France increased the rate of diagnosis of high risk pre-cancerous adenomas (sometimes called polyps) by 89%, researchers have reported at the ESMO 2014 Congress in Madrid.

29 Sep 2014

Alba Therapeutics reports positive results from Phase IIb trial of larazotide acetate for CeD treatment

Alba Therapeutics Corporation announced today the positive results of their Phase IIb trial evaluating its investigational product, larazotide acetate, a first-in-class tight junction regulator, intended for the treatment of patients with celiac disease (CeD).

11 Feb 2014

Celiac disease patients with persistent intestine damage are at higher risk of lymphoma

Patients with celiac disease who had persistent intestine damage (identified with repeat biopsy) had a higher risk of lymphoma than patients whose intestines healed, according to findings published in the August 6, 2013, issue of Annals of Internal Medicine.

6 Aug 2013

GF foods lack vitamins and nutrients, can be high in fat and calories

In the ever-present search to identify and address bad nutrition habits, gluten-free eating has been receiving a lot of attention. But experts at the University of Alabama at Birmingham (UAB) say it is not to be confused with typical weight loss procedures.

29 Mar 2013

Study investigates new way to treat necrotizing enterocolitis

Stem cells taken from amniotic fluid were used to restore gut structure and function following intestinal damage in rodents, in new research published in the journal Gut.

25 Mar 2013

Oleuropein aglycone reduces inflammation associated with intestinal ischemia and reperfusion

Here's another reason why you should include olive oil in your diet: A new research report published in the Journal of Leukocyte Biology suggests that at least one compound in olive oil significantly reduces intestinal ischemia (restricted blood supply) and the resulting reperfusion injury (tissue damage caused when blood supply returns).

6 Feb 2013

Previously unknown mechanism helps intestinal bacteria to affect formation of blood vessels

Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have discovered a previously unknown mechanism which helps intestinal bacteria to affect the formation of blood vessels. The results, which are presented in Nature, may provide future treatments of intestinal diseases and obesity.

27 Mar 2012

Previously unknown mechanism helps intestinal bacteria to affect formation of blood vessels

26 Mar 2012

Villi News and Research

Researchers suggest potential new way to restore healthy intestinal function in older people

Experts develop new method to quantify syncytial knots in placenta

Identifying foods that trigger IBS: an interview with Dr Bill Chey

Mitochondria regulates stem cell proliferation in gut epithelium, study shows

Researchers identify epigenetic mechanism causing aberrancies in coeliac disease

Penn researchers help identify unique characteristics of reserve stem cells

Tackling healthcare challenges in a changing world: an interview with Professor Jeremy Nicholson

Gut microbiome can play significant role in the body's response to gluten

Researchers develop new blood test to diagnose coeliac disease

Small intestine causes chronic inflammation in obese patients

Snai1 protein plays major role in deciding fate of intestinal stem cells

Gluten-free diet important for people with celiac disease

Fecal occult blood screening increases diagnosis rate of high-risk polyps by 89%

Alba Therapeutics reports positive results from Phase IIb trial of larazotide acetate for CeD treatment

Celiac disease patients with persistent intestine damage are at higher risk of lymphoma

GF foods lack vitamins and nutrients, can be high in fat and calories

Study investigates new way to treat necrotizing enterocolitis

Oleuropein aglycone reduces inflammation associated with intestinal ischemia and reperfusion

Previously unknown mechanism helps intestinal bacteria to affect formation of blood vessels

Previously unknown mechanism helps intestinal bacteria to affect formation of blood vessels

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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