immunity News and Research

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UK Aid awards funding to Oxford Vaccine Group for research into prevention of five epidemic threats

Oxford Vaccine Group (OVG), which led the rapid clinical development of the Oxford vaccine in COVID-19 in the pandemic, has been awarded a total of £7,788,783 by UK Aid for research into the prevention of five dangerous diseases with epidemic or pandemic potential.

13 Dec 2023

RBD-focused vaccines may offer broader protection against emerging COVID-19 variants

Published in The Lancet's eBioMedicine, 76 healthy adults from Melbourne, aged 18 to 64 who were previously vaccinated with licensed SARS-CoV-2 vaccines, were randomized to receive a fourth dose of a novel protein vaccine, mRNA vaccine or placebo.

12 Dec 2023

Evaluation of immunogenicity-induced DNA vaccines against different SARS-CoV-2 variants

Five DNA vaccine candidates based on different SARS-CoV-2 strains.

12 Dec 2023

New SARS-CoV-2 variant JN.1 shows increased transmissibility and immune resistance

A Japanese study published in BioRxiv explores the virological characteristics of the SARS-CoV-2 JN.1 variant, finding it has a higher effective reproductive number and stronger resistance to immunity from other variants, potentially due to the L455S spike protein mutation.

11 Dec 2023

Key role of ion and water influx in T cell migration uncovered

Research reveals that T cell migration relies on ion and water influx for actin polymerization and movement, with the WNK1 kinase playing a critical role in regulating these processes, offering new insights into adaptive immunity.

10 Dec 2023

Researchers discover next-gen lipid nanoparticles for muscle-focused mRNA delivery

A team of researchers based at the University of Toronto's (U of T) Leslie Dan Faculty of Pharmacy has discovered a novel ionizable lipid nanoparticle that enables muscle-focused mRNA delivery while minimizing off-target delivery to other tissues.

8 Dec 2023

T cells can recognize and fight the "Pirola" variant, new study suggests

In August, researchers detected a new SARS-CoV-2 "variant of concern" in patients in Israel and Denmark.

8 Dec 2023

Repeated mRNA vaccines supercharge immune response against COVID-19, study finds

Study published in Nature Immunology reveals that repeated mRNA COVID-19 vaccinations enhance immune response, especially in previously infected individuals, leading to a diversified and increased number of immune cell clones and a stronger ability to combat various virus strains.

7 Dec 2023

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

Study explores immunoregulatory nanomedicines for respiratory infections, highlighting their potential in enhancing treatment outcomes and vaccine efficacy.

7 Dec 2023

Researchers discover how bexmarilimab activates immune cells against tumors

Researchers at the University of Turku, Finland, have uncovered how the new bexmarilimab therapy alters the function of immune cells so that they can infiltrate the tumor in cancer patients who do not respond to any other current therapies.

7 Dec 2023

Immune system shows remarkable adaptability to SARS-CoV-2 variants

Although SARS-CoV-2 is no longer a stranger to the immune system, new virus variants still pose a challenge.

7 Dec 2023

Birth control pills may alter stress response, increase inflammation risk, study suggests

A new UCLA Health study is shedding light on how using hormonal contraceptive pills may affect women's responses to stress and their risk for inflammation-related illnesses.

7 Dec 2023

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into mRNAs affects ribosomal frameshifting and the overall fidelity of mRNA translation.

7 Dec 2023

Blocking an allergy pathway unleashes antitumor immunity in mouse models of non-small cell lung cancer

Researchers at the Icahn School of Medicine at Mount Sinai have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of non-small cell lung cancer (NSCLC).

6 Dec 2023

Design modifications offer promise for safer and more effective mRNA therapeutics

Researchers have discovered that misreading of therapeutic mRNAs by the cell's decoding machinery can cause an unintended immune response in the body.

6 Dec 2023

Study links elevated BMI to weaker immune response post-SARS-CoV-2 infection

Researchers evaluated the impact of BMI elevation on humoral immunity levels against SARS-CoV-2.

6 Dec 2023

Research uncovers stealthy strategy of SARS-CoV-2 infection

Researchers have discovered a novel mechanism whereby the SARS-CoV-2 virus, which causes COVID-19, can vary its mode of infection in human cells. Published in the journal eLife, a team from the University of Minnesota and the Midwest Antiviral Drug Discovery (AViDD) Center found the virus can alternate between being highly infectious and avoiding detection by the immune system.

5 Dec 2023

immunity News and Research

UK Aid awards funding to Oxford Vaccine Group for research into prevention of five epidemic threats

RBD-focused vaccines may offer broader protection against emerging COVID-19 variants

Evaluation of immunogenicity-induced DNA vaccines against different SARS-CoV-2 variants

New SARS-CoV-2 variant JN.1 shows increased transmissibility and immune resistance

Key role of ion and water influx in T cell migration uncovered

Researchers discover next-gen lipid nanoparticles for muscle-focused mRNA delivery

T cells can recognize and fight the "Pirola" variant, new study suggests

Repeated mRNA vaccines supercharge immune response against COVID-19, study finds

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

Researchers discover how bexmarilimab activates immune cells against tumors

Immune system shows remarkable adaptability to SARS-CoV-2 variants

Birth control pills may alter stress response, increase inflammation risk, study suggests

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Blocking an allergy pathway unleashes antitumor immunity in mouse models of non-small cell lung cancer

Design modifications offer promise for safer and more effective mRNA therapeutics

Study links elevated BMI to weaker immune response post-SARS-CoV-2 infection

Research uncovers stealthy strategy of SARS-CoV-2 infection

Common dietary supplement could protect against chronic Cryptosporidium infections

Overweight people may have impaired antibody response to COVID-19 infection

MU researchers unveil the immune system's secret weapon against lung cancer

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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