immunity News and Research

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New trial of a preventive HIV vaccine candidate begins in the United States and South Africa

A trial of a preventive HIV vaccine candidate has begun enrollment in the United States and South Africa.

20 Sep 2023

Scientists develop Australia’s first-of-its-kind next-gen mpox diagnostic tool

In a collaborative study published in The Lancet Microbe, the team of scientists, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute) and WEHI (Walter and Eliza Hall Institute of Medical Research), revealed MPXV-CRISPR – a powerful diagnostic tool capable of detecting MPXV in clinical samples with acute precision and at a faster rate than any other method, thanks to the power of CRISPR technology.

20 Sep 2023

Vaccine impact: BNT162b2 and pediatric COVID-19 ambulatory visits in kids under 5

The association between BNT162b2 vaccine and (COVID-19)-related ambulatory visits.

20 Sep 2023

Age and underlying conditions increase risk of critical outcomes for hospitalized COVID-19 patients

Whether vaccinated or not, having at least four disease risk factors put adults hospitalized due to COVID-19 at higher risk for critical outcomes, according to a 10-state study from the Centers for Disease Control and Prevention's (CDC's) VISION Network.

19 Sep 2023

Tufts Lyme Disease Initiative receives $7M in grants to advance research to next level

Researchers at the Tufts Lyme Disease Initiative recently received grants totaling more than $7 million to build on an already impressive array of discoveries that Tufts' teams have made to combat tick-borne diseases.

19 Sep 2023

High-intensity exercise may reduce colorectal cancer risk in Lynch Syndrome patients

Regular and intense aerobic exercise may reduce the risk of colorectal cancer in patients with Lynch Syndrome (LS) by improving the immune system's ability to detect and remove potentially harmful cells, according to researchers at The University of Texas MD Anderson Cancer Center.

19 Sep 2023

Research demonstrates a double-acting mechanism for fighting triple-negative breast cancer

Zachary Schug, Ph.D., assistant professor in the Molecular and Cellular Oncogenesis Program of the Ellen and Ronald Caplan Cancer Center at The Wistar Institute, has published a new paper in the journal Nature Cancer.

19 Sep 2023

Study assesses duration of protection offered by smallpox infection and possible cross-reaction with Mpox virus

More than 43 years ago, many Chinese residents were vaccinated with the vaccinia virus Tiantan strain (VTT) to protect them from smallpox infection.

19 Sep 2023

Inactivated poliovirus vaccine elicits persistent immunity for up to 10 years

The neutralizing antibodies persistence of the Sabin strain-derived inactivated poliovirus vaccine.

19 Sep 2023

Can your baby's gut bacteria predict food allergies?

Researchers in Italy delve into how changes in gut microbiota during the first 1000 days of life can influence the onset of food allergies in children. The study sheds light on various factors such as birth methods, breastfeeding, and antibiotic use that impact gut health, highlighting the need for more research on effective interventions for allergy prevention.

18 Sep 2023

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

A recent review in the journal Immunity delves into the crucial role of dendritic cells (DCs) in shaping T-cell responses in cancer, highlighting their importance in both priming anti-tumor immunity and in ongoing immune interactions within tumors. The findings underscore the potential of DCs as key targets for next-generation cancer immunotherapies.

18 Sep 2023

Health workers warn loosening mask advice in hospitals would harm patients and providers

Nurses, researchers, and workplace safety officers worry new guidelines from the Centers for Disease Control and Prevention might reduce protection against the coronavirus and other airborne pathogens in hospitals.

18 Sep 2023

How well do current vaccines hold up against new SARS-CoV-2 variants BA.2.86 and FLip?

The study explores the efficacy of three-dose monovalent or bivalent vaccinations in neutralizing newly emerged SARS-CoV-2 variants BA.2.86 and FLip. While BA.2.86 showed lower immune evasion abilities compared to recent XBB variants, it was less effectively neutralized by the monoclonal antibody S309, raising questions about vaccine efficacy against evolving strains.

17 Sep 2023

NIH launches Phase 1 trial of new investigational universal influenza vaccine

Enrollment in a Phase 1 trial of a new investigational universal influenza vaccine candidate has begun at the National Institutes of Health's Clinical Center in Bethesda, Maryland.

15 Sep 2023

Breast milk proteins linked to abundance of beneficial bacteria in infants

More than 320 million years of mammalian evolution has adapted breast milk to meet all the physiological needs of babies: it contains not only nutrients, but also hormones, antimicrobials, digestive enzymes, and growth factors.

15 Sep 2023

Past infections may shape your COVID booster's punch against Omicron

This in-depth study examines how previous immunity impacts the effectiveness of COVID-19 booster vaccinations and susceptibility to Omicron breakthrough infections. The research highlights the significant role of individual immune histories in shaping both humoral and cellular responses to SARS-CoV-2, urging for more tailored vaccine strategies.

14 Sep 2023

Impact of prior SARS-CoV-2 infection and mRNA vaccination on contagiousness and infection risk

The study finds that natural SARS-CoV-2 infection offers stronger immunity against the virus compared to mRNA vaccines. However, mRNA vaccines significantly reduce the infectiousness of individuals with COVID-19, playing a crucial role in limiting the virus's transmission.

14 Sep 2023

UKHSA's flagship SIREN study enters new phase to continue surveillance of respiratory pathogens

The next phase of the study will be known as SIREN 2.0 and began in September 2023.

14 Sep 2023

Eris sublineage EG.5.1 can escape neutralizing antibodies better than other SARS-CoV-2 lineages

As a result of vaccination or infection, our immune system produces antibodies that attach to the spike protein of SARS-CoV-2, preventing the virus from entering and replicating within cells.

14 Sep 2023

New Omicron subvariant BA.2.86: A master of immune escape but not taking over yet

Researchers have isolated a new SARS-CoV-2 Omicron subvariant, BA.2.86, revealing its ability to escape neutralizing antibodies five-fold greater than its ancestor strain. Despite its enhanced immune evasion capabilities, BA.2.86 has not shown a significant difference in spread compared to other current variants.

13 Sep 2023

immunity News and Research

New trial of a preventive HIV vaccine candidate begins in the United States and South Africa

Scientists develop Australia’s first-of-its-kind next-gen mpox diagnostic tool

Vaccine impact: BNT162b2 and pediatric COVID-19 ambulatory visits in kids under 5

Age and underlying conditions increase risk of critical outcomes for hospitalized COVID-19 patients

Tufts Lyme Disease Initiative receives $7M in grants to advance research to next level

High-intensity exercise may reduce colorectal cancer risk in Lynch Syndrome patients

Research demonstrates a double-acting mechanism for fighting triple-negative breast cancer

Study assesses duration of protection offered by smallpox infection and possible cross-reaction with Mpox virus

Inactivated poliovirus vaccine elicits persistent immunity for up to 10 years

Can your baby's gut bacteria predict food allergies?

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

Health workers warn loosening mask advice in hospitals would harm patients and providers

How well do current vaccines hold up against new SARS-CoV-2 variants BA.2.86 and FLip?

NIH launches Phase 1 trial of new investigational universal influenza vaccine

Breast milk proteins linked to abundance of beneficial bacteria in infants

Past infections may shape your COVID booster's punch against Omicron

Impact of prior SARS-CoV-2 infection and mRNA vaccination on contagiousness and infection risk

UKHSA's flagship SIREN study enters new phase to continue surveillance of respiratory pathogens

Eris sublineage EG.5.1 can escape neutralizing antibodies better than other SARS-CoV-2 lineages

New Omicron subvariant BA.2.86: A master of immune escape but not taking over yet

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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