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Pre-clinical data on Novogen’s Cantrixil to be presented at two upcoming conferences

Novogen today announces that Professor Gil Mor MD PhD from Yale Medical School will be presenting pre-clinical data on the lead candidate product, Cantrixil, at two upcoming conferences.

6 Mar 2015

CRISPR-Cas9 gene-editing technology targets every gene in the genome in animal cancer model

For the first time, CRISPR-Cas9 gene-editing technology has been employed in a whole organism model to systematically target every gene in the genome.

6 Mar 2015

Magnetic material may open doors to new strategy for hyperthermia cancer treatment

An extraordinary self-regulating heating effect that can be achieved in a particular type of magnetic material may open the doors to a new strategy for hyperthermia cancer treatment.

5 Mar 2015

Scientists develop nanocarriers for lung cancer treatment

Nanoparticles can function as carriers for medicines to combat lung cancer: Working in a joint project at the NIM (Nanosystems Initiative Munich) Excellence Cluster, scientists from the Helmholtz Zentrum München and the Ludwig-Maximilians-Universität in Munich have developed nanocarriers that site-selectively release medicines/drugs at the tumor site in human and mouse lungs.

5 Mar 2015

Northwestern scientists map brain circuit that processes temperature information

Innately, we pull our hand away when we touch a hot pan on the stove, but little is known about how our brain processes temperature information. Northwestern University scientists now have discovered how a fruit fly's brain represents temperature, mapping it neuron by neuron, which has implications for understanding the much more complex human brain and how it responds to sensory stimuli.

5 Mar 2015

NeuroPerspective features comprehensive reviews of schizophrenia, spinal cord injury

NI Research has released the March/April issue of NeuroPerspective, which features comprehensive reviews of two major areas: Schizophrenia and Spinal cord injury.

3 Mar 2015

Milestones in the History of microCT

An interview with Alexander Sasov about the major milestones in the development of microCT over the past 15 years.

From Bruker BioSpin - NMR, EPR and Imaging 2 Mar 2015

FDA approves LILETTA (levonorgestrel-releasing intrauterine system) to prevent pregnancy

Actavis plc, a leading global specialty pharmaceutical company, and Medicines360, a nonprofit women's health pharmaceutical company, today announced the approval of LILETTA (levonorgestrel-releasing intrauterine system) by the U.S. Food and Drug Administration for use by women to prevent pregnancy for up to three years.

27 Feb 2015

Fat cell transplantation benefits systemic sclerosis patients with non-healing digital ulcers

Digital ulcers (DUs) are a frequent, painful, and quality of life altering complication for patients with systemic sclerosis (SSc), a connective tissue disease causing a progressive loss of small blood vessels and resulting changes in organs and tissues. DUs on the fingertips of SSc patients are slow to heal, if they heal at all, as many are unresponsive to any therapies.

26 Feb 2015

Researchers generate mature, functional skeletal muscles using new approach

A team of researchers from Italy, Israel and the United Kingdom has succeeded in generating mature, functional skeletal muscles in mice using a new approach for tissue engineering. The scientists grew a leg muscle starting from engineered cells cultured in a dish to produce a graft.

25 Feb 2015

Rigel, Bristol-Myers Squibb partner to develop, commercialize TGF beta receptor kinase inhibitors

Rigel Pharmaceuticals, Inc. and Bristol-Myers Squibb Company today announced that they have entered into a collaboration agreement for the discovery, development and commercialization of cancer immunotherapies based on Rigel's extensive portfolio of small molecule TGF beta receptor kinase inhibitors.

23 Feb 2015

Researchers demonstrate clinical efficacy of gallopamil in severe asthma patients

A team of Inserm researchers from the Cardio-Thoracic Research Centre of Bordeaux (Inserm/University of Bordeaux and Bordeaux University Hospital) has demonstrated the clinical efficacy of gallopamil in 31 patients with severe asthma. This chronic disease is characterised by remodelling of the bronchi, which exacerbates the obstruction of the airways already seen in "classic" asthma.

20 Feb 2015

Korean scientists produce flexible, stable monolayers of protein-bound gold nanoparticles

Free-standing nanoparticle films are of great interest for technical applications, such as the development of nanoelectronic devices. In the journal Angewandte Chemie, Korean scientists have introduced very flexible and stable monolayers of gold nanoparticles made by a self-assembly process based on protein aggregation. The films were used to coat wafers up to 10 cm in diameter.

20 Feb 2015

Researchers report development of first 3D tissue-engineered system

A team led by researchers at Tufts University School of Engineering and the University of Pavia has reported development of the first three-dimensional tissue system that reproduces the complex structure and physiology of human bone marrow and successfully generates functional human platelets.

19 Feb 2015

Study shows amyloid formation may link type 2 diabetes and Alzheimer disease

The pathological process amyloidosis, in which misfolded proteins (amyloids) form insoluble fibril deposits, occurs in many diseases, including Alzheimer disease (AD) and type 2 diabetes mellitus (T2D).

17 Feb 2015

Study findings could help scientists better design silicon materials to improve chemotherapy drug delivery

A team of Israeli and American researchers have found that silicon nanomaterials used for the localized delivery of chemotherapy drugs behave differently in cancerous tumors than they do in healthy tissues. The findings could help scientists better design such materials to facilitate the controlled and targeted release of the chemotherapy drugs to tumors.

16 Feb 2015

AXT adds TriFoil imaging products to their preclinical imaging portfolio

TriFoils flagship is the Triumph tri-modal imaging system that incorporates PET/SPECT and CT technologies all in a single instrument. It has a bore size of 15cm and an axial view of 30cm making ideal for small animal studies.

From MR Solutions 13 Feb 2015

'Mad Cow' discovery points to possible neuron killing mechanism behind alzheimer’s and parkinson’s diseases

The new study, published recently in the journal Brain, revealed the mechanism of toxicity of a misfolded form of the protein that underlies prion diseases, such as bovine spongiform encephalopathy (“mad cow disease”) and its human equivalent, Creutzfeldt-Jakob disease.

13 Feb 2015

AXT establishes preclinical imaging portfolio with MR solutions product lines

To coincide with the start of Lorne Cancer conference, AXT are proud to announce the commencement of their distributorship with MR SOLUTIONS, a world leader in the development of innovative preclinical imaging solutions

From MR Solutions 11 Feb 2015

New findings could pave way to develop drug therapies for necrosis-related diseases

Strokes, heart attacks and traumatic brain injuries are separate diseases with certain shared pathologies that achieve a common end - cell death and human injury due to hypoxia, or lack of oxygen.

9 Feb 2015

in vivo News and Research

Pre-clinical data on Novogen’s Cantrixil to be presented at two upcoming conferences

CRISPR-Cas9 gene-editing technology targets every gene in the genome in animal cancer model

Magnetic material may open doors to new strategy for hyperthermia cancer treatment

Scientists develop nanocarriers for lung cancer treatment

Northwestern scientists map brain circuit that processes temperature information

NeuroPerspective features comprehensive reviews of schizophrenia, spinal cord injury

Milestones in the History of microCT

FDA approves LILETTA (levonorgestrel-releasing intrauterine system) to prevent pregnancy

Fat cell transplantation benefits systemic sclerosis patients with non-healing digital ulcers

Researchers generate mature, functional skeletal muscles using new approach

Rigel, Bristol-Myers Squibb partner to develop, commercialize TGF beta receptor kinase inhibitors

Researchers demonstrate clinical efficacy of gallopamil in severe asthma patients

Korean scientists produce flexible, stable monolayers of protein-bound gold nanoparticles

Researchers report development of first 3D tissue-engineered system

Study shows amyloid formation may link type 2 diabetes and Alzheimer disease

Study findings could help scientists better design silicon materials to improve chemotherapy drug delivery

AXT adds TriFoil imaging products to their preclinical imaging portfolio

'Mad Cow' discovery points to possible neuron killing mechanism behind alzheimer’s and parkinson’s diseases

AXT establishes preclinical imaging portfolio with MR solutions product lines

New findings could pave way to develop drug therapies for necrosis-related diseases

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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