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Genmab, ADC Therapeutics agree to develop new antibody-drug conjugate product

Genmab A/S and ADC Therapeutics Sarl, announced today an agreement to develop a new antibody-drug conjugate product combining Genmab's HuMax-TAC antibody and ADC Therapeutics' PBD-based warhead and linker technology.

17 Jun 2013

New collaboration to advance cancer immunotherapy research

The Cancer Research Institute, the Ludwig Institute for Cancer Research and Immune Design, a biotech company focused on immune-based therapies for cancer and other human diseases, today announced that they have signed a collaboration agreement to advance cancer immunotherapy research.

13 Jun 2013

Johns Hopkins expert in brain imaging receives 2013 Paul C. Aebersold Award

A Johns Hopkins expert in brain imaging, Dean F. Wong, M.D., Ph.D., has been honored with the prestigious 2013 Paul C. Aebersold Award for his contributions over the past 30 years in applying basic science to the field of nuclear medicine.

11 Jun 2013

Drug used to control Type II diabetes can help repair spinal cords of mice suffering from inherited disease

A drug used to control Type II diabetes can help repair the spinal cords of mice suffering from the inherited disease adrenoleukodystrophy which, untreated, leads eventually to a paralysis, a vegetative state and death.

10 Jun 2013

Research demonstrates need for development of new treatments for regeneration of nerve cells

Researchers at the University of Michigan have evidence that a single gene controls both halves of nerve cells, and their research demonstrates the need to consider that design in the development of new treatments for regeneration of nerve cells.

5 Jun 2013

Study suggests modulation of "enhancer-directed RNAs" can alter gene expression in living cells

In a pair of distinct but complementary papers, researchers at the University of California, San Diego School of Medicine and colleagues illuminate the functional importance of a relatively new class of RNA molecules.

5 Jun 2013

Bioengineers find innovative ways to grow new cartilage from patient's own stem cells

Cartilage injuries are difficult to repair. Current surgical options generally involve taking a piece from another part of the injured joint and patching over the damaged area, but this approach involves damaging healthy cartilage, and a person's cartilage may still deteriorate with age.

5 Jun 2013

Naurex initiates Phase I trial of NRX-1074 in normal volunteers

Naurex Inc., a clinical-stage company developing innovative treatments to address unmet needs in psychiatry and neurology, today announced that it has begun patient dosing in a Phase I trial of its novel, orally active agent NRX-1074.

4 Jun 2013

Researchers solve long-standing mystery behind dormant disseminated breast tumor cells

The long-standing mystery behind dormant disseminated breast tumor cells and what activates them after years and even decades of latency may have been solved. Researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) have identified the microenvironment surrounding microvasculature - the small blood vessels that transport blood within tissues - as a niche where dormant cancer cells reside. When these blood vessels begin to sprout, the new tips produce molecules that transform dormant cancer cells into metastatic tumors.

4 Jun 2013

Nanoparticle-based immunotherapy for cancer

The German Research Foundation has established a new Collaborative Research Center on "Nanodimensional polymer therapeutics for tumor therapy" (CRC 1066) at Johannes Gutenberg University Mainz and the Max Planck Institute for Polymer Research (MPI-P).

1 Jun 2013

IUPUI assistant professor earns NSF CAREER Award for research on the brain

An assistant professor of computer science at Indiana University-Purdue University Indianapolis has earned the prestigious CAREER Award from the National Science Foundation for research to identify the patterns by which neurons develop and connect to form a brain.

29 May 2013

Study examines effectiveness of VRET on agoraphobia, panic disorder

A number of studies have demonstrated the efficacy of virtual reality exposure therapy in specific phobias, but research in  seriously impaired patients with agoraphobia is lacking.

27 May 2013

ElsaLys Biotech announces first round of financing from Transgene and Sofimac Partners

ElsaLys Biotech, which specializes in the development of therapeutic monoclonal antibodies, announces a first round of financing of 2.1M€ from the biopharmaceutical company Transgene and the investment fund Sofimac Partners.

20 May 2013

Innovative X-ray method advances new treatments for genetic diseases

An international team of scientists using a new X-ray method recorded the internal structure and cell movement inside a living frog embryo in greater detail than ever before.

18 May 2013

InVivo Therapeutics to sponsor Working 2 Walk symposium

InVivo Therapeutics Holdings Corp., a developer of groundbreaking technologies for the treatment of spinal cord injuries and other neurotrauma conditions, today announced that the Company is the Title Sponsor of the 8th annual Working 2 Walk Science & Advocacy Symposium taking place September 27-28, 2013 at the Boston Convention & Exhibit Center in Boston, MA.

16 May 2013

Study finds novel delivery method that helps dissolve stroke-causing clots

A new study from the University of Cincinnati has found that, when delivered via ultrasound, the natural enzyme plasmin is more effective at dissolving stroke-causing clots than the standard of care, recombinant tissue plasminogen activator (rt-PA).

16 May 2013

Avian-origin influenza A virus associated with severe lower respiratory tract diseases

A novel avian-origin reassortant influenza A (H7N9) virus emerged in China in February 2013, and is associated with severe lower respiratory tract diseases. To date, more than 100 human cases of infection, including at least 20 deaths, have been reported in China.

15 May 2013

New technique can lead to effective use of nanoparticles as drug delivery system

A Wayne State University researcher has successfully tested a technique that can lead to more effective use of nanoparticles as a drug delivery system.

8 May 2013

Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

Kinase inhibitors are molecules that block the activity of kinases. Kinases are a specific class of enzymes. They are extremely important in signal transduction processes in the human body meaning that they actually regulate most of the physiological processes that take place in the body.

7 May 2013

Study: Surgeons training in robotic surgery learned best when three different teaching methods are used

By developing a new way to compare techniques for teaching robotic surgery, doctors at The Methodist Hospital and the University of Southern California report in an upcoming issue of the British Journal of Urology International that surgeons training in robotic surgery learned best when three different teaching methods were used.

6 May 2013

in vivo News and Research

Genmab, ADC Therapeutics agree to develop new antibody-drug conjugate product

New collaboration to advance cancer immunotherapy research

Johns Hopkins expert in brain imaging receives 2013 Paul C. Aebersold Award

Drug used to control Type II diabetes can help repair spinal cords of mice suffering from inherited disease

Research demonstrates need for development of new treatments for regeneration of nerve cells

Study suggests modulation of "enhancer-directed RNAs" can alter gene expression in living cells

Bioengineers find innovative ways to grow new cartilage from patient's own stem cells

Naurex initiates Phase I trial of NRX-1074 in normal volunteers

Researchers solve long-standing mystery behind dormant disseminated breast tumor cells

Nanoparticle-based immunotherapy for cancer

IUPUI assistant professor earns NSF CAREER Award for research on the brain

Study examines effectiveness of VRET on agoraphobia, panic disorder

ElsaLys Biotech announces first round of financing from Transgene and Sofimac Partners

Innovative X-ray method advances new treatments for genetic diseases

InVivo Therapeutics to sponsor Working 2 Walk symposium

Study finds novel delivery method that helps dissolve stroke-causing clots

Avian-origin influenza A virus associated with severe lower respiratory tract diseases

New technique can lead to effective use of nanoparticles as drug delivery system

Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

Study: Surgeons training in robotic surgery learned best when three different teaching methods are used

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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