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Novel gene therapy approach may treat dysferlinopathies

The challenge of treating patients with genetic disorders in which a single mutated gene is simply too large to be replaced using traditional gene therapy techniques may soon be a thing of the past. A Nationwide Children's Hospital study describes a new gene therapy approach capable of delivering full-length versions of large genes and improving skeletal muscle function. The strategy may hold new hope for treating dysferlinopathies and other muscular dystrophies.

9 Jul 2012

Researchers describe inflammatory mechanism of sunburn

The biological mechanism of sunburn - the reddish, painful, protective immune response from ultraviolet (UV) radiation - is a consequence of RNA damage to skin cells, report researchers at the University of California, San Diego School of Medicine and elsewhere in the July 8, 2012 Advance Online Publication of Nature Medicine.

9 Jul 2012

Folic acid ‘may benefit diabetics’

Folic acid supplementation can significantly reduce homocysteine levels and may therefore offer an approach for lowering cardiovascular risk among patients with Type 2 diabetes, report researchers.

2 Jul 2012

Study illustrates novel mechanical transduction properties of hematopoietic stem cells

A recent study led by Andrew Puca, Ph.D. under the supervision and direction of Antonio Giordano, M.D., Ph.D. set out to illustrate novel mechanical transduction properties of Hematopoietic Stem Cells in relation to defining the expression of humoral factors by facilitating paracrine/autocrine signalling via microgravity.

2 Jul 2012

Passive smoking risks children’s distance vision

Passive smoke exposure could lead to long-sightedness in children, show Egyptian study results.

29 Jun 2012

New type of micromachine can penetrate tissue and overcome cellular barriers

Microscopically small submarines that can swim through our blood to clear out clogged arteries or destroy malignant tumors. This concept may sound utopian, but it isn’t. Various micro- and nanomachines have in fact already been developed.

27 Jun 2012

Glaukos receives FDA approval for iStent Trabecular Micro-Bypass Stent System

Today, the iStent Trabecular Micro-Bypass Stent System, Model GTS100R/L, was approved by the U.S. Food and Drug Administration. This is the first device approved for use in combination with cataract surgery to reduce pressure inside the eye (intraocular pressure) in adult patients with mild or moderate open-angle glaucoma and a cataract who are currently being treated with medication to reduce intraocular pressure.

26 Jun 2012

Standard aspirin dose may not protect diabetics against blood clots

Many patients with type 2 diabetes may be aspirin resistant. That means the standard aspirin dose may not protect them against blood clots that cause heart attacks and strokes among diabetics, a new clinical study finds. The results will be presented Sunday at The Endocrine Society's 94th Annual Meeting in Houston.

25 Jun 2012

Connexin 43 deficiency may protect against bed rest-associated bone loss

Mice lacking connexin 43, the most abundant gap junction protein in bone, have a decreased susceptibility to the effects of mechanical unloading on bone, US researchers report.

21 Jun 2012

Even small-stage oral SCC metastases impact prognosis

The presence of even small tumor-cell deposits in the lymph nodes of patients with early oral and oropharyngeal squamous cell carcinoma reflects a potential for the primary tumor to metastasize, report researchers in Head and Neck.

21 Jun 2012

MAQUET's INTERGARD SYNERGY vascular graft receives CE mark

MAQUET Cardiovascular, LLC announced today that it has received CE mark for its INTERGARD SYNERGY vascular graft. This graft represents the next generation in antimicrobial grafts combining the well-known antimicrobial properties of silver acetate and triclosan.

19 Jun 2012

DBV Technologies’ Viaskin safe and effective in treating children with peanut allergy

DBV Technologies, creator of Viaskin, a new standard in the treatment of allergy, announced today that AP-HP (Assistance Public - Hôpitaux de Paris) sponsor of the ARACHILD study presented at the EAACI Congress a late breaking oral presentation on safety and efficacy data after six months of epicutaneous immunotherapy in peanut allergy using Viaskin Peanut.

18 Jun 2012

Sanovas receives U.S. patent allowance for microsurgical lung cancer technology

Sanovas, Inc., a medical technology company focused on developing and commercializing next-generation micro-invasive diagnostics, devices and drug delivery technologies, today announced that it has received a Notice of Allowance from the United States Patent and Trademark Office for its first patent relating to systems and methods for the removal of unwanted biological material, such as tissue growths and tumors, in hard-to-reach bodily cavities.

15 Jun 2012

Under ACA 90% of Californians below age of 65 will be enrolled in health insurance programs

Nine out of 10 Californians under the age of 65 will be enrolled in health insurance programs as a result of the Patient Protection and Affordable Care Act (ACA), according to a joint study by the UC Berkeley Center for Labor Research and Education and the UCLA Center for Health Policy Research.

15 Jun 2012

First Edition: June 14, 2012

Today's headlines include reports about how the pending Supreme Court decision is being viewed by investors, and the latest from the campaign trail.

14 Jun 2012

Inovio to participate at Marcum Microcap Conference, BIO International Convention

Inovio Pharmaceuticals, Inc. announced today that Dr. Niranjan Sardesai, COO, will participate on a panel of senior vaccine experts at the 2012 BIO International Convention,the largest global event for the biotechnology industry. Dr. J. Joseph Kim, President and CEO, will present an overview of the company at the Marcum Microcap Conference, which is designed for investors interested in micro-cap companies.

14 Jun 2012

New microfluidic device can sort cancer cells, particles

In life, we sort soiled laundry from clean; ripe fruit from rotten. Two Johns Hopkins engineers say they have found an easy way to use gravity or simple forces to similarly sort microscopic particles and bits of biological matter -- including circulating tumor cells.

13 Jun 2012

Scientists image structure of bacterium protein coat

Bacteria are omnipresent - in the water, the air and the soil, as well as in plants, animals and even people. We tend to think of bacteria as pathogenic, causing disease. We associate them with intestinal upsets and throat infections, pneumonia and blood poisoning.

11 Jun 2012

BCSI launches 5 new cyclotrons for isotope research and production

Best Cyclotron Systems is unveiling five new cyclotrons for isotope research and production at the Society of Nuclear Medicine (SNM) Annual Meeting on June 9-12 in Miami Beach, Florida.

11 Jun 2012

VisionCare expands CentraSight telescope implant provider teams

VisionCare Ophthalmic Technologies, Inc., developer of the first FDA-approved ophthalmic telescope implant indicated to improve vision in patients with end-stage age-related macular degeneration (AMD), announced today the expansion of its CentraSight™ provider teams nationwide.

8 Jun 2012