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Silence strengthens RNAi IP portfolio with issuance of key patent in structural modification technology

Silence Therapeutics plc announces the issuance of United States patent 7,750,144, titled Methods and Compositions for Enhancing Efficacy and Specificity of RNA Silencing, by the United States Patent and Trademark Office (USPTO). The issued patent generally claims methods of producing double stranded (RNAi) agents having decreased off-target silencing activity through certain structural modifications. The ability to minimize the off-target effects of RNAi therapeutics is critical for controlling unwanted cellular activity and/or potential safety concerns.

8 Jul 2010

Aquapharm Biodiscovery signs research agreement with AMRI

Aquapharm Biodiscovery, a leading marine biotechnology company, announced today it has signed a research agreement with Albany Molecular Research to identify novel drug-like compounds and scaffolds with anti-microbial and anti-inflammatory activity from Aquapharm's marine natural products library derived from its extensive collection of marine micro-organisms.

7 Jul 2010

Retin-A Micro Pump combines tretinoin for treating acne: Study

From the minute they wake until the minute they sleep, today's teenagers have busy, demanding schedules. Life may be hectic, but an acne care routine doesn't have to get in the way, according to a new study published in the July 2010 issue of Journal of Drugs in Dermatology.

7 Jul 2010

Novel molecular pathway that regulates invasive growth, metastasis in ER-positive breast cancer discovered

A multi-disciplinary team of international researchers from Ghent University in Belgium, National Human Genome Research Institute (NHGRI) in the US, Imperial College London in the United Kingdom, and INSERM in France have uncovered a novel molecular pathway that regulates invasive growth and metastasis in estrogen receptor-positive breast cancer.

6 Jul 2010

TAP announces sale of first advanced micro bioreactor system

The Automation Partnership (TAP), a world leader in the design and development of innovative automation for life science applications, today announced it has sold its first advanced micro bioreactor system (ambr™) system to a global antibody therapeutics company, where ambr is being used to help predict how antibody expressing cell lines will behave in large scale bioreactors.

30 Jun 2010

ERC awards VIB-K.U.Leuven scientists 3 million euros in research grants

VIB landed two research grants worth 1.5 million euros each. The prestigious grants are courtesy of the European Research Council (ERC) and are aimed at giving talented young scientists the opportunity to develop their own research team. The honor fell to Adrian Liston and Patrik Verstreken, both recently transferred to VIB-K.U.Leuven from abroad.

30 Jun 2010

Herniated disk can cause low back and leg pain in adults

A literature review, led by Dr. Joseph Lee, published in the June 2010 issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS) suggests that a herniated disk is one of the most frequent causes of low back and leg pain in adults, but surgery is not for everyone. Between 60 and 80 percent of people will experience low back pain at some point in their lives.

30 Jun 2010

Literature review discusses herniated disks and treatment options for low back pain

29 Jun 2010

Scientists use PGS method to analyse chromosomal status of eggs

The efficacy of preimplantation genetic screening has been one of the most hotly disputed subjects in assisted reproduction over the past few years. The European Society of Human Reproduction and Embryology PGS Task Force has now shown, in its groundbreaking proof of principle study, that screening of polar bodies (small cells that are the by-product of egg development), is a reliable method to analyse the chromosomal status of an egg.

28 Jun 2010

EVISTA improves bone quality as measured by HRpQCT: IIT

Interim data from a prospective Investigator Initiated Trial presented today at the ECTS, the 37th European Symposium on Calcified Tissues, in Glasgow, demonstrates that EVISTA (raloxifene 60mg; once-daily, distributed in 34 countries by DAIICHI SANKYO), indicated for the treatment and prevention of osteoporosis in postmenopausal women, improves bone quality as measured by the high-resolution peripheral quantitative computed tomography.

28 Jun 2010

Increasing the amount of preservatives may reduce food poisoning

In response to consumer demand for more natural food, the food industry has reduced the amount of preservatives in food over recent years. A common preservative is acetic acid, which is used to stop bacterial growth in dressings, sauces, cheese and pickles.

25 Jun 2010

Zilog launches ZMOTION Detection and Control solutions

Zilog, an IXYS company, and a trusted supplier of application specific, embedded micro controller (MCU) system-on-chip (SoC) solutions for industrial and consumer markets, today introduced its latest sensing and control technology for motion detection applications, including intrusion, security alarm industry, customer sensing and lighting control, medical patient monitoring, and other energy management applications.

24 Jun 2010

Debiotech, STMicroelectronics to showcase novel insulin "Jewel Pump" at ADA Congress

Debiotech and STMicroelectronics today announced that they will publicly showcase their novel insulin "Jewel Pump" at the Debiotech stand at the American Diabetes Association 70th Scientific Sessions (June 25-29) in Orlando, Florida.

24 Jun 2010

SPS receives $2.2M NHLBI grant to commercialize steerable cardiac mapping, ablation catheter technology

Strategic Polymer Sciences, Inc. (SPS), an innovator in advanced medical devices based on its proprietary electroactive polymer (EAP) technology, today announced it has received a $2.2 million grant from the National Heart, Lung and Blood Institute (NHLBI) of the National Institutes of Health (NIH). The SPS grant is one of only ten awarded nationwide by the NIH under a Recovery Act Limited Competition called The Biomedical Research, Development, and Growth to Spur the Acceleration of New Technologies (BRDG-SPAN) Pilot Program.

23 Jun 2010

World's first invisible-in-the-canal hearing aid launched

Starkey Laboratories, Inc., one of the world's leading hearing technology companies, is excited to introduce the S Series™ iQ OtoLens™, the world's first invisible-in-the-canal (IIC) hearing aid. OtoLens, a custom-molded hearing aid built using Starkey's Comfort Fit process, lives in the second bend of the ear, meaning that it is truly 100 percent invisible.

22 Jun 2010

Simulations Plus third-quarter consolidated preliminary revenues up 14.9% to $3.1M

Simulations Plus, Inc., a leading provider of software for pharmaceutical discovery and development, today released preliminary revenues for its third fiscal quarter ended May 31, 2010.

21 Jun 2010

Antibacterial lab coats to help prevent spread of disease in hospitals

According to the Centers for Disease Control and Prevention, 99,000 people die every year from infections acquired while in hospitals. "The goal in our profession is to help cure you not introduce you to another deadly infection," said Dr. Charles Kinder, Heart Rhythm expert and Director of Heart Rhythm Program at Heart Care Centers of Illinois.

21 Jun 2010

New Brunswick Scientific, Pall partner to develop new disposable bioreactor systems

New Brunswick Scientific, an Eppendorf Company, and Pall Corporation today announced a joint product development and marketing agreement to create and supply new disposable bioreactor systems.

From Pall Corporation 14 Jun 2010

'Micro-ear' to screen for malaria, sleeping sickness

A team of researchers from the Universities of Glasgow and Oxford, and the UK's National Institute of Medical Research at Mill Hill, are developing a 'micro-ear' which may help develop medicines and screening for diseases such as malaria and sleeping sickness in Africa. The project is in two parts, explains Professor Jon Cooper, a bio-engineer at University of Glasgow.

14 Jun 2010

USPTO issues patent covering methods for enhancing RNA silencing activity of RNAi agents

Silence Therapeutics plc announces the issuance of United States patent 7,732,593, titled Methods and Compositions For Controlling Efficacy of RNA Silencing, by the United States Patent and Trademark Office. The issued patent, which is based on the seminal research of Phillip D. Zamore, Ph.D., Howard Hughes Medical Institute Investigator, the Gretchen Stone Cook Chair of Biomedical Sciences, and Professor of Biochemistry & Molecular Pharmacology at University of Massachusetts Medical School, generally claims methods of enhancing the RNA silencing activity of RNA interference (RNAi) agents through certain structural modifications.

14 Jun 2010

micro News and Research

Silence strengthens RNAi IP portfolio with issuance of key patent in structural modification technology

Aquapharm Biodiscovery signs research agreement with AMRI

Retin-A Micro Pump combines tretinoin for treating acne: Study

Novel molecular pathway that regulates invasive growth, metastasis in ER-positive breast cancer discovered

TAP announces sale of first advanced micro bioreactor system

ERC awards VIB-K.U.Leuven scientists 3 million euros in research grants

Herniated disk can cause low back and leg pain in adults

Literature review discusses herniated disks and treatment options for low back pain

Scientists use PGS method to analyse chromosomal status of eggs

EVISTA improves bone quality as measured by HRpQCT: IIT

Increasing the amount of preservatives may reduce food poisoning

Zilog launches ZMOTION Detection and Control solutions

Debiotech, STMicroelectronics to showcase novel insulin "Jewel Pump" at ADA Congress

SPS receives $2.2M NHLBI grant to commercialize steerable cardiac mapping, ablation catheter technology

World's first invisible-in-the-canal hearing aid launched

Simulations Plus third-quarter consolidated preliminary revenues up 14.9% to $3.1M

Antibacterial lab coats to help prevent spread of disease in hospitals

New Brunswick Scientific, Pall partner to develop new disposable bioreactor systems

'Micro-ear' to screen for malaria, sleeping sickness

USPTO issues patent covering methods for enhancing RNA silencing activity of RNAi agents

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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