Microcephaly News and Research

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Measuring head circumference (also known as occipito-frontal circumference) is a significant part of the proper evaluation of a child’s growth and development, as it represents a direct indication of head growth. Therefore deviations from normal head growth may reveal certain congenital or acquired problem.

Does COVID-19 injure the placenta of pregnant women?

News-Medical speaks to Dr. Jeffery Goldstein about whether COVID-19 is damaging the placentas of pregnant women and what women can do to protect themselves.

12 Jun 2020

COVID-19 may damage the central nervous system

Researchers at University Hospital Düsseldorf, Germany, have provided important insights into the potential impact that coronavirus disease 2019 (COVID-19) could have on the central nervous system.

21 May 2020

Researchers highlight the need to revise the protocol for detecting ZIKV infection in placenta

Shortly after the explosion in microcephaly cases caused by Zika virus in Brazil in 2015-16, several scientific studies were published with evidence that the pathogen is capable of crossing the human placenta, the organ that keeps the fetus connected to the mother's body during pregnancy.

20 May 2020

Scientists model human CMV-induced microcephaly using brain organoids

A City of Hope scientist is one step closer to discovering what weakens a pathogen that appears to cause babies to be born with abnormally small heads.

30 Mar 2020

Researchers probe how specific genes can impact early brain development

When brains begin developing, there are a lot of moving parts -- and when mutations happen in early neurodevelopment, it can lead to disorders like macrocephaly and autism.

11 Mar 2020

Researchers uncover why Zika virus caused most harmful brain damage to Brazilian newborns

Due to Zika virus, more than 1,600 babies were born in Brazil with microcephaly, or abnormally small heads, from September 2015 through April 2016.

18 Feb 2020

New study describes inflammatory reaction in lab-developed human astrocytes

Astrocytes are neural cells with many important functions in the nervous system. The inflammation of these cells occurs in brain infections and neurodegenerative disorders, a process called astrogliosis.

14 Feb 2020

Experimental vaccine could be effective against both Zika and Dengue

Walter Reed army institute of research has shown that a new vaccine against the Zika virus could be effective against both Zika and dengue virus. The study titled, “Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue experienced donor,” in the latest issue of the journal Nature Medicine.

3 Feb 2020

Scientists reveal the damaging effect of Zika virus on a type of brain cell

The Zika virus (ZIKV) outbreak in Brazil in 2015 sparked for many health agencies and scientists to study the pathogen, which has been linked to microcephaly and other fetal neurological disorders collectively known as Congenital Zika Syndrome.

27 Jan 2020

Research unravels consequences of Zika virus attack on neural cells

Previous studies regarding the damage of the Zika virus on the brain had already pointed out the virus's predilection for a certain neural cell: the astrocyte. However, few studies have proposed to identify the infection effects on these cells, as well as their association with developmental alterations, including brain malformations and microcephaly.

27 Jan 2020

Brain parasite makes rodents unafraid of cats, other predators

Cats have the power to control the minds of rodents, through a brain parasite called Toxoplasma gondii. The pathogen exerts a strange mind control on rodents that make them lose their fear of cats and become easier to catch.

15 Jan 2020

Poor diet among infants' mothers linked to rise in Congenital Zika Syndrome cases

Congenital Zika Syndrome (CZS) refers to a collection of developmental malformations associated with Zika virus (ZIKV) congenital infection.

12 Jan 2020

Zika virus can affect infants despite ‘normal’ testing at birth

A study reports that infants born to Zika-exposed mothers showed neurodevelopmental slowing despite testing as normal at birth.

7 Jan 2020

Study underscores the importance of long-term follow-up for Zika-exposed infants

Colombian infants exposed to Zika virus in the womb showed neurodevelopmental delays as toddlers, despite having "normal" brain imaging and head circumference at birth, a finding that underscores the importance of long-term neurodevelopmental follow-up for Zika-exposed infants, according to a study published online Jan. 6, 2020, in JAMA Pediatrics.

6 Jan 2020

Scientists unveil how Zika virus replicates

The World Health Organization (WHO) declared the Zika virus infection a global threat during the peak of its outbreak in 2016. Since then, scientists and health experts raced to understand the virus better to develop novel and effective vaccines and treatments for the disease. Now, a team of researchers in China revealed how a protein in the virus reshapes its host to boost viral replication.

23 Dec 2019

Researchers make significant advances in developing novel Zika virus vaccine

Researchers from the University of Adelaide have made significant advances in developing a novel vaccine against Zika virus, which could potentially lead to global elimination of the disease.

14 Dec 2019

Eating disorder can affect pregnancy outcome and offspring’s health

A pregnant woman with an eating disorder needs to be screened for complications more carefully because she is high-risk.

21 Nov 2019

Eating disorders increase risk of premature birth

Pregnant women with eating disorders should undergo extended pregnancy screenings considering their increased risk of complications. That is the conclusion from a study by researchers at Karolinska Institutet in Sweden published in the journal JAMA Psychiatry.

20 Nov 2019

Children born to women on HIV therapy more likely to have microcephaly, developmental delays

Children born to women on HIV therapy containing the drug efavirenz were 2 to 2.5 times more likely to have microcephaly, or small head size, compared to children born to women on regimens of other antiretroviral drugs, according to an analysis funded by the National Institutes of Health.

18 Nov 2019

Study provides new insights into potential outcomes of Zika virus infection

Using a relevant animal model (pigs), University of Saskatchewan researchers have shown that mild Zika virus infection in fetuses can cause abnormal brain development in apparently healthy young animals.

15 Nov 2019