neoplasia News and Research

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Advaxis files investigational new drug application for Lovaxin C

Advaxis Inc. completed its filing of a new investigational new drug ("IND") application with the U.S. Food and Drug Administration ("FDA"). This filing follows the successful completion of a Phase I study overseas.

20 May 2008

Biomarker predicts malignancy potential of HG-PIN lesions in the prostate

Men whose prostate cancer screenings show high grade prostatic intraepithelial neoplasia (HG-PIN) may find themselves in limbo, "stuck" between diagnoses - they are told prostate cancer has not yet developed, but it might, and they are advised to undergo repeated needle biopsies as a precaution.

1 May 2008

New imaging technique provides better view of Barrett's esophagus

Novel techniques to improve the quality of imaging are helping doctors get a better look at esophageal conditions such as Barrett's esophagus (BE), but they do not necessarily improve the diagnosis or physician agreement on images, according to a study published this month in Gastroenterology , the official journal of the American Gastroenterological Association (AGA) Institute.

12 Mar 2008

Colorectal cancer gene found

Case Western Reserve University School of Medicine researchers published a study in the March 7th issue of The American Journal of Human Genetics identifying the hereditary components of colorectal cancer (CRC.)

10 Mar 2008

Acanthus ilicifolius plant may combat liver cancer

Liver cancer is the fifth most common cancer in the world with a poor prognosis. About three quarters of the cases of liver cancer are found in Southeast Asia, including China, Hong Kong, Taiwan, Korea, India, and Japan.

17 Jan 2008

Oncolytics Biotech issued new U.S. patent - reovirus for the treatment of neoplasia

Oncolytics Biotech Inc. has announced that it has been granted U.S. Patent 7,300,650 entitled "Reovirus for the Treatment of Neoplasia."

27 Nov 2007

Pre-malignant mammary lesions in dogs and humans display many of the same characteristics

...a discovery that could lead to better understanding of breast cancer progression and prevention for people and pets, said a Purdue University scientist from the School of Veterinary Medicine.

16 Nov 2007

Knowing risk can determine what kind of colon cancer screening is best

While colonoscopy has become widely used for colorectal cancer screening, nearly two-thirds of screening colonoscopies show no cancer or pre-cancerous polyps.

29 Oct 2007

Obesity strongest risk factor for colorectal cancer in women

Research presented at the 72nd Annual Scientific Meeting of the American College of Gastroenterology found that obesity, among other important risk factors, was the strongest risk factor for colorectal cancer in women.

16 Oct 2007

AGA Institute statement on CT colonography study

Colorectal cancer is the second-leading cause of cancer deaths, affecting both men and women nearly equally and is one of the most preventable cancers.

8 Oct 2007

Insights into colorectal cancer screening

Two studies in the October issue of the journal Gastroenterology may help in refining recommendations for the use of colonoscopy to screen for colorectal cancer.

2 Oct 2007

GSK's Cervarix receives positive opinion in Europe

GlaxoSmithKline has announced that its cervical cancer candidate vaccine received a positive opinion from the European Committee for Human Medicinal Products (CHMP) for the prevention of precancerous lesions (high grade cervical intraepithelial neoplasia - CIN grades 2 and 3) and cervical cancer causally related to human papillomavirus types 16 and 18.

19 Jul 2007

Folic acid supplements do not reduce risk of precancerous colon tumors

Taking folic acid supplements does not reduce the risk of developing precancerous tumors in the colon and may even increase the risk, a new study has found.

16 Jun 2007

Folic acid does not decrease the risk of benign colorectal tumors

New research indicates that folic acid supplementation does not decrease the risk of benign colorectal tumors, but may possibly increase the risk for some types of colorectal tumors, according to a study in the June 6 issue of JAMA .

8 Jun 2007

Taking a jab at cancer by stimulating the immune system

As the first FDA-approved cancer vaccine, designed to protect against human papillomavirus, has moved from scientific discussion to social debate, other vaccine studies are continuing to make progress.

18 Apr 2007

Roche and Transgene S.A. partner on HPV vaccine program

Roche and Transgene S.A. have announced that they have entered into an exclusive worldwide collaboration agreement to develop and commercialize products from Transgene's therapeutic vaccine program against Human Papilloma Virus-mediated diseases.

11 Apr 2007

Transgenomic signs contract with OSI Pharmaceuticals for cancer genetic analysis

Transgenomic has announced that it has signed a contract with OSI Pharmaceuticals to complete an analysis of specific cancer pathway genes.

11 Apr 2007

Recognition for cancer researchers

World-class cancer researchers whose science has significantly contributed to progress in the fight against cancer will be recognized April 14-18, 2007, by the American Association for Cancer Research (AACR) at its 2007 Annual Meeting in Los Angeles, Calif.

3 Apr 2007

FDA accepts two Roche diagnostics HPV tests for review

Roche has announced today that the United States (U.S.) Food & Drug Administration has accepted for review its applications for two human papillomavirus (HPV) tests.

From Roche Sequencing and Life Science 6 Mar 2007