p53 Protein News and Research

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The TP53 is a gene that instructs the cell to produce tumor protein (p53) ; a vital transcription factor and tumor suppressor. P53 is known as the “guardian of the genome” as it helps in regulating the cell cycle and acts as a tumor suppressor.
p53 restoration of function drug candidate: an interview with Dr. Wayne Danter, MD, FRCPC President and CEO of Critical Outcome Technologies

p53 restoration of function drug candidate: an interview with Dr. Wayne Danter, MD, FRCPC President and CEO of Critical Outcome Technologies

Tumor suppressor p53 inactivation and restoration: an interview with Dr. Xin Lu, Ludwig Institute for Cancer Research

Tumor suppressor p53 inactivation and restoration: an interview with Dr. Xin Lu, Ludwig Institute for Cancer Research

Study suggests possible way to halt cancer development in premalignant cells

Study suggests possible way to halt cancer development in premalignant cells

Inherited mutations in p53 gene put people at high risk of developing cancers

Inherited mutations in p53 gene put people at high risk of developing cancers

Mechanism of tumor suppressor p53 inactivation described

Mechanism of tumor suppressor p53 inactivation described

Researchers identify new mechanism in onset of motor neuron diseases

Researchers identify new mechanism in onset of motor neuron diseases

TP63 gene correlates significantly with worse prognosis of melanoma

TP63 gene correlates significantly with worse prognosis of melanoma

Scientists identify specific p53 pocket that can be targeted by cancer-fighting drugs

Scientists identify specific p53 pocket that can be targeted by cancer-fighting drugs

p53 activation suppresses malic enzyme expression and leads to senescence in pre-cancerous cells

p53 activation suppresses malic enzyme expression and leads to senescence in pre-cancerous cells

Study on effect of glucose on cancer growth in mice

Study on effect of glucose on cancer growth in mice

Researchers discover genetics secrets of ovarian cancer tumors

Researchers discover genetics secrets of ovarian cancer tumors

PHF20 transcriptional factor plays a unique role in regulating p53

PHF20 transcriptional factor plays a unique role in regulating p53

New role for oncogenic signaling pathway in embryonic stem cell self-renewal

New role for oncogenic signaling pathway in embryonic stem cell self-renewal

Researchers unlock genetic secrets of peripheral T-cell lymphomas

Researchers unlock genetic secrets of peripheral T-cell lymphomas

Researchers discover mechanism that favours disappearance and inhibition of SCC development

Researchers discover mechanism that favours disappearance and inhibition of SCC development

p53 protein may show a typical prion-like behavior when mutated

p53 protein may show a typical prion-like behavior when mutated

Do we age as a consequence of being protected against cancer?

Do we age as a consequence of being protected against cancer?

Researchers discover two effective cancer killers

Researchers discover two effective cancer killers

AICR recommends intake of cancer-fighting foods

AICR recommends intake of cancer-fighting foods

Cylene advances preclinical development of CX-5461 for treatment of cancer

Cylene advances preclinical development of CX-5461 for treatment of cancer