p53 Protein News and Research

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The TP53 is a gene that instructs the cell to produce tumor protein (p53) ; a vital transcription factor and tumor suppressor. P53 is known as the “guardian of the genome” as it helps in regulating the cell cycle and acts as a tumor suppressor.
Scientists explain mechanism behind acute myeloid leukemia

Scientists explain mechanism behind acute myeloid leukemia

Study demonstrates p53 protein becomes activated during gamete formation

Study demonstrates p53 protein becomes activated during gamete formation

Study identifies mechanism that interrupts normal p53 gene function leading to tumor development

Study identifies mechanism that interrupts normal p53 gene function leading to tumor development

Ascenta Therapeutics, sanofi-aventis sign global licensing agreement for cancer drug candidates

Ascenta Therapeutics, sanofi-aventis sign global licensing agreement for cancer drug candidates

New p53 knockout rat model improves timelines for carcinogenicity screening

New p53 knockout rat model improves timelines for carcinogenicity screening

Gene defect promotes aggressive forms of ovarian cancer

Gene defect promotes aggressive forms of ovarian cancer

Brain stem cells in subventricular zone characterized by transcription factor Protein Tlx

Brain stem cells in subventricular zone characterized by transcription factor Protein Tlx

Roche Molecular Systems, Merck Sharp & Dohme announce cancer therapeutics collaboration

Roche Molecular Systems, Merck Sharp & Dohme announce cancer therapeutics collaboration

Cancer Research UK scientists named on New Year's Honours list

Cancer Research UK scientists named on New Year's Honours list

Champions Biotechnology and Ramot establish licensing agreement

Champions Biotechnology and Ramot establish licensing agreement

Activating TAp63 protein, a viable anti-cancer strategy

Activating TAp63 protein, a viable anti-cancer strategy

Champions Biotechnology obtains global rights to Tel Aviv University's TAR-1 compound

Champions Biotechnology obtains global rights to Tel Aviv University's TAR-1 compound

Estrogen can reduce stroke damage by inactivating a tumor-suppressing protein

Estrogen can reduce stroke damage by inactivating a tumor-suppressing protein

Dramatic drop in deaths from most common cancers

Dramatic drop in deaths from most common cancers

Discovery of potent metastasis inhibitor

Discovery of potent metastasis inhibitor

Study gives clues to how ultra-rare adrenocortical cancer forms

Study gives clues to how ultra-rare adrenocortical cancer forms

Glioblastoma may originate in neural stem cells

Glioblastoma may originate in neural stem cells

Nanoparticle delivery of a fully functioning copy of P53 tumor suppressor gene

Nanoparticle delivery of a fully functioning copy of P53 tumor suppressor gene

Chemopreventive isothiocyanates selectively depletes mutant p53 in tumor cells

Chemopreventive isothiocyanates selectively depletes mutant p53 in tumor cells

Research shows how p53 mutations link to high-grade breast cancer, poor outcomes

Research shows how p53 mutations link to high-grade breast cancer, poor outcomes