siRNA News and Research

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Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA molecules, 20-25 nucleotides in length, that play a variety of roles in biology. Most notably, siRNA is involved in the RNA interference (RNAi) pathway, where it interferes with the expression of a specific gene. In addition to their role in the RNAi pathway, siRNAs also act in RNAi-related pathways, e.g., as an antiviral mechanism or in shaping the chromatin structure of a genome; the complexity of these pathways is only now being elucidated.
siRNA delivery into human T cells and primary cells with carbon-nanotube transporters

siRNA delivery into human T cells and primary cells with carbon-nanotube transporters

siRNA delivery into human T cells and primary cells with carbon-nanotube transporters

siRNA delivery into human T cells and primary cells with carbon-nanotube transporters

Nanoparticles yield delivery tools for therapeutic nucleic acids

Nanoparticles yield delivery tools for therapeutic nucleic acids

Renegade ribonucleic acid

Renegade ribonucleic acid

Co-delivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer

Co-delivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer

BRIT1 gene plays a pivotal role in DNA damage detection and repair

BRIT1 gene plays a pivotal role in DNA damage detection and repair

Objections to Kreutzer-Limmer patent by Sirna Therapeutics accepted by the European Patent Office

Objections to Kreutzer-Limmer patent by Sirna Therapeutics accepted by the European Patent Office

Scientists use "small interfering RNAs" to block the spread of human colorectal cancer cells

Scientists use "small interfering RNAs" to block the spread of human colorectal cancer cells

Effective gene suppression using small interfering RNA in hard-to-transfect human T cells

Effective gene suppression using small interfering RNA in hard-to-transfect human T cells

Genetics of human muscular dystrophy

Genetics of human muscular dystrophy

Sirna Therapeutics awarded patent covering large-scale synthesis of RNAi-based therapeutics

Sirna Therapeutics awarded patent covering large-scale synthesis of RNAi-based therapeutics

Cells have developed a surprising transportation system for their endosomes

Cells have developed a surprising transportation system for their endosomes

Scientists reverse memory loss in mice with Alzheimer's

Scientists reverse memory loss in mice with Alzheimer's

RNAi therapeutic successful for treatment of SARS respiratory virus in Rhesus Macaque

RNAi therapeutic successful for treatment of SARS respiratory virus in Rhesus Macaque

A systematic search through human genes

A systematic search through human genes

Sirna Therapeutics granted new UK patents

Sirna Therapeutics granted new UK patents

Human cells can silence an essential part of HIV's genetic make-up

Human cells can silence an essential part of HIV's genetic make-up

A new approach to prevent cancer

A new approach to prevent cancer

Groundbreaking results for the potential treatment of Huntington's Disease

Groundbreaking results for the potential treatment of Huntington's Disease

Study suggests combination therapy could stop spread, halt growth of melanomas

Study suggests combination therapy could stop spread, halt growth of melanomas