siRNA News and Research

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Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA molecules, 20-25 nucleotides in length, that play a variety of roles in biology. Most notably, siRNA is involved in the RNA interference (RNAi) pathway, where it interferes with the expression of a specific gene. In addition to their role in the RNAi pathway, siRNAs also act in RNAi-related pathways, e.g., as an antiviral mechanism or in shaping the chromatin structure of a genome; the complexity of these pathways is only now being elucidated.
IDT webinar explores effective RNAi and antisense oligo methods

IDT webinar explores effective RNAi and antisense oligo methods

Researchers use advanced photodynamic therapy to combat ovarian cancer in laboratory animals

Researchers use advanced photodynamic therapy to combat ovarian cancer in laboratory animals

Scientists reveal potential therapeutic approach to idiopathic pulmonary fibrosis

Scientists reveal potential therapeutic approach to idiopathic pulmonary fibrosis

Trends, R&D progress, and predicted revenues in RNAi therapies

Trends, R&D progress, and predicted revenues in RNAi therapies

University of Leeds scientists uncover genes implicated in common inherited diseases

University of Leeds scientists uncover genes implicated in common inherited diseases

RXi Pharmaceuticals receives Notice of Allowance from USPTO for novel, self-delivering RNAi platform

RXi Pharmaceuticals receives Notice of Allowance from USPTO for novel, self-delivering RNAi platform

Alnylam files clinical trial application for alpha-1 liver disease, presents data at DDW

Alnylam files clinical trial application for alpha-1 liver disease, presents data at DDW

Non-coding RNAs in maternal food can pass through placenta to regulate fetal gene expression

Non-coding RNAs in maternal food can pass through placenta to regulate fetal gene expression

Case Western Reserve researchers find potential game-changer for triple-negative breast cancer

Case Western Reserve researchers find potential game-changer for triple-negative breast cancer

Scientists develop nanoneedle technique to generate new blood vessels

Scientists develop nanoneedle technique to generate new blood vessels

Experimental nanoparticle therapy speeds healing of all sorts of wounds

Experimental nanoparticle therapy speeds healing of all sorts of wounds

MTfp-­siRNA reduces blood vessel infarct, improves overall brain activity in ischemic stroke model

MTfp-­siRNA reduces blood vessel infarct, improves overall brain activity in ischemic stroke model

NIAID partners with Liberian government to test ZMapp drug for Ebola virus disease

NIAID partners with Liberian government to test ZMapp drug for Ebola virus disease

Researchers reveal new understanding of pathobiology behind vestibular schwannoma

Researchers reveal new understanding of pathobiology behind vestibular schwannoma

RXi closes exclusive global license agreement with Hapten Pharmaceuticals for Samcyprone

RXi closes exclusive global license agreement with Hapten Pharmaceuticals for Samcyprone

Dartmouth scientists discover novel cancer resistance mechanism

Dartmouth scientists discover novel cancer resistance mechanism

Changes in current Ebola virus epidemic could potentially interfere with experimental treatments

Changes in current Ebola virus epidemic could potentially interfere with experimental treatments

Precision NanoSystems, Arcturus Therapeutics partner to develop RNA medicines

Precision NanoSystems, Arcturus Therapeutics partner to develop RNA medicines

Arcturus to exhibit new mRNA therapeutics pipeline at two healthcare conferences

Arcturus to exhibit new mRNA therapeutics pipeline at two healthcare conferences

Sirnaomics submits STP705 IND Application to CFDA for skin scar treatment

Sirnaomics submits STP705 IND Application to CFDA for skin scar treatment