Therapeutics News and Research

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Study reveals crucial insights into the ocular effects of Zika virus infection during pregnancy

A groundbreaking study published in the journal iScience presents crucial insights into the ocular effects of Zika virus infection during pregnancy and offers promising avenues for therapeutic intervention.

28 Mar 2024

Unraveling gene regulation's role in pulmonary fibrosis

Regulators of gene expression are thought to play an outsized role in disorders from cancers to heart disease. But how exactly do variations in gene regulation translate into a disease's biology?

28 Mar 2024

Xenotransplantation model used for studying microglial response to Alzheimer's disease

Microglia are specialized immune cells in the brain. While they normally protect our brains, they can also contribute to neurodegenerative diseases such as Alzheimer's.

27 Mar 2024

Breakthrough study offers hope for an effective HIV cure

By 2030, the World Health Organization (WHO), the Global Fund and UNAIDS are hoping to end the human immunodeficiency virus (HIV) and AIDS epidemic.

26 Mar 2024

Teva UK and Closed Loop Medicine announce strategic partnership to advance development of personalised medicines

Teva UK Limited and Closed Loop Medicine Ltd have announced a strategic partnership to advance the development of personalised medicine.

26 Mar 2024

Ubiquigent and Debiopharm enter agreement to support USP1 inhibitor programme for Debio 0432

Project will be a demonstration of how Ubiquigent’s DUB-centric platform can support the development of DUB inhibitors all the way from discovery through to clinical development.

From Ubiquigent Limited 26 Mar 2024

C-Path announces formation of new task force to foster drug development for Progressive Supranuclear Palsy

Critical Path Institute (C-Path) today announced the formation of a new task force under its Rare Disease Cures Accelerator-Data and Analytics Platform, dedicated to advancing therapeutic development for Progressive Supranuclear Palsy.

26 Mar 2024

New glycan found to play a key role in nasal colonization of whooping cough bacteria

Researchers have identified a new complex-carbohydrate biomolecule, or glycan, that plays a key role in the nasal colonization of the Bordetella bacteria responsible for whooping cough.

25 Mar 2024

Common household chemicals may be linked to neurological diseases

A team of researchers from the Case Western Reserve University School of Medicine has provided fresh insight into the dangers some common household chemicals pose to brain health.

25 Mar 2024

New compound shows promise as a more effective treatment for schistosomiasis

A newly developed compound is showing promise in animal studies as a more effective treatment for human schistosomiasis, an understudied tropical disease caused by parasitic worms.

25 Mar 2024

Study reveals ADHD medication reduces psychiatric hospitalizations and work disability

Study highlights the benefits and potential risks of ADHD medication, revealing that stimulants like amphetamines and methylphenidate reduce the risk of psychiatric hospitalization and improve long-term employment outcomes, though concerns about adverse effects such as increased heart rate and potential for triggering psychosis or mania remain.

24 Mar 2024

Study evaluates the use of tirzepatide in overweight/obese adults with type 1 diabetes

A new study in the peer-reviewed journal Diabetes Technology & Therapeutics (DTT) evaluated the use of tirzepatide in overweight/obese adults with type 1 diabetes.

22 Mar 2024

Researchers create new platform to identify proteins for targeted treatment of disease

Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins -; a new but largely unrealized approach to the treatment of disease.

22 Mar 2024

Study shows cellular, molecular overlaps in ALS and FTLD

On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, manifest in very different ways. In addition, they are known to primarily affect very different regions of the brain.

22 Mar 2024

Scientists uncover four proteins that govern the identity of anaplastic large cell lymphoma

A collaboration between scientists from St. Jude Children's Research Hospital and Dana-Farber Cancer Institute uncovered four proteins that govern the identity of anaplastic large cell lymphoma (ALCL), an aggressive form of cancer.

22 Mar 2024

Weill Cornell Medicine receives $1.65 million grant for groundbreaking RNA research

A team led by Dr. Samie Jaffrey, the Greenberg-Starr Professor of Pharmacology at Weill Cornell Medicine, has been awarded a three-year, $1.65 million grant for RNA research under a biotechnology-development program run by the U.S. National Science Foundation.

21 Mar 2024

Study highlights global fertility decline and its implications for the future

The world is approaching a low-fertility future. Although by 2100 more than 97% of countries and territories will have fertility rates below what is necessary to sustain population size over time, comparatively high fertility rates in numerous low-income countries, predominantly in western and eastern sub-Saharan Africa, will continue to drive population increases in these locations throughout the century.

21 Mar 2024

Scientists shed light on key immune regulators involved in Alzheimer’s and other disorders of lipid-rich tissues

Using novel genetic and genomic tools, researchers at the Icahn School of Medicine at Mount Sinai have shed light on the role of immune cells called macrophages in lipid-rich tissues like the brain, advancing our understanding of Alzheimer's and other diseases.

21 Mar 2024

Investigational gene therapy shows promise for rare childhood neurodegenerative disease

An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy (GAN), was well tolerated and showed signs of therapeutic benefit in a clinical trial led by the National Institutes of Health.

20 Mar 2024

Enhancing the safety and efficacy of breast and ovarian cancer treatment

Some anti-cancer treatments not only target tumour cells but also healthy cells. If their effects on the latter are too strong, their use can become limiting.

20 Mar 2024

Therapeutics News and Research

Study reveals crucial insights into the ocular effects of Zika virus infection during pregnancy

Unraveling gene regulation's role in pulmonary fibrosis

Xenotransplantation model used for studying microglial response to Alzheimer's disease

Breakthrough study offers hope for an effective HIV cure

Teva UK and Closed Loop Medicine announce strategic partnership to advance development of personalised medicines

Ubiquigent and Debiopharm enter agreement to support USP1 inhibitor programme for Debio 0432

C-Path announces formation of new task force to foster drug development for Progressive Supranuclear Palsy

New glycan found to play a key role in nasal colonization of whooping cough bacteria

Common household chemicals may be linked to neurological diseases

New compound shows promise as a more effective treatment for schistosomiasis

Study reveals ADHD medication reduces psychiatric hospitalizations and work disability

Study evaluates the use of tirzepatide in overweight/obese adults with type 1 diabetes

Researchers create new platform to identify proteins for targeted treatment of disease

Study shows cellular, molecular overlaps in ALS and FTLD

Scientists uncover four proteins that govern the identity of anaplastic large cell lymphoma

Weill Cornell Medicine receives $1.65 million grant for groundbreaking RNA research

Study highlights global fertility decline and its implications for the future

Scientists shed light on key immune regulators involved in Alzheimer’s and other disorders of lipid-rich tissues

Investigational gene therapy shows promise for rare childhood neurodegenerative disease

Enhancing the safety and efficacy of breast and ovarian cancer treatment

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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