B-cell maturation protein (BCMA) from ACROBiosystems

BCMA Molecule Information

Name:B-cell maturation protein
Target Synonym:Tumor necrosis factor receptor superfamily member 17?B-cell maturation protein?CD_antigen: CD269?BCMA?TNFRSF17?BCM
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:18
Lastest Research Phase:Phase ?

BCMA Molecule Synonym Name


BCMA Molecule Background

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

BCMA References

BCMA Related Molecule