Cell Guidance Systems' PODS Proteins

If you are considering custom protein production, explore the benefits of PODS proteins only available from Cell Guidance Systems.

Custom PODS™ Protein Production Service.

Polyhedrin Delivery System (PODS™) provides a highly effective solution to the inherent instability of proteins. PODS™ technology exploits the natural properties of the polyhedrin protein which forms crystals when expressed in a cell. PODS™ crystals are formed when a tagged protein of interest (cargo protein) is co-expressed with the Bombyx mori cypovirus polyhedrin protein.

The polyhedrin protein forms regular, cubic crystals within which a cargo protein specifically binds via a short protein tag. PODS™ technology provides a slow-release depot formulation for the cargo protein.

A range of  PODS™ proteins are available as catalog products. However, if you wish to have a specific protein made, please contact us for a quote and terms and conditions. In general, we provide a 12 month period of exclusivity for a custom protein before adding it to our catalog.

Typically PODS™ proteins can be prepared in 3-4 months and 5 billion PODS™ crystals are delivered to the customer.